Protein

MCA_06365_1

Length
224 amino acids

Gene name: REX2

Description: Oligoribonuclease, mitochondrial

Browser: contigD:3998027-3998916+

RNA-seq: read pairs 655, FPKM 36.0, percentile rank 57.8% (100% = highest expression)

Protein function

Annotation:REX2Oligoribonuclease, mitochondrial
KEGG:K13288orn oligoribonuclease [EC:3.1.-.-]
EGGNOG:0PNZSFG00388.1oligoribonuclease
SGD closest match:S000004049REX2Oligoribonuclease, mitochondrial
CGD closest match:CAL0000187510REX2Rex2p

Protein alignments

%idAln lengthE-value
MIA_00832_175.81%1864e-107MIA_00832_1
A0A0J9XH47_GEOCN60.42%1924e-89Similar to Saccharomyces cerevisiae YLR059C REX2 3'-5' RNA exonuclease OS=Geotrichum candidum GN=BN980_GECA17s01209g PE=4 SV=1
UniRef50_A0A0J9XH4760.42%1929e-86Similar to Saccharomyces cerevisiae YLR059C REX2 3'-5' RNA exonuclease n=8 Tax=saccharomyceta TaxID=716545 RepID=A0A0J9XH47_GEOCN
A0A1E3PEF6_9ASCO62.22%1802e-89Ribonuclease H-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_53247 PE=4 SV=1
A0A060T3Q0_BLAAD56.57%1982e-85ARAD1A11374p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A11374g PE=4 SV=1
Q6C4G7_YARLI62.36%1786e-82YALI0E26939p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E26939g PE=4 SV=1
A0A1D8PGG3_CANAL58.60%1862e-77Rex2p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=REX2 PE=4 SV=1
ORN_YEAST57.67%1893e-75Oligoribonuclease, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=REX2 PE=1 SV=1
A0A1E4TAV1_9ASCO46.63%1784e-56Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_3548 PE=4 SV=1
A0A167DIL0_9ASCO65.65%1311e-55Rex2p OS=Sugiyamaella lignohabitans GN=REX2 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9962
Predicted cleavage: 41

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 224

Detailed signature matches

  1. Family IPR022894
    Oligoribonuclease
    1. cd06135 (Orn)
  2. Domain IPR012337
    Ribonuclease H-like domain
    1. SSF53098 (Ribonucle...)
    2. G3DSA:3.30.42...
  3. Domain IPR013520
    Exonuclease, RNase T/DNA polymerase III
    1. PF00929 (RNase_T)
    2. SM00479 (exoiiiendus)

Residue annotation

  1. putative substrate...
  2. catalytic site cd0...
  3. putative active si...
  4. dimer interface cd...

Protein sequence

>MCA_06365_1
MLIPFARYNYRFFSTSIPRFALVNKKKYLNRYISMTNNGPLVWIDCEMTGLDYFNDHIIEICCILTDKDLNIIEENGFEA
VIHYPKEIMDNMGAWCVKQHGKSGLTQKVIESTNTREEVETNLLKYLEKHIGRSNYGMLAGNSVHHDRIFMLREFPKVID
YLHYRQVDVSSIKEVGKRHNPKLMMQLPQKAMAHTAKSDILESIKELKWYYDNYLIKPSSSEEK

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0000175 3'-5'-exoribonuclease activity
GO:0003676 nucleic acid binding

Cellular Component

None predicted.