Protein
MCA_06244_1
Length
1,197 amino acids
Gene name: ARK1
Description: Serine/threonine protein kinase Ark1; in S. cerevisiae involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis.
Browser: contigD:3657519-3661380-
RNA-seq: read pairs 3575, FPKM 36.9, percentile rank 58.5% (100% = highest expression)
Protein function
| Annotation: | ARK1 | Serine/threonine protein kinase Ark1; in S. cerevisiae involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis. | |
|---|---|---|---|
| KEGG: | K08853 | AAK | AP2-associated kinase [EC:2.7.11.1] |
| EGGNOG: | 0PHC9 | FG05586.1 | serine threonine protein kinase |
| SGD closest match: | S000004965 | ARK1 | Actin-regulating kinase 1 |
| CGD closest match: | CAL0000183416 | PRK1 | Actin-regulating kinase PRK1 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_05118_1 | 55.82% | 636 | 0.0 | MIA_05118_1 |
| A0A0J9XDB8_GEOCN | 55.41% | 444 | 2e-154 | Similar to Saccharomyces cerevisiae YNL020C ARK1 Serine/threonine protein kinase involved in regulation of the cortical actin cytoskeleton OS=Geotrichum candidum GN=BN980_GECA10s02331g PE=4 SV=1 |
| UniRef50_A0A0J9XDB8 | 55.41% | 444 | 4e-151 | Similar to Saccharomyces cerevisiae YNL020C ARK1 Serine/threonine protein kinase involved in regulation of the cortical actin cytoskeleton n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XDB8_GEOCN |
| A0A060TCY2_BLAAD | 50.51% | 491 | 8e-151 | ARAD1D43208p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D43208g PE=4 SV=1 |
| A0A167C559_9ASCO | 49.39% | 488 | 5e-144 | Serine/threonine protein kinase ARK1 OS=Sugiyamaella lignohabitans GN=ARK1 PE=4 SV=1 |
| W0TYM4_YARLI | 63.29% | 286 | 1e-123 | YALI0E22847p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E22847g PE=4 SV=1 |
| A0A1E3PEV1_9ASCO | 59.23% | 336 | 3e-128 | Kinase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_72165 PE=4 SV=1 |
| ARK1_YEAST | 56.54% | 306 | 2e-111 | Actin-regulating kinase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ARK1 PE=1 SV=1 |
| PRK1_CANAL | 53.25% | 308 | 4e-99 | Actin-regulating kinase PRK1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PRK1 PE=1 SV=2 |
| A0A1E4TLD6_9ASCO | 53.85% | 286 | 1e-96 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_11892 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0840
Predicted cleavage: 59
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
200
400
600
800
1000
1197
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
mobidb-lite (disord...)
Protein sequence
>MCA_06244_1 MPQTPPPGAYPPGTQLVVGSHNAVIKNFLSVGGYAHVYVVYMNPPFADGNPIACLKRVMVPDKVQLNLLRAEVSAMQRLD GHPNIVKYVDSHAARMATGVGYEVFVLMEYCSGHGLLDFMNAHLRDLLSETQILQIASDIGSGLAYMHYQDPPLIHRDLK IENVLISGDGVFKLCDFGSASPILRPPRNAQEYQMLEHDLQNRTTVQYRSPEMVDISRGFPIDEKSDIWAFGVFIYKLCY YTTPFEKGGDLAILNAKFTFPSKPNFSDRLKRLICATLSEDPRNRPNIYAVLKEIYDMRGLKLNLKDVYVSPTSTQHQNS PESPSKAQSSSNSLSTTPSDSSMSLPQNQNQNIPVQRGVVPIIPPKPMETPKIPTVSPMYRGRPQNNVDPAGVQSTQGNL TDPFSATENQVGTDTNFELSDQELDFEKFNAENVTSKYPTIEELTMSLEKQSLNYTPNAPSSTFSSSTPSVAPIATPLPI PSKPGNSYSSKSLVNLSASASASFDPSQPLPSTSPWLGAQSYSNSNVPSISPTPKIQVNYSQASPVQGYTFAQSPPQNQQ SNAYVSHASQTVPLNQQQQPYSKPTMVSQGVMTSPVASRSHTPAASKEKRTSRYSSSSTSTSNSSSSDDDAVVDGIPRGR SSYASLKDNSRLSYTPQTSSNQNWNQRQPEEVSKPRPVSMYMQSSDSLLDFGDYESQKPPVPPPHLVLPKTKSSSQLQQK NDVLIEPIQTDEKDKLKSLLTGLSAKSSLMVFDNKDDGYIENSVDFLKALDNDHTGRSRHNRSPSGGGSNRMEEQKRNVS HSKKSSVSLKKIGDALKKFDSTGNRSTSYSRNHHYSDNYHKGNTLSNMKKNRFSYSSDSLGTYGSEADDYSSSGGPSPSY DKFPALGRHPSSGRSSSGARGSSSIHSRIQALMNHRTSPPPVKTASGYGKYTDSNSGSSSGSGDDEFGVPVAHAKSYSGN MVKTHYRRASNSLDLPRDNSIAEPTSRYNVPKIDQKTVQKMKDFSSGGGSTKANSQNEMASDESDEQINMSTSKLSRSKT VDASSSRARRLKRPLEFHHKRQLSTISSASSSTEGSSLSNSSNPSRKPPLKPSKPAHLKSPKRVDSGLSPMTASENTITE ASDVQENLPYFDQGEKYSEIQLGKQNSNAAQAQRQSAPSNSTGSNLIDITPSQSPVVGNGNTDDWKDLFNRKYPNVA
GO term prediction
Biological Process
GO:0006468 protein phosphorylation
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Cellular Component
None predicted.