Protein

MIA_00186_1

Length
1,735 amino acids

Browser: contig01:533221-538501+

Protein function

EGGNOG:0PFE1FG01497.1Ras GTPase activating protein
SGD closest match:S000006163IQG1Ras GTPase-activating-like protein IQG1
CGD closest match:CAL0000175167IQG1Ras GTPase-activating-like protein IQG1

Protein alignments

%idAln lengthE-value
A0A0J9X436_GEOCN55.535%15990.0Similar to Saccharomyces cerevisiae YPL242C IQG1 Essential protein required for determination of budding pattern OS=Geotrichum candidum GN=BN980_GECA02s03497g PE=4 SV=1
UniRef50_A0A0J9X43655.535%15990.0Similar to Saccharomyces cerevisiae YPL242C IQG1 Essential protein required for determination of budding pattern n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X436_GEOCN
MCA_03401_163.299%13460.0MCA_03401_1
A0A167FYX6_9ASCO50.139%14440.0Iqg1p OS=Sugiyamaella lignohabitans GN=IQG1 PE=4 SV=1
A0A1E3PEP2_9ASCO44.938%16000.0Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_28700 PE=4 SV=1
A0A060T5P0_BLAAD49.839%12460.0ARAD1B13376p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B13376g PE=4 SV=1
Q6CFR5_YARLI45.075%11980.0YALI0B04488p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B04488g PE=4 SV=2
A0A1E4TIY5_9ASCO38.048%11170.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_21430 PE=4 SV=1
IQG1_CANAL28.616%12795.33e-147Ras GTPase-activating-like protein IQG1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=IQG1 PE=1 SV=2
IQG1_YEAST23.529%11056.92e-53Ras GTPase-activating-like protein IQG1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=IQG1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.6794
Predicted cleavage: 35

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 200 400 600 800 1000 1200 1400 1600 1735

Detailed signature matches

  1. Domain IPR001715
    Calponin homology domain
    1. cd00014 (CH)
    2. PF00307 (CH)
    3. G3DSA:1.10.41...
    4. SSF47576 (Calponin-...)
    5. PS50021 (CH)
    6. SM00033 (ch_5)
  2. Domain IPR008936
    Rho GTPase activation protein
    1. SSF48350 (GTPase ac...)
  3. Domain IPR001936
    Ras GTPase-activating protein
    1. PS50018 (RAS_GTPASE...)
    2. PF00616 (RasGAP)
    3. SM00323 (RasGAP_2)
  4. Domain IPR000593
    RasGAP protein, C-terminal
    1. PF03836 (RasGAP_C)
  5. SITE IPR000048
    IQ motif, EF-hand binding site
    1. PS50096 (IQ)
    2. PF00612 (IQ)
    3. SM00015 (iq_5)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.10.50...
  3. G3DSA:1.20.5.190
  4. G3DSA:4.10.27...
  5. SSF143885 (RGC doma...)
  6. mobidb-lite (disord...)

Residue annotation

  1. putative actin bin...

Protein sequence

>MIA_00186_1
MDPNHSPYRAPLVASRNSAYVPKSPTRKPVHTRSSSLEKENFYDASPTSPTRKPVARQLPQVPPPPPPQQNDNNSLETPS
YSSYQYDYDDSANFSFSSQVTPTSSPRKGGAGMFSSSFSNTSPSRLSPSRLSLSRSVAQLVEGEDLSLFRKSATPHLRNL
AYSASKDSLLHLPGVTEDQEDVTGMMGRLRLQKTEDPVSHVASRNWMDNQRKYIQAYEYLCHIGEAKEWIEACLDDEIPS
IIKLEEALRDGVILARLTRQFAPHLVRRIFENPKLQYRHTDNINCFFNFLDEIGMPDLFTFELTDLYDKKNIPKVIYCVH
ALGYLLSNEGLAPPIGNLVGKLEFTEEEIKDTSRGLLASGLKLPNFSSVGAHFEPEPEPEPEPEPEPEMSEEEQILYELT
QCESNIIELQAISRGSQLRLSFYTDKYILSHSVSQLTRLQAIIRGIETRKKFQTRARTIGKAGDSLIPLQAIVRGNQLRS
DFTMFHQTLSGQGPAIVKLQSVIRGARIRHVKTIAAADLKKNTGVPMINLQSAIRGKLLRRNVSQFRREIFSIPALEPTI
ELQAIARGKLARYSRTERQMELRWCAQNMALFQAMIRGKLLRSHLSHKLNKIRNSEPWVHAFQAHIRGAMLRRRFQTHFS
EASSHQTTQLATVLQSVARAYLVRKAIEARKLSLIRFRGEVIVHQSNIRGALLRRNMVSFSCDLEKQKLSVAQLQGAARG
MLLRKSLNKFMNKLDTFVPIFTSFQAAIRARGVHLQHCDLSLQIHDTAPISVELQTLIRGNAFRAKFNGIKNILKKETPQ
IIAIQSMFRGGLLRQDFGDFICTLDLHSPAIVRLQSKFRGIMTRFNHALLLDEFDEAEDSIVAMQALWRGVNVRKAHAER
IKHFQQNLDKIIKIQSFVRAKKQGDSYKSLLSSANPPLATVKNFVHLLNDSDLDFEQEVQLEQSRKQVMDEIKHNEQLEQ
FITQLDVKIALLLKNKITIDEVVRHRNRGYSAAVSVTTPADMFDLKALNKSSRKRLELYQGLFYILQTQPVYLARVFRKQ
QSIVVSEKEAKELESMTVAMFGGVSSPKPREEYFLLKLIARSINDEVTEAHTIKSVQRGNFMWWKLLAALNRGPRERKTL
RQLLYASVTGVVSRADDELDLESDPLVIYRKSISEEEIRTGQLSQRNPNISVNEAIHDPDTRAAYISNMQKLRELTGDFL
NTVAENVDMIPYHIRYAASQLYNACKSAFPEEAKVEDRLLSLVGHVIFNLYLNPAIVAADNYGIINAALTPNQTRNLTEI
TKMLVQVSLLKPFSKEDVYLQPLNDFVKESAIKMRIIFKKVIAVEELAQHFQYSVYDDLTAHGRPTLYLKSSDIFAIHSM
VCRELDDMAPETDDPLRVVISELGALPNDASEILNIAKFTEIKLELNPSYCRIADPDADVNALLVATKRCLIYVLRVQSG
KNLVDILVSPVEDFHEEKYRNLLKEETEARERKRQKKEKNPYLPQEEDEEPLPDVYSNETGLGDLAALSYRELKRLTLER
ILELESYGKVERSDNYQALLNSIAVDIKSKRDRRAVRVREMEDARHTLEALSDKEKYLQKKLEAYNDYIEQAMLTLQTKK
GSKKRAVLPFSKQYFHMRDLQKSGRVPKFGSYKYSAATMLDRGILVELRGYSEKQYDKLTLTWSSDDVGVFKVEAAFGAV
ALPGAVAELTLDELLSQQYNNRQYLTLFDNMMTLNTNLTLHFIFKKFYGEGQSIF

GO term prediction

Biological Process

GO:0007165 signal transduction
GO:0043087 regulation of GTPase activity

Molecular Function

GO:0005515 protein binding

Cellular Component

None predicted.