Protein

MCA_06491_1

Length
366 amino acids

Gene name: ARG3

Description: Ornithine carbamoyltransferase

Browser: contigD:4383113-4384214+

RNA-seq: read pairs 5254, FPKM 176.9, percentile rank 86.6% (100% = highest expression)

Protein function

Annotation:ARG3Ornithine carbamoyltransferase
KEGG:K00611OTC ornithine carbamoyltransferase [EC:2.1.3.3]
EGGNOG:0PH0ZARG3ornithine carbamoyltransferase
SGD closest match:S000003624ARG3Ornithine carbamoyltransferase
CGD closest match:CAL0000176534ARG3Ornithine carbamoyltransferase

Protein alignments

%idAln lengthE-value
MIA_02276_181.79%3570.0MIA_02276_1
A0A0J9X6G3_GEOCN71.52%3233e-169Similar to Saccharomyces cerevisiae YJL088W ARG3 Ornithine carbamoyltransferase, catalyzes the sixth step in the biosynthesis of the arginine ornithine OS=Geotrichum candidum GN=BN980_GECA03s07050g PE=3 SV=1
A0A1E3PGT2_9ASCO66.87%3266e-161Ornithine carbamoyltransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52235 PE=3 SV=1
A0A167F4Q8_9ASCO65.43%3242e-154Ornithine carbamoyltransferase OS=Sugiyamaella lignohabitans GN=ARG3 PE=3 SV=1
Q6C924_YARLI65.43%3247e-149YALI0D14894p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D14894g PE=3 SV=1
A0A060SXQ5_BLAAD64.42%3262e-143ARAD1A06336p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A06336g PE=3 SV=1
UniRef50_P1180359.14%3502e-134Ornithine carbamoyltransferase, mitochondrial n=42 Tax=leotiomyceta TaxID=716546 RepID=OTC_EMENI
Q5ABU0_CANAL49.29%3516e-128Ornithine carbamoyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ARG3 PE=3 SV=1
OTC_YEAST50.91%3281e-112Ornithine carbamoyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ARG3 PE=1 SV=1
A0A1E4THW0_9ASCO52.31%2163e-77Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_57622 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9847
Predicted cleavage: 31

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 366

Detailed signature matches

  1. Family IPR006130
    Aspartate/ornithine carbamoyltransferase
    1. PR00100 (AOTCASE)
    2. G3DSA:3.40.50...
    3. PS00097 (CARBAMOYLT...)
    4. SSF53671 (Aspartate...)
  2. Family IPR002292
    Ornithine/putrescine carbamoyltransferase
    1. PR00102 (OTCASE)
    2. TIGR00658
  3. Domain IPR006132
    Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding
    1. PF02729 (OTCace_N)
  4. Domain IPR006131
    Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain
    1. PF00185 (OTCace)

Protein sequence

>MCA_06491_1
MYKSLLLKKPVSKVAQIMVSRSLATKTSSFVPPSPFKHGDAKPRHLLSIDDVTPAELNALVNSAIKHKKIIASGGSAQAA
ANGGLRGQTVPLIFSKRSTRTRVSTEGAVTYLGGHSMFLGKDDIQLGVNESLYDSARVISSMSSAIVARVGPHEDILGLA
EPSRVPVINALSDLFHPFQAITDIMTIREHFAPEDSSLDALKGLKVAWVGDATNVLHDLAIACVKSGIDIAAATPVEYPI
DIDIVEMVRRSGDETGAIFETTHDPKTAIKDADVVVTDTWISMGQEDEAALRMKQFKGYQVTNEMVSAAGAKKHWVFMHC
LPRHPEEVSDEVFYSDRSLVFPEAENRLYAAIAVLESFVVNKGKIL

GO term prediction

Biological Process

GO:0006520 cellular amino acid metabolic process

Molecular Function

GO:0016597 amino acid binding
GO:0016743 carboxyl- or carbamoyltransferase activity

Cellular Component

None predicted.