Protein

MIA_00482_1

Length
707 amino acids

Browser: contig01:1378538-1380662+

Protein function

EGGNOG:0PHYZHSP90Heat shock protein
SGD closest match:S000006161HSP82ATP-dependent molecular chaperone HSP82
CGD closest match:CAL0000201062HSP90Heat shock protein 90 homolog

Protein alignments

%idAln lengthE-value
A0A060T0B2_BLAAD85.651%6760.0ARAD1C15158p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C15158g PE=3 SV=1
UniRef50_C6HA5276.071%6770.0ATP-dependent molecular chaperone HSC82 n=1 Tax=Ajellomyces capsulatus (strain H143) TaxID=544712 RepID=C6HA52_AJECH
MCA_03013_192.195%4100.0MCA_03013_1
A0A0J9X2F1_GEOCN90.488%4100.0Similar to Saccharomyces cerevisiae YMR186W HSC82 Cytoplasmic chaperone of the Hsp90 family OS=Geotrichum candidum GN=BN980_GECA01s00703g PE=3 SV=1
A0A1E3PMV5_9ASCO86.829%4100.0HSP90-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_40919 PE=3 SV=1
Q6CCN4_YARLI88.537%4100.0YALI0C07953p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C07953g PE=3 SV=1
HSP90_CANAL84.390%4100.0Heat shock protein 90 homolog OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=HSP90 PE=3 SV=1
A0A1E4TM65_9ASCO84.634%4100.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_43430 PE=3 SV=1
A0A167CHU9_9ASCO87.561%4100.0Hsp90 family chaperone HSP82 OS=Sugiyamaella lignohabitans GN=HSP82 PE=3 SV=1
HSP82_YEAST86.829%4100.0ATP-dependent molecular chaperone HSP82 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HSP82 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0394

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 707

Detailed signature matches

  1. Family IPR001404
    Heat shock protein Hsp90 family
    1. PIRSF002583 (HSP90_...)
    2. MF_00505 (HSP90)
    3. PF00183 (HSP90)
  2. Domain IPR003594
    Histidine kinase-like ATPase, C-terminal domain
    1. G3DSA:3.30.56...
    2. PF02518 (HATPase_c)
    3. SSF55874 (ATPase do...)
    4. SM00387 (HKATPase_4)
  3. Domain IPR020575
    Heat shock protein Hsp90, N-terminal
    1. PR00775 (HEATSHOCK90)
  4. Domain IPR020568
    Ribosomal protein S5 domain 2-type fold
    1. SSF54211 (Ribosomal...)
  5. SITE IPR019805
    Heat shock protein Hsp90, conserved site
    1. PS00298 (HSP90)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. SSF110942 (HSP90 C-...)
  3. cd00075 (HATPase_c)
  4. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. Mg2+ binding site ...
  3. G-X-G motif cd00075

Protein sequence

>MIA_00482_1
MSAPVKSESYEFQAEISQLMSLIINTVYSNKEIFLRELISNASDAIDKIRYEALSDPSKLETEPELFIRITPKKEQKVLE
IRDSGIGMTKADLVNNLGTIAKSGTKAFMEALSAGADVSMIGQFGVGFYSLFLVADRVQVISKNNDDEQYIWESSAGGKF
TITLDEENERISRGTVIRLFLKDDQLEYLEEKRIKDVVKRHSEFVSYPIQLVVTKEIEKEVPVEESEEKTEEESDEKKPK
IEEVDDEEDKKDEKKVKKIKETVTENEELNKTKPLWTRNPADITKEEYAAFYKSISNDWEDHLAVKHFSVEGQLEFRAIL
FIPSRAPFDLFETRKKKNNIKLYVRRVFITDDAEELIPEWLSFVKGVVDSEDLPLTLSREMLQQNKILKVIKKNIVKKLI
ETFNEIAEDRELFEKFYSAFGKNIKLGVHEDSTNRAALAKLLRYNSTKSPEELTSFQDYITRMPAHQKNIYYITGESIKA
VEKSPFLDALKAKDFEVLYMVDPIDEYAMAQLKEFEDKKLVNITKDFELEETEEEKKQREEEIKEFEPLTKALKEILGDQ
VEKVVVSHKLIDAPAAIRTGQFGWSANMERIMKAQALRDSSMSAYMASKKTFEISPKSPIIKELKHKVEEDGTQDRTVRD
LTTLLYETALLTSGFTLDEPNSFASRINRLISLGLNIDESEETTAAAPVAEAVPAESAAESAMEEVD

GO term prediction

Biological Process

GO:0006457 protein folding
GO:0006950 response to stress

Molecular Function

GO:0005524 ATP binding
GO:0051082 unfolded protein binding

Cellular Component

None predicted.