MCA_06298_1

Protein

Length

610 amino acids

Gene name: VPS5

Description: Vacuolar protein sorting-associated protein 5

Browser: contigD:3794039-3795872+

RNA-seq: read pairs 4239, FPKM 85.7, percentile rank 76.4% (100% = highest expression)

Protein function

Annotation:		VPS5	Vacuolar protein sorting-associated protein 5
KEGG:	K17917	SNX1_2	sorting nexin-1/2
EGGNOG:	0PI2Z	VPS5	vacuolar protein sorting-associated protein vps5
SGD closest match:	S000005595	VPS5	Vacuolar protein sorting-associated protein 5
CGD closest match:	CAL0000176726	orf19.2867	Sorting nexin 1

Protein alignments

	%id	Aln length	E-value
MIA_06291_1	62.62%	610	0.0	MIA_06291_1
A0A060T0Q6_BLAAD	61.02%	413	2e-172	ARAD1C10230p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C10230g PE=4 SV=1
A0A167CBU5_9ASCO	62.47%	405	6e-165	Vps5p OS=Sugiyamaella lignohabitans GN=VPS5 PE=4 SV=1
UniRef50_A0A167CBU5	62.47%	405	2e-161	Vps5p n=2 Tax=Trichomonascaceae TaxID=410830 RepID=A0A167CBU5_9ASCO
A0A0J9XLL7_GEOCN	52.25%	511	8e-155	Similar to Saccharomyces cerevisiae YOR069W VPS5 Structural component of the retromer membrane coat complex OS=Geotrichum candidum GN=BN980_GECA32s01847g PE=4 SV=1
Q6CGR9_YARLI	52.71%	387	5e-127	YALI0A16797p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A16797g PE=4 SV=1
A0A1E3PM18_9ASCO	51.30%	384	2e-118	Vps5-domain-containing protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_22648 PE=4 SV=1
A0A1E4TCW5_9ASCO	51.23%	367	7e-112	Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_11595 PE=4 SV=1
Q5A1F2_CANAL	38.77%	472	3e-87	Sorting nexin 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.2867 PE=4 SV=1
VPS5_YEAST	37.50%	424	9e-73	Vacuolar protein sorting-associated protein 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VPS5 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1886

Protein family membership

None predicted.

Domains and repeats

Domain
211 - 353
Phox homologous domain (IPR001683)
363 - 594
Sorting nexin Vps5-like, C-terminal (IPR015404)
Domain
381 - 601
Arfaptin homology (AH) domain/BAR domain (IPR027267)

1 100 200 300 400 500 610

Detailed signature matches

IPR001683

Phox homologous domain
1. PF00787 (PX)
  
  224 - 336
  
  Pfam
  PF00787 (PX)
2. PS50195 (PX)
  
  224 - 340
  
  PROSITE profiles
  PS50195 (PX)
3. SM00312 (PX_2)
  
  223 - 337
  
  SMART
  SM00312 (PX_2)
4. G3DSA:3.30.15...
  
  211 - 353
  
  GENE3D
  G3DSA:3.30.1520.10 (G3DSA:3.30.1520.10)
5. SSF64268 (PX domain)
  
  225 - 338
  
  SUPERFAMILY
  SSF64268 (PX domain)
IPR015404

Sorting nexin Vps5-like, C-terminal
1. PF09325 (Vps5)
  
  363 - 594
  
  Pfam
  PF09325 (Vps5)
IPR027267

Arfaptin homology (AH) domain/BAR domain
1. SSF103657 (BAR/IMD ...)
  
  381 - 601
  
  SUPERFAMILY
  SSF103657 (BAR/IMD domain-like)

no IPR

Unintegrated signatures

Coil

496 - 537

COILS
Coil (Coil)
G3DSA:1.20.12...

384 - 595

GENE3D
G3DSA:1.20.1270.60 (G3DSA:1.20.1270.60)
cd06861 (PX_Vps5p)

226 - 337

CDD
cd06861 (PX_Vps5p)
cd07627 (BAR_Vps5p)

380 - 595

CDD
cd07627 (BAR_Vps5p)
mobidb-lite (disord...)

