Protein

MIA_00202_1

Length
511 amino acids

Browser: contig01:572986-574522+

Protein function

EGGNOG:0PF8VRRP3Required for pre-ribosomal RNA processing. Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA (By similarity)
SGD closest match:S000001107RRP3ATP-dependent rRNA helicase RRP3
CGD closest match:CAL0000176052RRP3ATP-dependent rRNA helicase RRP3

Protein alignments

%idAln lengthE-value
MCA_00729_176.627%4150.0MCA_00729_1
A0A0J9X7X9_GEOCN72.513%3820.0Similar to Saccharomyces cerevisiae YHR065C RRP3 Protein involved in rRNA processing OS=Geotrichum candidum GN=BN980_GECA05s03750g PE=3 SV=1
A0A1E3PMW2_9ASCO69.029%3810.0ATP-dependent rRNA helicase rrp3 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_24372 PE=3 SV=1
RRP3_YARLI63.789%4170.0ATP-dependent rRNA helicase RRP3 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=RRP3 PE=3 SV=1
UniRef50_Q9P6N862.857%4200.0ATP-dependent rRNA helicase rrp3 n=281 Tax=Eukaryota TaxID=2759 RepID=RRP3_SCHPO
A0A1E4TAE2_9ASCO66.406%3840.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3320 PE=3 SV=1
RRP3_CANAL64.000%3751.89e-173ATP-dependent rRNA helicase RRP3 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RRP3 PE=3 SV=3
A0A167FSU8_9ASCO59.635%3845.12e-173RNA-dependent ATPase RRP3 OS=Sugiyamaella lignohabitans GN=RRP3 PE=3 SV=1
RRP3_YEAST61.680%3811.07e-170ATP-dependent rRNA helicase RRP3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RRP3 PE=1 SV=2
A0A060TBX2_BLAAD56.325%4191.68e-159ARAD1D31240p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D31240g PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.5931
Predicted cleavage: 19

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 50 100 150 200 250 300 350 400 450 511

Detailed signature matches

  1. Domain IPR014014
    RNA helicase, DEAD-box type, Q motif
    1. PS51195 (Q_MOTIF)
  2. Domain IPR014001
    Helicase superfamily 1/2, ATP-binding domain
    1. PS51192 (HELICASE_A...)
    2. SM00487 (ultradead3)
  3. Domain IPR011545
    DEAD/DEAH box helicase domain
    1. PF00270 (DEAD)
  4. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  5. Domain IPR001650
    Helicase, C-terminal
    1. PS51194 (HELICASE_CTER)
    2. SM00490 (helicmild6)
    3. PF00271 (Helicase_C)
  6. SITE IPR000629
    ATP-dependent RNA helicase DEAD-box, conserved site
    1. PS00039 (DEAD_ATP_H...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.40.50...
  3. cd00079 (HELICc)
  4. cd00268 (DEADc)
  5. mobidb-lite (disord...)

Residue annotation

  1. ATP binding site c...
  2. Mg++ binding site ...
  3. motif III cd00268
  4. nucleotide binding...
  5. ATP-binding site c...

Protein sequence

>MIA_00202_1
MSKFAVPARKFKASEAKVKKSAGSKTKGSDTASEAKKLAAKIKALDAQKKATEDKSSTSASATENDTPKLKVASSTTNAE
GLEEVAELAEGEEPQTFAELGVIPPLCEACDALKFSKPTPIQAQAIPWALQGRDIIGLAQTGSGKTAAFALPILQALWHA
PAPLFCCVLAPTRELAVQIAEQFEALGAGIGLRCAVIVGGMDMLQQSMMLARKPHVIVATPGRLVDHLENTKGFSLKSLK
YLVMDEADRLLEAEFQTVMGRLLTALPKTGRHTYLFSATMTSQVDRLRRASLHNPVKVAVSSKYDTASSLLQYYMFIPMV
HKDTYLVYLLQQMEGHTAIVFARTISDAERLALALRELGFRAVPLHGRMNQAARLGALNKFKAGARNILVATDVAARGLD
IPSVDIVINYDIPDDSKAYIHRVGRTARAGRSGKSVTFVTQYNLDVYQRLEATLGKKLDEYKVDKSEVMALSTRVGEALR
EALLKLRELEAKRSRSGGKNRTRDDGNFEEA

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003676 nucleic acid binding
GO:0005524 ATP binding

Cellular Component

None predicted.