Protein

MIA_00036_1

Length
745 amino acids

Browser: contig01:84209-86447-

Protein function

EGGNOG:0PGDJFG05522.1DNA repair and recombination protein pif1
SGD closest match:S000001073RRM3ATP-dependent DNA helicase RRM3
CGD closest match:CAL0000185430PIF1ATP-dependent DNA helicase PIF1

Protein alignments

%idAln lengthE-value
MCA_00495_144.227%5636.14e-140MCA_00495_1
A0A0J9X617_GEOCN43.421%5321.17e-131ATP-dependent DNA helicase PIF1 OS=Geotrichum candidum GN=PIF1 PE=3 SV=1
UniRef50_A0A0J9X61743.421%5322.40e-128ATP-dependent DNA helicase PIF1 n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X617_GEOCN
PIF1_CANAL40.183%5454.46e-113ATP-dependent DNA helicase PIF1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PIF1 PE=3 SV=2
A0A060THB6_BLAAD36.716%5429.17e-114ATP-dependent DNA helicase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D29260g PE=3 SV=1
A0A167DT29_9ASCO40.260%5391.92e-112ATP-dependent DNA helicase OS=Sugiyamaella lignohabitans GN=RRM3 PE=3 SV=1
RRM3_YEAST37.798%5456.42e-112ATP-dependent DNA helicase RRM3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RRM3 PE=1 SV=1
Q6CAI0_YARLI31.463%5882.85e-77ATP-dependent DNA helicase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D02607g PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2470

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 745

Detailed signature matches

  1. Family IPR010285
    DNA helicase Pif1-like
    1. PF05970 (PIF1)
  2. Family IPR003840
    DNA helicase
    1. PF02689 (Herpes_Hel...)
  3. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  4. Domain IPR003593
    AAA+ ATPase domain
    1. SM00382 (AAA_5)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.50...
  2. cd00009 (AAA)
  3. mobidb-lite (disord...)

Residue annotation

  1. Walker A motif cd0...
  2. ATP binding site c...
  3. Walker B motif cd0...

Protein sequence

>MIA_00036_1
MVTTLGEKTGESKKDILEKAKDKPNSTLHLGAFEEMSSSSRAYKNEPLDDSSDDDLIEISVSKTPHPNKTIKKDFKAPEN
RQHTSPSAFHSHSSPIKKRRSSLESSTWIDKNNDFKHSQHEHSPSRTSPDKSFLLSKEQQLVIRLALKGRSLFYTGAAGT
GKSLLLRCLIDRLRKRHNTVAVTSSTGIAAVNVGGITLHSFAGVGLAKEDAKTLVKKVRKNESACDRWRETSVLVIDEVS
MVDGLFFTKLEYIARCIRCNNFPFGGIQVICTGDFFQLPPVPDKYIPDDGHSFVSTPRVYCFETEAWHKTITQCIVLQQV
FRQKGDNEFIEILNAMRLGRLTDKMNEKLRSLDRPVVYKDGITPTMLYATRNKVQQYNSTKLAELPGKRYFYTSTDIIPE
NVPSAKVTQALKRLDEIVSSEIELRQDCQIMIVRNIIDSGLANGTLGRVLGFLTQRGYTHVQGIASREQISTSSPEFQQL
VRDHQAKEEEKYNNGKTKIYISCHKVVDDDTPLPIISLTTDTMGSSRLVHQLNPIDNFVTIGGKPEHIESTSSNEFKIPL
FSKNGSEIEELKQPPEVKRIQIPLIYSWAMSIHKAQGQTLPRVRIDLANIFESGHAYVAISRATSTKTLEVLNYNPAKVT
VDPKVAAFYRNLEKAAIKLSPDEQEYSNQKQDAVPQLKNEQESPLTRKRKIFNPTKGNELHNESTKKQREEVKHEQDIKP
KHEYEPVSQNQVIDIDSDSSIEILD

GO term prediction

Biological Process

GO:0000723 telomere maintenance
GO:0006281 DNA repair

Molecular Function

GO:0003678 DNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding

Cellular Component

None predicted.