Protein
MCA_06508_1
Length
571 amino acids
Gene name: GAD1
Description: Glutamate decarboxylase Gad1
Browser: contigD:4444361-4446077-
RNA-seq: read pairs 13666, FPKM 295.2, percentile rank 91.7% (100% = highest expression)
Protein function
| Annotation: | GAD1 | Glutamate decarboxylase Gad1 | |
|---|---|---|---|
| KEGG: | K01580 | E4.1.1.15 | glutamate decarboxylase [EC:4.1.1.15] |
| EGGNOG: | 0PGV1 | glutamate decarboxylase | |
| SGD closest match: | S000004862 | GAD1 | Glutamate decarboxylase |
| CGD closest match: | CAL0000195622 | GAD1 | Glutamate decarboxylase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_02234_1 | 71.17% | 555 | 0.0 | MIA_02234_1 |
| A0A0J9XB41_GEOCN | 65.05% | 578 | 0.0 | Glutamate decarboxylase OS=Geotrichum candidum GN=BN980_GECA08s02727g PE=3 SV=1 |
| Q6C2F2_YARLI | 59.78% | 552 | 0.0 | Glutamate decarboxylase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F08415g PE=3 SV=1 |
| A0A1E3PL64_9ASCO | 59.54% | 571 | 0.0 | Glutamate decarboxylase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46515 PE=3 SV=1 |
| A0A060TG23_BLAAD | 58.70% | 552 | 0.0 | Glutamate decarboxylase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D19712g PE=3 SV=1 |
| A0A167CUR4_9ASCO | 53.31% | 574 | 0.0 | Glutamate decarboxylase OS=Sugiyamaella lignohabitans GN=GAD1 PE=3 SV=1 |
| A0A1E4TM36_9ASCO | 59.10% | 489 | 0.0 | Glutamate decarboxylase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_90990 PE=3 SV=1 |
| UniRef50_A0A0H1BN67 | 57.60% | 467 | 0.0 | Glutamate decarboxylase n=72 Tax=Fungi TaxID=4751 RepID=A0A0H1BN67_9EURO |
| A0A1D8PF79_CANAL | 48.33% | 600 | 3e-178 | Glutamate decarboxylase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GAD1 PE=3 SV=1 |
| DCE_YEAST | 44.19% | 559 | 1e-144 | Glutamate decarboxylase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GAD1 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0778
Protein family membership
- Pyridoxal phosphate-dependent decarboxylase (IPR002129)
- Glutamate decarboxylase (IPR010107)
Domains and repeats
-
Domain
-
Domain
1
100
200
300
400
500
571
Detailed signature matches
Protein sequence
>MCA_06508_1 MPLSEHISYEKLLARLEAESPGYSELFRKAAHEIAEGTAEEPDVPENNIFNPYESRYSVTPIPRFRIPQTGSNAESTAQL IRDTLELDGKPALNLASFVNTYIDPIAQRLAAENLNKNMSDNDEYPALMNIHQRCISMIAHLWNVPSGNSAVGTCTTGSS EAIHLGGLAMKRRWEARQKAAGRPFDKPNILMGSNAQVALEKFARYFDVEARIIPVCEESKYTLDLTKIKAALDENTIGI FVILGSTYTGTYEDVKGVSEILDEYEKETGFDIPIHVDGASGAFVAPFCHPDVEWDFRIPRVKSINTSGHKFGLTTAGLG WIIWKDKKYLPDNLVFVLKYLGGDEQSFTLNFSRPGHTVVHQYYNLVSMGFEGYKHVHSSSLYNARLFSKFLEATGYFRC VSNIHRPLGDFGFNPSEKLKHDTTREAAKFNPGLPVVAFTFTDEFKKTYPEIPQAAISTLLRVKGYIIPNYPLPPNSGDI EVLRVVVRYTLTLDLLSKLMGDIVSVVNSLIEAAKSARENPEIPEPDEARHKIHKAILTLVSAPNVEEEHESQWTIDENG VKVRQQHFTVC
GO term prediction
Biological Process
GO:0006536 glutamate metabolic process
GO:0019752 carboxylic acid metabolic process
Molecular Function
GO:0003824 catalytic activity
GO:0004351 glutamate decarboxylase activity
GO:0016831 carboxy-lyase activity
GO:0030170 pyridoxal phosphate binding
Cellular Component
None predicted.