Protein

MCA_06488_1

Length
396 amino acids

Gene name: ENT1

Description: Epsin-like protein involved in endocytosis and actin patch assembly

Browser: contigD:4378789-4380240-

RNA-seq: read pairs 1637, FPKM 50.9, percentile rank 65.8% (100% = highest expression)

Protein function

Annotation:ENT1Epsin-like protein involved in endocytosis and actin patch assembly
KEGG:K12471EPN epsin
EGGNOG:0PHV8FG08485.1EH domain binding protein epsin 2
SGD closest match:S000002320ENT1Epsin-1
CGD closest match:CAL0000186455orf19.1444Epsin

Protein alignments

%idAln lengthE-value
MIA_02279_166.79%2743e-124MIA_02279_1
A0A060TAC3_BLAAD57.71%2012e-80ARAD1D17556p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D17556g PE=4 SV=1
UniRef50_A0A060TAC357.71%2016e-77ARAD1D17556p n=1 Tax=Blastobotrys adeninivorans TaxID=409370 RepID=A0A060TAC3_BLAAD
A0A0J9X354_GEOCN50.00%2604e-80Similar to Saccharomyces cerevisiae YDL161W ENT1 Epsin-like protein involved in endocytosis and actin patch assembly and functionally redundant with Ent2p OS=Geotrichum candidum GN=BN980_GECA01s07952g PE=4 SV=1
A0A1E3PCG3_9ASCO47.56%1641e-53ENTH-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84594 PE=4 SV=1
A0A161HFX2_9ASCO54.93%1421e-49Ent2p OS=Sugiyamaella lignohabitans GN=ENT2 PE=4 SV=1
Q6C7P2_YARLI54.55%1433e-48YALI0D26510p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D26510g PE=4 SV=1
A0A1D8PGB7_CANAL47.22%1441e-37Epsin OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1444 PE=1 SV=1
ENT1_YEAST45.45%1432e-36Epsin-1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ENT1 PE=1 SV=1
A0A1E4TKZ5_9ASCO46.55%1162e-32Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30596 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9031
Predicted cleavage: 17

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 396

Detailed signature matches

  1. Domain IPR008942
    ENTH/VHS
    1. SSF48464 (ENTH/VHS ...)
    2. G3DSA:1.25.40.90
  2. Domain IPR013809
    ENTH domain
    1. PF01417 (ENTH)
    2. PS50942 (ENTH)
    3. SM00273 (enth_2)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd03571 (ENTH_epsin)
  2. mobidb-lite (disord...)

Residue annotation

  1. Ins(1,4,5)p3 bindi...
  2. PLZF binding site ...

Protein sequence

>MCA_06488_1
MSKHFVRSLKNITNRYTSTEITVRNATSNEPWGPTASELHEIAVLTYHDKYSKEVFAVLEKRLNDKGKNWRHVMKALTIL
LHCIYEGSESVIQWLNRNLYLVKTLREFRYADEKNIDQGGPIRSKAQLITEIIESPEKMALEKQKYRLVREQMGRPGIID
LASGNGAATKSRLTLDMSSNGRPRLSNSGAPVGNQNYTSPKSSLEAGQSSSSYRQKQSNRPPHKASMEGRYSLSLPLQSI
QEETQYNEYSRPSTVVKRKPSVKHFNQIIPPPTTTQLLSGSKSLKINTSLPGDTQQNLSPATLSSNNPFLRELNTGTETS
SSQIPNSIHQNDNYLKKANTEGVKLMRSMSLAASVSPANSSLSDKPLSNSVPSSPNRPTSSHPSSPSTPSQLSVQH

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.