Protein

MIA_00064_1

Length
952 amino acids

Browser: contig01:164910-167769-

Protein function

EGGNOG:0PI8ETPS2K16055 trehalose 6-phosphate synthase phosphatase EC 2.4.1.15 3.1.3.12
SGD closest match:S000002481TPS2Trehalose-phosphatase
CGD closest match:CAL0000193855TPS2Trehalose-phosphatase

Protein alignments

%idAln lengthE-value
MCA_03956_174.941%8500.0MCA_03956_1
A0A0J9XKA7_GEOCN63.039%9280.0Similar to Saccharomyces cerevisiae YDR074W TPS2 Phosphatase subunit of the trehalose-6-phosphate synthase/phosphatase complex OS=Geotrichum candidum GN=BN980_GECA22s00637g PE=4 SV=1
A0A1E3PQD6_9ASCO56.699%8360.0Phosphatase subunit of the trehalose-6-phosphate synthase/phosphatase complex OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_21412 PE=4 SV=1
UniRef50_A0A1D2VB7554.715%8590.0Glycosyltransferase family 20 protein n=18 Tax=Ascomycota TaxID=4890 RepID=A0A1D2VB75_9ASCO
A0A060T655_BLAAD56.357%8180.0ARAD1B16654p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B16654g PE=4 SV=1
A0A167CI15_9ASCO52.738%8400.0Trehalose-phosphatase TPS2 OS=Sugiyamaella lignohabitans GN=TPS2 PE=4 SV=1
Q5AI14_CANAL51.529%8500.0Trehalose-phosphatase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TPS2 PE=1 SV=1
Q6C939_YARLI52.078%8180.0YALI0D14476p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D14476g PE=4 SV=1
TPS2_YEAST45.642%8720.0Trehalose-phosphatase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TPS2 PE=1 SV=3
A0A1E4TGL0_9ASCO44.790%8350.0Glycosyltransferase family 20 protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_17121 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1422
Predicted cleavage: 12

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 800 900 952

Detailed signature matches

  1. Family IPR006379
    HAD-superfamily hydrolase, subfamily IIB
    1. TIGR01484
  2. Family IPR003337
    Trehalose-phosphatase
    1. PF02358 (Trehalose_...)
    2. TIGR00685
  3. Domain IPR001830
    Glycosyl transferase, family 20
    1. PF00982 (Glyco_tran...)
    2. cd03788 (GT1_TPS)
  4. Domain IPR023214
    HAD-like domain
    1. SSF56784 (HAD-like)
    2. G3DSA:3.40.50...
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.30.70...
  2. G3DSA:3.40.50...
  3. SSF53756 (UDP-Glyco...)
  4. cd01627 (HAD_TPP)
  5. mobidb-lite (disord...)

Residue annotation

  1. active site cd03788
  2. homotetramer inter...
  3. HAD signature moti...
  4. active site cd01627
  5. active site pocket...
  6. HAD signature moti...
  7. HAD signature moti...
  8. HAD signature moti...

Protein sequence

>MIA_00064_1
MTPALGALGREAASFPDTVSDKAAISLMPPVDSSAPRSMQEAQERRLSLDADPLDADTPSSTTPPPSTAPSSSSSGTTAN
PYPLIYNPKDSPPNLHVSGRVINALSQMPHAVVYNADDKSFDLRHRRGNSALYSALSFLKNHEHWESLIVAWTGEIEAKA
TVAIDNVHQDNVDVSPDDAKHIEQMYRDREKDYGETHPIWLLGPDQFRWREYAEKIIWPILHYIQGEPTDGIQEQHWWRS
YLTFNEAYANRIIDIYQPGDIIWIHDYYLLLLPQLLRMKLPNAYIGSFLHSPFSSSEYFRVIPKRKELLEGMLGANLVAT
QSYAFSRHFISACTRLLNLESRPNYISAYGVHVSVDTIPIGIDAETVERDAFSPIVDKKVSALRSLYPNMKLIIGRDRLD
SVRGVVQKLHAYEMFLNLYPEWIGKVVLIQVTSPAYANTDKMEEKIAEMISHINGTYGSLDYSPIQHYPRHVARDEYFAL
LRGADLGLITSVRDGMNTTSLEFVICQKFKNSPLILSEFTGTAGLLVDALQVNPWDSVGVAQTINQCLLQSPERNAVVQN
HLYKTVTTNTVHDWVVRFLSRLIHNLSRHDQSHMTPTLDRALLLQQYQKAQKRLFLFDYDGTLTPIVREPSAAIPSARLY
KTLELLTADPRNHVWIISGRDSEFLDKWLGHNKALGFSAEHGCFFKNEGSSTWVNLAEQVDMSWRTDARAIFDYFTERTQ
GSHVEVKQAALTWHYRRADPELGQFQAQALKAQLEKQLVGKYDVEVMEGKANIEVRPRQFNKGEIVKRLVREIGKGFDGG
RPDFVYCLGDDKTDEDMFTVVSGLSAPSVESSSSGDHDTEEVSESNAKAAKAAYERGLDGLFPVTVGPANKRTGAAWHLI
DPEAVLDTLAVLTGEIPLEEVVGLVDIDERGRSVSSAGLTALTTPGAKFTLDPKTTQPPDDPEVDGLEPDGP

GO term prediction

Biological Process

GO:0005992 trehalose biosynthetic process

Molecular Function

GO:0003824 catalytic activity

Cellular Component

None predicted.