Protein

MIA_00458_1

Length
307 amino acids

Browser: contig01:1305584-1306508-

Protein function

EGGNOG:0PGX7HMX1Heme oxygenase
SGD closest match:S000004195HMX1Heme-binding protein HMX1
CGD closest match:CAL0000188588HMX1Hmx1p

Protein alignments

%idAln lengthE-value
MCA_01341_163.924%3164.84e-140MCA_01341_1
A0A0J9X6I1_GEOCN60.595%2691.09e-117Similar to Saccharomyces cerevisiae YLR205C HMX1 ER localized heme oxygenase OS=Geotrichum candidum GN=BN980_GECA04s03607g PE=4 SV=1
Q6C7U4_YARLI56.296%2707.81e-110YALI0D25278p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D25278g PE=4 SV=1
UniRef50_Q6C7U456.296%2701.81e-106YALI0D25278p n=8 Tax=Saccharomycetales TaxID=4892 RepID=Q6C7U4_YARLI
A0A1E3PDM5_9ASCO57.196%2718.18e-106ER localized, heme-binding peroxidase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53190 PE=4 SV=1
A0A1E4TJ39_9ASCO45.560%2592.67e-76Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_23332 PE=4 SV=1
Q5AB97_CANAL45.660%2651.75e-74Hmx1p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=HMX1 PE=4 SV=1
HMX1_YEAST40.441%2721.68e-62Heme-binding protein HMX1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HMX1 PE=2 SV=3

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0055

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 307

Detailed signature matches

  1. Family IPR016053
    Haem oxygenase-like
    1. PF01126 (Heme_oxyge...)
  2. Family IPR002051
    Haem oxygenase
    1. PIRSF000343 (HMX1)
  3. Domain IPR016084
    Haem oxygenase-like, multi-helical
    1. SSF48613 (Heme oxyg...)
    2. G3DSA:1.20.91...
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. TMhelix
  4. TRANSMEMBRANE (Tran...)

Protein sequence

>MIA_00458_1
MAFDPHAGSYDTKKKFSQEEVIPAPNDVGALANRINKATHAIHNKINNLISLKMVFALRDPKIYRQGIIAFYYVFREFER
IWLEYLEQDPTTLTEDQREIYDILQQVWTPALARTEPLELDLSFYYHTESPKAFAQKYQNPIMSEQVSMLDHMNKVLHEK
PYLILAYAHTLYLALFAGGRIMRSSVAKSTGLFPIVPGKTQEEVSDNGTHLFKFPMADDEDALRLDFKRRFELATRNSLT
EEQKLEIIAESEEIFRRNIAAVDEVSRKNQRAIVQKFGYKATKAFSIILIIVSIFLLFLQMRKFFNF

GO term prediction

Biological Process

GO:0006788 heme oxidation
GO:0055114 oxidation-reduction process

Molecular Function

GO:0004392 heme oxygenase (decyclizing) activity

Cellular Component

None predicted.