Protein

MCA_06239_1

Length
2,159 amino acids

Gene name: BCK1

Description: Serine/threonine-protein kinase BCK1/SLK1/SSP31; in S. cerevisiae MAPKKK acting in the protein kinase C signaling pathway.

Browser: contigD:3643752-3650357+

RNA-seq: read pairs 1522, FPKM 8.7, percentile rank 23.7% (100% = highest expression)

Protein function

Annotation:BCK1Serine/threonine-protein kinase BCK1/SLK1/SSP31; in S. cerevisiae MAPKKK acting in the protein kinase C signaling pathway.
KEGG:K11229BCK1 mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
EGGNOG:0PG0DPGUG_03900kinase kinase kinase
SGD closest match:S000003631BCK1Serine/threonine-protein kinase BCK1/SLK1/SSP31
CGD closest match:CAL0000184306BCK1Mitogen-activated protein kinase kinase kinase

Protein alignments

%idAln lengthE-value
MIA_05122_185.51%4210.0MIA_05122_1
A0A0J9X866_GEOCN79.04%3960.0Similar to Saccharomyces cerevisiae YJL095W BCK1 Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinase C signaling pathway, which controls cell integrity OS=Geotrichum candidum GN=BN980_GECA05s00263g PE=4 SV=1
UniRef50_A0A0J9X86679.04%3960.0Similar to Saccharomyces cerevisiae YJL095W BCK1 Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinase C signaling pathway, which controls cell integrity n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X866_GEOCN
Q6C2D2_YARLI66.75%3912e-168YALI0F08855p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F08855g PE=4 SV=2
A0A060TAE4_BLAAD63.85%3905e-161ARAD1C45166p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C45166g PE=4 SV=1
A0A1E3PKR3_9ASCO72.16%3342e-167Kinase-like protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_58712 PE=3 SV=1
A0A1E4TDZ2_9ASCO64.84%3101e-141Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_25731 PE=3 SV=1
BCK1_YEAST51.52%3962e-124Serine/threonine-protein kinase BCK1/SLK1/SSP31 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BCK1 PE=1 SV=1
A0A1D8PR87_CANAL54.84%3413e-118Mitogen-activated protein kinase kinase kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=BCK1 PE=4 SV=1
A0A161HJI5_9ASCO65.96%2358e-87Mitogen-activated protein kinase kinase kinase BCK1 OS=Sugiyamaella lignohabitans GN=BCK1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3277

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 200 400 600 800 1000 1200 1400 1600 1800 2000 2159

Detailed signature matches

  1. Domain IPR013761
    Sterile alpha motif/pointed domain
    1. SSF47769 (SAM/Point...)
  2. Domain IPR001660
    Sterile alpha motif domain
    1. PS50105 (SAM_DOMAIN)
  3. Domain IPR011009
    Protein kinase-like domain
    1. SSF56112 (Protein k...)
  4. Domain IPR000719
    Protein kinase domain
    1. PS50011 (PROTEIN_KI...)
    2. SM00220 (serkin_6)
    3. PF00069 (Pkinase)
  5. SITE IPR017441
    Protein kinase, ATP binding site
    1. PS00107 (PROTEIN_KI...)
  6. SITE IPR008271
    Serine/threonine-protein kinase, active site
    1. PS00108 (PROTEIN_KI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.10.15...
  3. G3DSA:1.10.51...
  4. G3DSA:3.30.20...
  5. mobidb-lite (disord...)

