Protein

MCA_06280_1

Length
864 amino acids


Description: Cullin-4 -like protein; ubiquitin ligase subunit

Browser: contigD:3748556-3751209+

RNA-seq: read pairs 1522, FPKM 21.7, percentile rank 43.6% (100% = highest expression)

Protein function

Annotation:Cullin-4 -like protein; ubiquitin ligase subunit
KEGG:K10609CUL4 cullin 4
EGGNOG:0PGFAFG05520.1ubiquitin ligase subunit CulD
SGD closest match:S000003235CUL3Cullin-3
CGD closest match:CAL0000191783RTT101Cullin

Protein alignments

%idAln lengthE-value
MIA_06404_126.06%4959e-37MIA_06404_1
UniRef50_F2U0F829.37%2864e-23Putative uncharacterized protein n=1 Tax=Salpingoeca rosetta (strain ATCC 50818 / BSB-021) TaxID=946362 RepID=F2U0F8_SALR5
A0A167EDC6_9ASCO26.05%3573e-23Cullin CUL3 OS=Sugiyamaella lignohabitans GN=CUL3 PE=3 SV=1
A0A0J9XCA7_GEOCN25.39%3822e-19Similar to Saccharomyces cerevisiae YGR003W CUL3 Ubiquitin-protein ligase OS=Geotrichum candidum GN=BN980_GECA09s00296g PE=3 SV=1
A0A060TBE1_BLAAD24.94%4091e-17ARAD1D34496p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D34496g PE=3 SV=1
Q6C9B4_YARLI24.31%3259e-12YALI0D12518p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D12518g PE=3 SV=1
CUL3_YEAST27.09%2031e-10Cullin-3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CUL3 PE=1 SV=1
A0A1E3PTF5_9ASCO28.82%1702e-09Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_39506 PE=3 SV=1
A0A1E4TJE3_9ASCO22.40%3174e-08Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_78572 PE=3 SV=1
A0A1D8PDR1_CANAL31.34%2016e-08Cullin OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RTT101 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1968

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
1 100 200 300 400 500 600 700 800 864

Detailed signature matches

    1. PF00888 (Cullin)
    1. SSF75632 (Cullin ho...)
    2. PS50069 (CULLIN_2)
    3. SM00182 (cul_2)
    1. SSF46785 ("Winged h...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MCA_06280_1
MSVSNKRRKNNYSPDFTIATSRFSHANSGMNRDTDRNHLASYDTSSDSLSSTSSSVSLPLYRAPRHRVITLQNLNKRQKR
QIRIIPSEPSTAPPDATTFFIKEQESNIRNFIEAVFSLDRAENVQSSVAIDENTEVIVKMGHIYAQELWKTVADLLKQQI
SLLGKQLKDRLKDAANFTFDQAKETLEFFKRVFFLFTSAQKMVSSALSYLDLAYVRIKTGFANGINSYMILEFARYFDDT
HFIKDMSLVINIIIQSSLSSTIIDNGLSAQVSQQFESSYHQVMEDYYFLRENLEKISPTASAKMAKILCQLEPSVVISLT
SLLNQDEITAQDLVASIHDLVNFFRTRIISESVKPNYLTFSENKIRSMVAEKWKEKLCSNLADYLEESKLSNYEKIFYFF
YEDSSRQFFSEKLSADLNLLLRNILTQQISSEVQIERISKIRKNLTKVSEQSFGFISEREKDVLNKMFRSSWNAFICDGD
KMDYISKASEAYLDRILKDKSMDPSRVDSIIESVIYLFKYLSTYGKDNFVNRFKTSLNKRLLQDKAYFFEKEEEIINEIG
KEMGAEHIESLSSMIADMKISETLSEAFKPKMRLINPKISFAAKILNEKNWPKPRDIEFTLPASLSSIQNSFTKFYKAYE
PQNNPEKANYKNRKLTWAPVRHKFLLKVNLNQGAKQIFANTLQATILLLFDESPEDRKYTLSMKDIIQETNIPLPDLEGA
LTSLVYGKYNILLRLAPGSLEPIPKSVPYDKDDVYKVNLGLTSSKLRINLNLSIPNETPLGNVRDEGKLDMSLKMEASVV
FCMKQNREMTSLELKSKVCEDLVKYVKNENEINLDDLDKIIDKMIEKGYIDRHHSSPSTYVYVP

GO term prediction

Biological Process

GO:0006511 ubiquitin-dependent protein catabolic process

Molecular Function

GO:0031625 ubiquitin protein ligase binding

Cellular Component

None predicted.