Protein

MCA_06262_1

Length
325 amino acids

Gene name: SCS2

Description: Vesicle-associated membrane protein-associated protein SCS2

Browser: contigD:3711415-3713733+

RNA-seq: read pairs 7955, FPKM 301.5, percentile rank 91.8% (100% = highest expression)

Protein function

Annotation:SCS2Vesicle-associated membrane protein-associated protein SCS2
EGGNOG:0PNHZSCS2Integral ER membrane protein
SGD closest match:S000000922SCS2Vesicle-associated membrane protein-associated protein SCS2
CGD closest match:CAL0000179063orf19.1212Phosphatidylinositol-binding protein

Protein alignments

%idAln lengthE-value
MIA_05187_166.41%1312e-58MIA_05187_1
A0A0J9X2P2_GEOCN51.30%1541e-40Similar to Saccharomyces cerevisiae YER120W SCS2 Integral ER membrane protein that regulates phospholipid metabolism via an interaction with the FFAT motif of Opi1p OS=Geotrichum candidum GN=BN980_GECA01s08425g PE=4 SV=1
UniRef50_A0A0J9X2P251.30%1543e-37Similar to Saccharomyces cerevisiae YER120W SCS2 Integral ER membrane protein that regulates phospholipid metabolism via an interaction with the FFAT motif of Opi1p n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X2P2_GEOCN
A0A1D8PQC2_CANAL47.62%1267e-33Phosphatidylinositol-binding protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1212 PE=4 SV=1
SCS2_YEAST47.62%1262e-28Vesicle-associated membrane protein-associated protein SCS2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SCS2 PE=1 SV=3
Q6CA74_YARLI43.88%1393e-27YALI0D05291p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D05291g PE=4 SV=1
A0A167E5N5_9ASCO38.04%1631e-26Phosphatidylinositol-binding protein SCS2 OS=Sugiyamaella lignohabitans GN=SCS2 PE=4 SV=1
A0A1E3PHX2_9ASCO37.69%1307e-24Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46812 PE=4 SV=1
A0A060T3Q6_BLAAD43.75%1281e-23ARAD1A11484p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A11484g PE=4 SV=1
A0A1E4TL77_9ASCO41.60%1253e-22Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_87380 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0057

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 325

Detailed signature matches

  1. Family IPR016763
    Vesicle-associated membrane-protein-associated protein
    1. PIRSF019693 (VAMP_a...)
  2. Domain IPR008962
    PapD-like
    1. SSF49354 (PapD-like)
  3. Domain IPR000535
    Major sperm protein (MSP) domain
    1. PS50202 (MSP)
    2. PF00635 (Motile_Sperm)
  4. Domain IPR013783
    Immunoglobulin-like fold
    1. G3DSA:2.60.40.10
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. Coil
  3. NON_CYTOPLASM... (N...)
  4. TMhelix
  5. TRANSMEMBRANE (Tran...)
  6. mobidb-lite (disord...)

Protein sequence

>MCA_06262_1
MEISPKTLEFSSPFTIQSHTSVVIRNNTDQRYAFKVKTTAPKRYFVRPNASIVEPGETQSVSIILQPYEEELPEDYKCND
KFLVMQCEAPNEVTMENFAEFWSLQEHAPNSKMSNKKIRVHYDIRPTHEIPGLIEARKAGMSGGQVRGSDGSPEHYDEQG
AGGFDGSSSISSQNAAASVVSGNSVPAESAPQVPVHSQFEQGYQQEQPQPINPIAQESKSDFGRSDDTHLSEAVNKASDK
IKAFSEELNQEKATAFGTTTSNKPSTSEYNEKSAFSSSTPASNNKNAISQTSVTAKKILERNNEIPLPYVVLLVIISFLI
GWFFF

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

GO:0005789 endoplasmic reticulum membrane