Protein

MCA_06293_1

Length
317 amino acids


Gene name: NOP1

Description: rRNA 2'-O-methyltransferase fibrillarin

Browser: contigD:3782612-3783566+

RNA-seq: read pairs 7293, FPKM 283.4, percentile rank 91.4% (100% = highest expression)

Protein function

Annotation:NOP1rRNA 2'-O-methyltransferase fibrillarin
KEGG:K14563NOP1 rRNA 2'-O-methyltransferase fibrillarin [EC:2.1.1.-]
EGGNOG:0PIJ4NOP1rRNA methyltransferase NOP1
SGD closest match:S000002172NOP1rRNA 2'-O-methyltransferase fibrillarin
CGD closest match:CAL0000195815NOP1rRNA methyltransferase

Protein alignments

%idAln lengthE-value
MIA_06301_192.59%2432e-161MIA_06301_1
FBRL_YEAST86.42%2438e-155rRNA 2'-O-methyltransferase fibrillarin OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NOP1 PE=1 SV=1
UniRef50_P1564686.42%2432e-151rRNA 2'-O-methyltransferase fibrillarin n=417 Tax=Eukaryota TaxID=2759 RepID=FBRL_YEAST
A0A167ESL0_9ASCO83.13%2435e-153rRNA methyltransferase NOP1 OS=Sugiyamaella lignohabitans GN=NOP1 PE=3 SV=1
A0A1E3PJ78_9ASCO83.61%2442e-152Fibrillarin OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83393 PE=3 SV=1
A0A060TBK1_BLAAD84.36%2431e-151ARAD1D32450p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D32450g PE=3 SV=1
Q6CBS8_YARLI84.36%2432e-151YALI0C15873p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C15873g PE=3 SV=1
A0A0J9XH22_GEOCN82.79%2442e-150Similar to Saccharomyces cerevisiae YDL014W NOP1 Nucleolar protein OS=Geotrichum candidum GN=BN980_GECA16s02012g PE=3 SV=1
A0A1E4TGH9_9ASCO85.12%2422e-150Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_31674 PE=3 SV=1
Q5A0V9_CANAL83.95%2432e-149rRNA methyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=NOP1 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9978
Predicted cleavage: 83

Protein family membership

Domains and repeats

1 50 100 150 200 250 317

Detailed signature matches

    1. PIRSF006540 (Nop17p)
    2. MF_00351 (RNA_methy...)
    3. SM01206 (Fibrillarin_2)
    4. PF01269 (Fibrillarin)
    5. PR00052 (FIBRILLARIN)
    1. SSF53335 (S-adenosy...)
    1. PS00566 (FIBRILLARIN)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MCA_06293_1
MAFGQSRGGGRGAPRGGSRGGFRGGRGGGAGGRGAPRGGGFRGGRGGGGRGAPRGGARGGRGGISKGGPRGGAKVIVEPH
RHAGIFIARGKEDLLVTKNMAPGESVYGEKRITVETSSSKNDSEEPTTTKTEYRVWNPFRSKLAAGVLGGIDEIFIAPGK
KVLYLGAASGTSVSHVSDIVGPEGVVYAVEFSPRSGRDLIAMAQKRPNVIPIIEDARHPQKYRMLVGMVDAVFADVAQPD
QARIIALNSHLFLKDKGGVIISIKANCIDSTVDAETVFAREVQKLREERIKPLEQLTLEPYERDHCIVIGRYMRSAK

GO term prediction

Biological Process

GO:0006364 rRNA processing
GO:0008033 tRNA processing

Molecular Function

GO:0003723 RNA binding
GO:0008168 methyltransferase activity

Cellular Component

None predicted.