Protein

MIA_00152_1

Length
499 amino acids

Browser: contig01:419461-420961+

Protein function

EGGNOG:0PFJXSNX4Sorting nexin, involved in the separation or division of vacuoles throughout the entire life cycle of the cells. Involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Golgi network, for cytoplasm to vacuole transport (Cvt), mitophagy, and pexophagy (By similarity)
SGD closest match:S000003573SNX4Sorting nexin-4
CGD closest match:CAL0000187768SNX4Sorting nexin-4

Protein alignments

%idAln lengthE-value
MCA_06059_172.519%3930.0MCA_06059_1
A0A0J9XK98_GEOCN60.358%3913.33e-167Similar to Saccharomyces cerevisiae YJL036W SNX4 Sorting nexin OS=Geotrichum candidum GN=BN980_GECA25s01099g PE=4 SV=1
A0A060T810_BLAAD48.667%4504.71e-155ARAD1D06886p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D06886g PE=4 SV=1
A0A167D465_9ASCO52.311%4111.29e-149Snx4p OS=Sugiyamaella lignohabitans GN=SNX4 PE=4 SV=1
UniRef50_A0A167D46552.311%4113.55e-146Snx4p n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A167D465_9ASCO
A0A1E3PKH8_9ASCO48.905%4114.34e-136Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_24834 PE=4 SV=1
Q6C5Z2_YARLI44.330%3884.16e-115YALI0E13904p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E13904g PE=4 SV=2
SNX4_YEAST36.041%3941.57e-84Sorting nexin-4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SNX4 PE=1 SV=1
SNX4_CANAL31.494%3081.59e-39Sorting nexin-4 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SNX4 PE=3 SV=2
A0A1E4TCW5_9ASCO26.812%2761.69e-15Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_11595 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0806

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 450 499

Detailed signature matches

  1. Domain IPR001683
    Phox homologous domain
    1. PF00787 (PX)
    2. PS50195 (PX)
    3. SM00312 (PX_2)
    4. G3DSA:3.30.15...
    5. SSF64268 (PX domain)
  2. Domain IPR015404
    Sorting nexin Vps5-like, C-terminal
    1. PF09325 (Vps5)
  3. Domain IPR027267
    Arfaptin homology (AH) domain/BAR domain
    1. SSF103657 (BAR/IMD ...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.20.12...
  3. cd06863 (PX_Atg24p)
  4. mobidb-lite (disord...)

Residue annotation

  1. phosphoinositide b...

Protein sequence

>MIA_00152_1
MSSNIPDNTSEDSSEPWTDNRPDAEISLEDESPSSYNPQEPSDNATAAPTSTPHAVLSSTATTPDLASANNPDEDGEDEI
PKYNISLNDNLPAQPDSSAPTESSAQTSTFIHSTVTDPQKEQDGSQNAYISYLITTETNVPTFQSHLVKVRRRFSDFYFL
YSFLVSEYPACAVPPLPDKNRLEYIKGDRFGPEFTLKRAASLNRFLDRISMHPILRKASTYLIFLESNEWHAYKRSLAIR
QQTSPEVPSVLDGLSDSLLNAFSKVHTPNEELIDVKAKMDKLDENLLQVERAFLRVLRRKGDISSDFDDFSQQLIRLAGL
EKNLEPEIVSFANGTEFISRATLKLRDQIDNGYIISLRDLQNYVTSIKSLIKLREQKQLDYEALIDYLSKAQQEKQAMQT
GTGSKNFFRARMEDMRGIDHQNAKNERLRKLDTKIQSLSQEVDNVKAASDTFQELAINEIAIFENTKTQEMKETLSTLAD
DHINYYQSLIHEWSALLKT

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0035091 phosphatidylinositol binding

Cellular Component

None predicted.