Protein

MCA_06335_1

Length
713 amino acids

Gene name: BPL1

Description: Biotin--protein ligase

Browser: contigD:3890285-3892535+

RNA-seq: read pairs 2667, FPKM 46.2, percentile rank 63.5% (100% = highest expression)

Protein function

Annotation:BPL1Biotin--protein ligase
KEGG:K01942HLCS biotin--protein ligase [EC:6.3.4.9 6.3.4.10 6.3.4.11 6.3.4.15]
EGGNOG:0PI1ABPL1Biotin apoprotein ligase
SGD closest match:S000002300BPL1Biotin--protein ligase
CGD closest match:CAL0000192734CAALFM_CR10620CABiotin--[acetyl-CoA-carboxylase] ligase

Protein alignments

%idAln lengthE-value
MIA_04220_163.41%7270.0MIA_04220_1
A0A0J9X5Q0_GEOCN55.35%7190.0Similar to Saccharomyces cerevisiae YDL141W BPL1 Biotin:apoprotein ligase OS=Geotrichum candidum GN=BN980_GECA02s05268g PE=4 SV=1
UniRef50_A0A0J9X5Q055.35%7190.0Similar to Saccharomyces cerevisiae YDL141W BPL1 Biotin:apoprotein ligase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X5Q0_GEOCN
A0A161HJW8_9ASCO49.32%7380.0Biotin--[acetyl-CoA-carboxylase] ligase BPL1 OS=Sugiyamaella lignohabitans GN=BPL1 PE=4 SV=1
A0A060TDA3_BLAAD47.53%7280.0ARAD1D41668p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D41668g PE=4 SV=1
Q6C416_YARLI42.22%7133e-175YALI0E30591p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E30591g PE=4 SV=1
A0A1D8PUA1_CANAL40.14%7306e-163Biotin--[acetyl-CoA-carboxylase] ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR10620CA PE=4 SV=1
A0A1E4TL04_9ASCO39.42%7231e-154Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_86662 PE=4 SV=1
BPL1_YEAST35.20%7336e-140Biotin--protein ligase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BPL1 PE=1 SV=1
A0A1E3PL45_9ASCO36.40%5114e-83Class II aaRS and biotin synthetase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83010 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0115

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 713

Detailed signature matches

  1. Domain IPR019197
    Biotin-protein ligase, N-terminal
    1. PF09825 (BPL_N)
  2. Domain IPR029062
    Class I glutamine amidotransferase-like
    1. G3DSA:3.40.50...
    2. SSF52317 (Class I g...)
  3. Domain IPR004143
    Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain
    1. PF03099 (BPL_LplA_LipB)
    2. PS51733 (BPL_LPL_CA...)
  4. Domain IPR003142
    Biotin protein ligase, C-terminal
    1. PF02237 (BPL_C)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.30.93...
  2. SSF55681 (Class II ...)
  3. cd03144 (GATase1_Sc...)

Residue annotation

  1. conserved cys resi...

Protein sequence

>MCA_06335_1
MNVLVYSGPGTTVESVKHCTDTLRRLLSPYYAVLNVTSSTLVSEPWQASTSLLVIPGGADLPYCRELDGAGNKQIEKFVR
QGGRYLGLCAGGYYGSGRVEFEVGNREMEVSGPRELKFFPGIARGAVFRGFQYGNHVNAKAAQISITDDLLTSTSDNPTT
TIDKEKLRQVFSYVDGGCLFVDAEKYKSKGVQVLARYLDKLEVSGSDLEEDNIDKTKPAAAVYCKVGRGSAILSGLHPEF
TPDLLKKIPSEKEYSAMIQVLEQHNLSRIEFMKAILLKMGLKVNSTEIPIPGLSRLFLTSLYPPALKHFIDRLREEIGFS
GPQNNLLVCSNDTFRIWNAAQPDRFTTSDQPAEEEEDDLNKIIKDIDVYTTGLPDSRMAGHFNLSSYYSKLRELKAAAYP
MFTSENEHQFTMGATILYGEVVTSTSTMLFQNYKLLKCLPTGFTAVATTQVAGRGRANNVWVNPVGVLPFSTVLRLPMTN
EAGEPTSIVFIQYLAAIAIVNAIKNYARSMLGIDNFPVFIKWPNDVYIVNPFSEKSNSSRVPDLSEAEYQDLFFKVSGIL
VNTTVLDGEYVIVVGIGINVSNAAPSKSLNRLVDEINERVRTPQGKPRYGHFEEEPLLAFFMHIWEDMIRDFRFQGFRAF
EQEYYDKWLHTDKIVTLEQYGNTKAVIKGISSDFGMLIAEEVDRNNKPMGKLFELQPDGNSFDMMKGLLKKKQ

GO term prediction

Biological Process

GO:0006464 cellular protein modification process

Molecular Function

None predicted.

Cellular Component

None predicted.