Protein

MCA_mt_19351052

Length
385 amino acids


Gene name: cob

Description: Cytochrome b

Browser: mtDNA:10862-14719+

RNA-seq: read pairs 149, FPKM 4.8, percentile rank 17.1% (100% = highest expression)

Protein function

Annotation:cobCytochrome b
KEGG:K00412CYTB ubiquinol-cytochrome c reductase cytochrome b subunit
EGGNOG:0PJSICOBComponent of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
SGD closest match:S000007270COBCytochrome b
CGD closest match:CAL0000196083COBCytochrome b

Protein alignments

%idAln lengthE-value
MIA_mt_1935094490.91%3850.0MIA_mt_19350944
A0A0A1I5E4_GEOCN89.61%3850.0Cytochrome b OS=Geotrichum candidum GN=cob PE=3 SV=1
CYB_CANAL66.23%3850.0Cytochrome b OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=COB PE=3 SV=1
A0A060RCS9_BLAAD66.23%3851e-180Cytochrome b OS=Blastobotrys adeninivorans GN=cob PE=3 SV=1
CYB_YARLI69.09%3851e-179Cytochrome b OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=COB PE=3 SV=1
CYB_YEAST64.42%3855e-175Cytochrome b OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=COB PE=1 SV=3
UniRef50_A0A166AUE957.22%3881e-142Cytochrome c oxidase subunit 2 n=2 Tax=Lecanora strobilina TaxID=1518595 RepID=A0A166AUE9_9LECA
A0A167BWA8_9ASCO70.90%1342e-42Cytochrome b OS=Sugiyamaella lignohabitans GN=COB PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1731

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 50 100 150 200 250 300 350 385

Detailed signature matches

    1. cd00284 (Cytochrome...)
    2. PF00033 (Cytochrome_B)
    3. PS51002 (CYTB_NTER)
    1. SSF81342 (Transmemb...)
    1. SSF81648 (a domain/...)
    2. PS51003 (CYTB_CTER)
    3. PF00032 (Cytochrom_B_C)
    4. cd00290 (cytochrome...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. TRANSMEMBRANE (Tran...)

Residue annotation

  1. Qi binding site cd...
  2. intrachain domain ...
  3. interchain domain ...
  4. heme bH binding si...
  5. heme bL binding si...
  6. Qo binding site cd...
  7. intrachain domain ...
  8. interchain domain ...
  9. Qi binding site cd...
  10. Qo binding site cd...

Protein sequence

>MCA_mt_19351052
MALRKKNEFLGLANSYLMDSPQPSTMSYWWNIGSLLGLCLVIQLGTGMFLAMHYSSNLELAFMSVEHMMRDVSSGWALRY
AHANGAAFFFMLMYAHMARGMYYGSYKSPRVAVWMMGVMMFLLLIITGFMGYVLPMGQMSLWGATVITNLMSAMPYMGQD
VVEFIWGGPSVGNPTLQRFFALHYLLPFVLAALTMMHFIAFHEHGSSNPLGMTGNMDRLPFSPYFMFKDLVTVFVFLFVY
SAFVFFNPNTLGHPDNYMPANPMVTPASIVPEFYLLPFYAMLRAIPSKLGGVMAMVAAILMLMILPMSDRSMVRGNAFKV
LSKLLYGLFLCNFLLLGALGSQHIEVPFMALGQFATMFYFSYFMMLLPAMTMLENMLFYIGQQSK

GO term prediction

Biological Process

GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c
GO:0022904 respiratory electron transport chain

Molecular Function

GO:0008121 ubiquinol-cytochrome-c reductase activity
GO:0009055 electron carrier activity
GO:0016491 oxidoreductase activity

Cellular Component

GO:0016020 membrane
GO:0045275 respiratory chain complex III