Protein sequence

>MCA_06239_1
MSSTPLSNSKHLQLPSQSIEFSKSSPSPSSSTSSLAPSPNLLQTSNSLATKSIPSSLILDSSVPLQSSSADSLHGLHSTS
SMARPPRKSFSVLDRDRETQSERVSVSRSFSDGQPLSVTPNPSFKSSNSSSPVIRSPKLKTSSSFSSNKSLSDGVSNPIS
SNSSSKSNSSLSLQTHNPPESRKSSSQDRPPLGPSIYMNNTTSTSHRNVQIIQSSVSKPSPTSSPSSNEESPVSASPTNN
SASLPTSINHSSTSSSAHSQNDSLDSKVTAEMDITSTSTGPITPSEKTFDPASSDIASTTPSLPSQSVFTPLSPSANIAP
RSRNTSGQHVAYPNPMQCINFRANDPAEWTLDRVSMWLEYNKFGPDWIETFRAKNIHGKEFLSLVSYQKLKDLGPLSTTN
DIYDTHPYRFIRILRKVFDKSSSTTSTIISTTDQNQSSDETTPTQTTASSNDLISSSIQSTDTKTAPTGSSTLETQVKPL
RAPIGNNAETVSELDATKLRVRSRTNPPRPVSVVDPATKAQPSPSSPTTFSNLFSRKHTKSSSSESSFTGNTVHPTSSLN
ILSTTQEEKFDKKSGGGFLGKLRRRDKDGSKDRLRTTKSATNLLDSQSQNSPDNLTPSKSISSSVAPTITFLNSKFDPVR
PKISSRLALLTVNNEFYTVVNLSEASTLEEAKILMTNKLSLEDWSLCSFHLTDFGCTEGQMLDDATLTELIFHPSKYDPS
PNFILKLFIGYNPKYESVSPGQMSMGYDFQPKFHSTFASSEALKSDSDHDLERKSTKGDEGVDPKSKIILVNDSKPIHEE
IVDRLPTDYHDNINDHYRKHSDVASINSHVSLLSQQQASFQQYIKSINHLSGKGNRSRNSSNATSHKLSVSEEHYRDPMR
SSIASIDYSGRRSSEDSFKVIRPERREINFDDRRSSPYDRRGSSVSGLAAERKKSISSSNTLPVPNTTHTSITVPTSSSF
TADKSVPKVSKHTATNVINTTSSTNGIDTANHTQVSRQRSNRRTTALIPLRAAPPPPTRTNANPAPTPIPETTSTNVNTV
SANSPQITQKPQLSRASVIPRGTSRGNRTPSGSKHQVTDSTGEFDTNSEYSESIRSRRNSDTSSKRSIDSSLRRITSEYL
HETPLPPLPPEAESDRVKEAEARRKRKKERSRVRKEKEKQKLKENEEQDLTEEQNENEEEPKTPTEPSSSHDDFDKRSSL
SRSRSNHLTISIEPPRLDLNDLGSPGLSKDLEIFGVLNVPDNNKFLKPSYLSSVKEEDPPSPKSPAVQLFQPAANLPLPA
SSTVSDTTVVPVSTTDPSVDMASTSVSSSATNSNVTISRTVSTNLGPPSRANSTRLRGGLGRNTSSSSVRRNRMREEAKF
HENEISFEGAPALEDSDSSSSDEGLWAKKPPATTVQTTVKQSSQNSNDFSNDIPLNNLSTSSIPDSRKNSLTSLSSIPLS
VQSSYSKSRMRPNLHLDISNNSAVSSSSATRTPSTGITSDQDTPNTSKSSAQQSNHPMSFADIKLGGWAVRPPAEVVYEN
LERFFPDADLDRPIILDPQGVSPPSSPASETTPPPLPSSVSKSRHNSYQPPLSPVVEPSKCEAHFEDALENSSHSPPIEY
HDAEEMPTSSSLHHSSAYQNSSGMTKSQSGNNLKNNMAGLQTPHIGYPKSRQSSITKSISITPSKHIHEYNNHHRHIRKI
LKRVNKANGENVEGTDTDDTDNDEDGKNGNSSVQASQHDDYPENDDQKAMYSNEVDFSNYVNKNGGPQDRKAKLSMRTKS
LRIVVQEATERRKRFQSLANLNSKEAINGPGAPNGVVAGGSPGVLLRRKSTKMWGQKVVEVKPNEFRNGASGGSQQLSRL
RDNRGKVKRFVWVKGELIGKGTFGKVYLALNATAGEMIAVKQVEVPQTLSDKNSERQKEVIDALYAEVETMKDLDHFNIV
QYLGFEALPDSYNLFLEYVPGGTVGMALRKHGRFEISVSQYFTRQVLDGLAYLHSCGILHRDLKSDNILIDLDGVCKISD
FGISKKSRNIYANDAEMSMQGTIFWMAPEVIHNVIDNEKQGYSAKVDIWSLGCVVLEMFAGRRPWSTDEAIGAMYKLGNA
RLAPPIPEDTKPFVTDTGKDFLNQCFEIDPEKRPTAKKLLDHEFCVVDPNFRFSDTKLGKMIRVDDNEKMKKQESKLKK

GO term prediction

Biological Process

GO:0006468 protein phosphorylation

Molecular Function

GO:0004672 protein kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding

Cellular Component

None predicted.