Protein

MCA_06250_1

Length
756 amino acids

Gene name: ORC5

Description: Origin recognition complex subunit 5; P-loop containing nucleoside triphosphate hydrolase

Browser: contigD:3678657-3680928+

RNA-seq: read pairs 883, FPKM 14.4, percentile rank 33.2% (100% = highest expression)

Protein function

Annotation:ORC5Origin recognition complex subunit 5; P-loop containing nucleoside triphosphate hydrolase
EGGNOG:0PHS0PGUG_01612Origin recognition complex subunit
SGD closest match:S000005205ORC5Origin recognition complex subunit 5
CGD closest match:CAL0000191350CAALFM_CR06960WAOrigin recognition complex subunit 5

Protein alignments

%idAln lengthE-value
MIA_03020_137.68%4226e-87MIA_03020_1
A0A0J9XK87_GEOCN56.02%1913e-60Similar to Saccharomyces cerevisiae YNL261W ORC5 Subunit of the origin recognition complex OS=Geotrichum candidum GN=BN980_GECA25s00824g PE=4 SV=1
UniRef50_A0A0J9XK8756.02%1915e-57Similar to Saccharomyces cerevisiae YNL261W ORC5 Subunit of the origin recognition complex n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XK87_GEOCN
A0A167C375_9ASCO56.18%1782e-57Origin recognition complex subunit 5 OS=Sugiyamaella lignohabitans GN=ORC5 PE=4 SV=1
A0A060T9V0_BLAAD54.49%1789e-53ARAD1D21890p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D21890g PE=4 SV=1
A0A1E3PCY1_9ASCO50.56%1784e-49Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_29026 PE=4 SV=1
Q6CG25_YARLI45.51%1787e-40YALI0B01452p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B01452g PE=4 SV=1
Q59SM3_CANAL26.34%2242e-18Origin recognition complex subunit 5 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR06960WA PE=4 SV=1
ORC5_YEAST30.34%1783e-18Origin recognition complex subunit 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ORC5 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.4186
Predicted cleavage: 13

Protein family membership

Domains and repeats

  1. Domain
1 100 200 300 400 500 600 700 756

Detailed signature matches

  1. Family IPR020796
    Origin recognition complex, subunit 5
    1. PF14630 (ORC5_C)
  2. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:3.40.50...
  3. PF13191 (AAA_16)
  4. mobidb-lite (disord...)

Protein sequence

>MCA_06250_1
MQRFIPKDDLERIKAKVPCRNNQLSLLDSFLFAKPPVIHVNGVTSTGKTLLLRTIFEETKADYIWVNSEQCSTIRILLQR
ALREVKALLTERYPPEFSQNDEETLEEKLRQLLKSATHVVHGNTAFDVVAEHFPGFAVLFKAFIDFFNYQKTSGRHIYLV
LDRIDQLPDNVNDLYSCFTRIREMAPKIDCLTTIFVTSSMEPRPLILSYVPHVKFTPYSTAETNKILVDWGKSERARFHE
IYMKSKTEFQEQEAQLIDPALSVSNSIDSTPITTPTKNKKLHSRDALNMMTRNGSNGTVKLTEREAIFELAQIKKSNICI
LPSYCLDAKRAEFQQHNFWDRFCGILITGLNSYTGSDIRLLKDIAIRVWPAFIYPVLTGKHTVTEFRSLWREGRQLFETE
MAITDTLIYKSLDPLENADEERLKRVYREYNRRIAALKSQIENSGHVDTRAGASGSTAIANDLMVSARSPTKRDNGAPIV
TKKRKSDVLMAEVNGADIELPHLPAQKSTKAKPNSDDEADEENKKNNEDEEENEDDVVLISSKEQIDSTADDLFPQMVYR
RPNKRSIIPLNQVSKDMNELPLQSKFILCAGYLASYNPPRFDIRFFSRAKEVRGKRRDTGRRKALKINPRLLAAPAFDME
RMLAILHAIAPTAGSVGYEEDYNDNSNDGEYDENGKAVKKKMRQFENPYQDRLGGFPNNIDIGVQIATLTTLRLMICLNP
SDTLDSKTRWKINTTWPLIKKFSDEIQLDIENFLME

GO term prediction

Biological Process

GO:0006260 DNA replication

Molecular Function

None predicted.

Cellular Component

GO:0000808 origin recognition complex
GO:0005634 nucleus