Protein
MCA_06237_1
Length
872 amino acids
Gene name: FZO1
Description: Mitofusin FZO1
Browser: contigD:3639603-3642303-
RNA-seq: read pairs 2040, FPKM 28.9, percentile rank 51.7% (100% = highest expression)
Protein function
| Annotation: | FZO1 | Mitofusin FZO1 | |
|---|---|---|---|
| KEGG: | K06030 | MFN2 | mitofusin 2 [EC:3.6.5.-] |
| EGGNOG: | 0PHSB | FZO1 | Transmembrane GTPase fzo1 |
| SGD closest match: | S000000383 | FZO1 | Mitofusin FZO1 |
| CGD closest match: | CAL0000175191 | FZO1 | Mitofusin |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_05120_1 | 73.21% | 825 | 0.0 | MIA_05120_1 |
| A0A0J9X960_GEOCN | 66.16% | 795 | 0.0 | Similar to Saccharomyces cerevisiae YBR179C FZO1 Mitofusin, integral membrane protein involved in mitochondrial outer membrane tethering and fusion OS=Geotrichum candidum GN=BN980_GECA05s00230g PE=3 SV=1 |
| UniRef50_A0A0J9X960 | 66.16% | 795 | 0.0 | Similar to Saccharomyces cerevisiae YBR179C FZO1 Mitofusin, integral membrane protein involved in mitochondrial outer membrane tethering and fusion n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X960_GEOCN |
| A0A060T4X4_BLAAD | 53.16% | 807 | 0.0 | ARAD1C45210p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C45210g PE=3 SV=1 |
| A0A167DG68_9ASCO | 49.94% | 839 | 0.0 | Mitofusin OS=Sugiyamaella lignohabitans GN=FZO1 PE=3 SV=1 |
| A0A1E3PKQ8_9ASCO | 44.62% | 818 | 0.0 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46567 PE=3 SV=1 |
| Q6C2D0_YARLI | 45.77% | 815 | 0.0 | YALI0F08899p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F08899g PE=3 SV=1 |
| Q59P94_CANAL | 43.73% | 814 | 0.0 | Mitofusin OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=FZO1 PE=3 SV=1 |
| A0A1E4TGI7_9ASCO | 42.25% | 677 | 4e-167 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_20511 PE=3 SV=1 |
| FZO1_YEAST | 34.38% | 832 | 3e-136 | Mitofusin FZO1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FZO1 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0032
Protein family membership
- Dynamin superfamily (IPR022812)
Domains and repeats
-
Domain
1
100
200
300
400
500
600
700
800
872
Detailed signature matches
no IPR
Unintegrated signatures
-
CYTOPLASMIC_D... (C...)
-
-
-
NON_CYTOPLASM... (N...)
-
TRANSMEMBRANE (Tran...)
-
mobidb-lite (disord...)
Protein sequence
>MCA_06237_1 MSFNGFKPHKNDEDEDKIVNPRNGGDHASDSGYGGSIGSDFGNNDPHSASEHLQPNRATYERGTSNLSHHRSPSTSTRRH VMSQVNQLQYNDNRVALGRSISAVLSMLKELQSRNKKWPIYYPASPTSQTEEFKLNRRATLAAVESQSHDDFMSESLKRR TSGGFDTLEHKPAQPKPKQEPRLVPPQLANDFNIFKLDFKIGGLNSTELISQLEKTSVASLLDDKIIRAMRHLLSLRERI DDTTSKVLITGDLNAGKSTFCNALLRRKLLPEDQQPCTSVFCEVIDGRENNGVEEVHAVPVGVKYDRSDDSTYTVFQLKD LEDLVSEYQKYSILKVYVNDRRPVDQSLLRNGVVDICLIDAPGLNMDSYQTTQVFSRQEEIDLVVFVVSAENHFTLSAKE FIYSAANEKSLVFIVVNRFDNIRNKEKCQKSILDQVASLSPETHKDARDFVHFVSSSEVLGDVPDDDNGGGDGPGGDDGN NGHEHPDFDRLEASLRNFVLEKRSLSKLMPAKTYLKNILKDLEALSNVNIQVAETEKNQILKDLDELTPQFEESMKKSVQ ISETMDTKIEEIGQEVYDFTKNHLTKITNEIGESPVTEFSSVFNAFNYAIETREVMIDRILHEVEVCEAHARKETSAGVN FFKTLGIANLGDNPVFRKVFNDEAMFSRRRDTLTRTIYADLTISDLFDLRLPFQSKSIEDSPSSASSTTITNALTLASVV GTGQLIRSTSLVRDILSFTQFVDIEVLKKLTVPALICGVLAGVAYVVGDIKYAVPRNVSRKLRAEMHEMNYIEQNAGRIA RESRKVLKYPAQDVRSGFQSRIEEQARKKEEFSRTAKEVDSSYKYFKRLHKEVVDQHRLVDRCNLEATLAID
GO term prediction
Biological Process
None predicted.
Molecular Function
GO:0005525 GTP binding
Cellular Component
None predicted.