Protein

MIA_00251_1

Length
968 amino acids

Browser: contig01:707073-709980+

Protein function

EGGNOG:0PH3VFG05973.1Glucosidase II alpha subunit
SGD closest match:S000000433ROT2Glucosidase 2 subunit alpha
CGD closest match:CAL0000191464ROT2Glucan 1\3-alpha-glucosidase ROT2

Protein alignments

%idAln lengthE-value
MCA_04640_165.584%9850.0MCA_04640_1
A0A0J9X846_GEOCN61.889%9210.0Similar to Saccharomyces cerevisiae YBR229C ROT2 Glucosidase II catalytic subunit required for normal cell wall synthesis OS=Geotrichum candidum GN=BN980_GECA05s01242g PE=3 SV=1
UniRef50_A0A0J9X84661.889%9210.0Similar to Saccharomyces cerevisiae YBR229C ROT2 Glucosidase II catalytic subunit required for normal cell wall synthesis n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9X846_GEOCN
A0A167FIM1_9ASCO56.103%9750.0Glucan 1,3-alpha-glucosidase ROT2 OS=Sugiyamaella lignohabitans GN=ROT2 PE=3 SV=1
A0A060TA68_BLAAD52.549%9610.0ARAD1C42966p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C42966g PE=3 SV=1
A0A1E3PJD4_9ASCO50.052%9690.0Alpha glucosidase II, alpha subunit OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_51907 PE=3 SV=1
Q6CFI8_YARLI48.788%9490.0YALI0B06600p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B06600g PE=3 SV=1
A0A1E4THI2_9ASCO45.963%9660.0Glycoside hydrolase family 31 protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_121614 PE=3 SV=1
Q5A4X3_CANAL48.000%9000.0Glucan 1\3-alpha-glucosidase ROT2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ROT2 PE=3 SV=1
GLU2A_YEAST40.644%9940.0Glucosidase 2 subunit alpha OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ROT2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3167
Predicted cleavage: 14

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 900 968

Detailed signature matches

  1. Family IPR000322
    Glycoside hydrolase family 31
    1. PF01055 (Glyco_hydr...)
  2. Domain IPR011013
    Galactose mutarotase-like domain
    1. SSF74650 (Galactose...)
  3. Domain IPR025887
    Glycoside hydrolase family 31, N-terminal domain
    1. PF13802 (Gal_mutaro...)
  4. Domain IPR017853
    Glycoside hydrolase superfamily
    1. SSF51445 ((Trans)gl...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:2.60.40...
  2. G3DSA:2.60.40...
  3. G3DSA:3.20.20.80
  4. NON_CYTOPLASM... (N...)
  5. SIGNAL_PEPTIDE (Sig...)
  6. SIGNAL_PEPTID... (S...)
  7. SIGNAL_PEPTID... (S...)
  8. SIGNAL_PEPTID... (S...)
  9. SSF51011 (Glycosyl ...)
  10. SignalP-noTM
  11. TMhelix
  12. cd06603 (GH31_GANC_...)
  13. cd14752 (GH31_N)

Residue annotation

  1. active site cd14752
  2. putative active si...
  3. catalytic site cd0...

Protein sequence

>MIA_00251_1
MKSRTFPTAFALLGIYLLICIALFSSPSQAVKHNLFRTCEQNKFCKRNRHIADYASSQTLEGKEWSSPYEIDVASVALSK
DKTAKLTGNILKTTPKGFVTLPFNLSFLKSGIVRFTLDELKRQDGNIEISGSKKLRKERYNDLDKWTLIEENLVLSDGTE
ISIEQVDHDLKISYGGGNKLFIQSNPFSIKFYRNEELQVVLNERGLLNLEHWRAQPPKPNEGEEQVKDEELNAWELEEGM
WEDTFDGKTDKKVRGPESIALDVSFVGFKHVYGIPEHADSLSLRETRGQAEGHHKDPYRLFNVDIFEYEVDSPMAMYGSI
PFMQAHKPGSSVGLYWNNAADTYVDIIKTRPSNDKMISSLQSTQTHWISESGLIDVFVILADDPSEVNDLYGSLTGYALL
PQSFAIGHHQCRWNYNDKADVLEVNSNFDKYGIPYDVIWLDIEYTDDKKYFTWNEKAFKGHDEMIKELDETKRKLVAIID
PHIKAVKGYKPFETLESKNLAICNTEDKPYHGHCWPGESVWIDTLSPEARKLWISWFGKDQSWAGDNDNLHIWNDMNEPS
VFSGPETTMDKNTVHSGGWEHRDVHNLYGMTYHNATLDALNERYKYKQRPFVLTRAYFAGSQRTAAMWTGDNMAKWEYLK
AATPMILTSGVAGMPFAGADVGGFFGNPSTELLTRWYQAGAFYPFFRAHAHIDSKRREPWLAGEPYTNIIKSAIQLRYKL
LPTFYSAFYQASIDGSPILKPLYYVTPNNEDSFAIDDEFFVGDSGILVKPVTEEGATSVNLYIPDDEFYYGYDDHEKIYK
GVGHYSIEAPLNTIPMLLRGGHIHARRDRLRRSATLMKYDPYTLVISLDKNGQAKGEMFIDDGESYNYEKGEYLRPEFEF
DVATGILSGTNEDETVLTPYLKSLWVEKIIIIGANASQIKEGTAEVVEQDEAGAELKRTVQVKRLSKNSAVVVGPRVKLA
KDWSIEFK

GO term prediction

Biological Process

GO:0005975 carbohydrate metabolic process

Molecular Function

GO:0003824 catalytic activity
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0030246 carbohydrate binding

Cellular Component

None predicted.