Protein

MCA_06324_1

Length
642 amino acids

Gene name: NOG1

Description: Nucleolar GTP-binding protein 1

Browser: contigD:3864119-3866048-

RNA-seq: read pairs 4367, FPKM 83.9, percentile rank 76.0% (100% = highest expression)

Protein function

Annotation:NOG1Nucleolar GTP-binding protein 1
KEGG:K06943NOG1 nucleolar GTP-binding protein
EGGNOG:0PFNANOG1Involved in the biogenesis of the 60S ribosomal subunit (By similarity)
SGD closest match:S000006014NOG1Nucleolar GTP-binding protein 1
CGD closest match:CAL0000194572NOG1Nucleolar GTP-binding protein 1

Protein alignments

%idAln lengthE-value
MIA_03319_180.19%6460.0MIA_03319_1
A0A0J9XAU9_GEOCN73.76%6440.0Nucleolar GTP-binding protein 1 OS=Geotrichum candidum GN=BN980_GECA07s02254g PE=3 SV=1
A0A161HEH7_9ASCO70.88%6490.0Nucleolar GTP-binding protein 1 OS=Sugiyamaella lignohabitans GN=NOG1 PE=3 SV=1
A0A060TIA6_BLAAD68.17%6440.0Nucleolar GTP-binding protein 1 OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D45078g PE=3 SV=1
A0A1E3PRX1_9ASCO65.16%6430.0Nucleolar GTP-binding protein 1 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48819 PE=3 SV=1
NOG1_YEAST63.75%6510.0Nucleolar GTP-binding protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NOG1 PE=1 SV=1
UniRef50_Q0289263.75%6510.0Nucleolar GTP-binding protein 1 n=382 Tax=Fungi TaxID=4751 RepID=NOG1_YEAST
Q6CG44_YARLI63.26%6450.0Nucleolar GTP-binding protein 1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B00990g PE=3 SV=1
A0A1D8PKD3_CANAL62.19%6480.0Nucleolar GTP-binding protein 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NOG1 PE=3 SV=1
A0A1E4TAH4_9ASCO62.38%6460.0Nucleolar GTP-binding protein 1 OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_128386 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0397

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 642

Detailed signature matches

  1. Family IPR024926
    Nucleolar GTP-binding protein 1
    1. PIRSF038919 (NOG1)
  2. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  3. Domain IPR005225
    Small GTP-binding protein domain
    1. TIGR00231
  4. Domain IPR006073
    GTP binding domain
    1. PR00326 (GTP1OBG)
  5. Domain IPR031167
    OBG-type guanine nucleotide-binding (G) domain
    1. PS51710 (G_OBG)
  6. Domain IPR010674
    Nucleolar GTP-binding protein 1, Rossman-fold domain
    1. PF06858 (NOG1)
  7. Domain IPR012973
    NOG, C-terminal
    1. PF08155 (NOGCT)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.40.50...
  3. cd01897 (NOG)

Residue annotation

  1. G1 box cd01897
  2. GTP/Mg2+ binding s...
  3. Switch I region cd...
  4. G2 box cd01897
  5. G3 box cd01897
  6. Switch II region c...
  7. G4 box cd01897
  8. G5 box cd01897

Protein sequence

>MCA_06324_1
MQLTWKDIPVIPNSTEFLDVVLNRTQRKTPTVIRPGFKISRIRAFYMRKVRYTGDGFCEKLQEIVESFPNINEIHPFHRD
LLDTLYEKNHYKVSLASLSRAKSLIEQVTRDYVRLLKFGQSLFQCKQLKRAALGRMATIVKRLKDALLYLEQVRQHLSRL
PSIDPNTRTLVICGYPNVGKSSFLRSITRADVEVQPYAFTTKSLYVGHFDYKYLRFQAIDTPGILDRPTEEMTNIEMQSI
YAIAHIRSCILYFMDLSEQCGFSVEDQVKLFHSIQALFLHKNVFVVLNKIDVMRPEDLDEERKALLESMTKLPNVHVEFT
QLSCVTEEGIMEVRNKVCDSLLSSRLEKKKSGSRMASIENKIHISRPQLTDGSMREPFIPEEFRKLKKYDAADPERRKLA
KDIEVENGGAGVFQPNYKDAYILEDEEWKNDIMPEVLNGKNVYDFLDPEIGKKLQELEEEEERLEKEGFYDSDDEDVVDS
EEEEIKEKAEWIRQRHLLIKNKKLANRSLTNRAVIPRKFVKRTVGQMESALSDVGVDTSAVTKKAQAASAGSLKRNKSGA
EVLMGEYSGETKDSARIANKKQQLKQLQGLGSTRTKAERMIKLDQRDRAKFNVAYETEKHKTAALPKHLYTGKRGIGKTQ
RR

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005525 GTP binding

Cellular Component

GO:0005730 nucleolus