1 - 124

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

phosphoinositide b...

267R

phosphoinositide binding site
267R, 268Y, 269R, 293K, 294Q, 307R
CDD
cd06861 (PX_Vps5p)

268Y

phosphoinositide binding site
267R, 268Y, 269R, 293K, 294Q, 307R
CDD
cd06861 (PX_Vps5p)

269R

phosphoinositide binding site
267R, 268Y, 269R, 293K, 294Q, 307R
CDD
cd06861 (PX_Vps5p)

293K

phosphoinositide binding site
267R, 268Y, 269R, 293K, 294Q, 307R
CDD
cd06861 (PX_Vps5p)

294Q

phosphoinositide binding site
267R, 268Y, 269R, 293K, 294Q, 307R
CDD
cd06861 (PX_Vps5p)

307R

phosphoinositide binding site
267R, 268Y, 269R, 293K, 294Q, 307R
CDD
cd06861 (PX_Vps5p)
dimer interface cd...

391Y

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

394T

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

395L

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

398H

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

399F

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

401Y

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

402L

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

405S

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

408S

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

409V

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

412Q

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

419A

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

420T

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

422E

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

423F

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

426V

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

429S

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

430L

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

433V

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

434E

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

450E

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

557A

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

560E

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

561E

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

563K

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

564A

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

565S

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

568R

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

571I

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

572E

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

574Y

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

575L

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

576E

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

578A

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

579V

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

582Q

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

583K

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

585A

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

586I

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

589W

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

590E

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

592F

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

593Y

dimer interface
391Y, 394T, 395L, 398H, 399F, 401Y, 402L, 405S, 408S, 409V, 412Q, 419A, 420T, 422E, 423F, 426V, 429S, 430L, 433V, 434E, 450E, 557A, 560E, 561E, 563K, 564A, 565S, 568R, 571I, 572E, 574Y, 575L, 576E, 578A, 579V, 582Q, 583K, 585A, 586I, 589W, 590E, 592F, 593Y
CDD
cd07627 (BAR_Vps5p)

Protein sequence

>MCA_06298_1
MVDDELDLAGSHWGDVVSTSSNNEADSNESKPAQENDNDDNSAQSKNKESSATTTSTPSKSKHSRISTLRSSRFNKKSVP
KVHIESVTSSDPLGPLGSSQSDTTSSDSVSAQKTAESERKAYGDKDITTSIKHFNSNNERLALFGNEPSELTSNPFATET
SQNSNQLYNSSVESATAGIAGVSIDDKSSGKPSALNPNAQLNGEQTASLTAASSQPNKSTQLTNTFEVSVGDPIKVGDIT
SAHTVYTVHTKTNSPNFSSSETSVTRRYRDFRWLYHALENNNPGIIIPPPPEKQAVGRFDENFVESRRAALESMINKCVN
HPILQNDPDLRIFLESETFSTDIKSKQYQAQNTSVSGGSESKGFMSSLGGAFSFSGKYVETDEWFIQKKNYVDTLENHFR
YLSKSLESVVTQRNELSDATSEFSIVLNSLSQVELSKSFGELIERFSDVETRIRDLYYRQCMQDVLSLGTTLDEYIRLLT
SIRNVFAQRQKSYFAMQSAEQELTKKRQHLEKVMKQGKTLQDKIAILRDEVVEQEKKVLNARVAFDDISKSIIKEFARFE
ESKASDFRNSIELYLENAVEAQKEAIEIWETFYQLSGFIPVSSDPEATKV

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0035091 phosphatidylinositol binding

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features

MCA_06298_1

Protein function

Protein alignments

Mitochondrial localization by mitoprotII

Protein family membership

Domains and repeats

Detailed signature matches

Residue annotation

Protein sequence

GO term prediction

Biological Process

Molecular Function

Cellular Component