Protein

MCA_06088_1

Length
497 amino acids


Gene name: MAS2

Description: Alpha subunit of the mitochondrial processing protease (MPP)

Browser: contigD:3212475-3213969+

RNA-seq: read pairs 3517, FPKM 87.3, percentile rank 76.7% (100% = highest expression)

Protein function

Annotation:MAS2Alpha subunit of the mitochondrial processing protease (MPP)
KEGG:K01412PMPCA mitochondrial-processing peptidase subunit alpha [EC:3.4.24.64]
EGGNOG:0PH82MAS2mitochondrial processing peptidase alpha subunit
SGD closest match:S000001066MAS2Mitochondrial-processing peptidase subunit alpha
CGD closest match:CAL0000178676MAS2Mitochondrial-processing protease subunit alpha

Protein alignments

%idAln lengthE-value
MIA_04296_178.37%4670.0MIA_04296_1
A0A0J9X7Q5_GEOCN75.59%4670.0Similar to Saccharomyces cerevisiae YHR024C MAS2 Larger subunit of the mitochondrial processing protease (MPP) OS=Geotrichum candidum GN=BN980_GECA04s05950g PE=3 SV=1
A0A1E3PCS0_9ASCO61.81%4740.0Mitochondrial processing protease 53 kDa subunit OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84376 PE=4 SV=1
A0A167F617_9ASCO60.26%4680.0Mas2p OS=Sugiyamaella lignohabitans GN=MAS2 PE=3 SV=1
A0A060T366_BLAAD61.67%4540.0ARAD1C38346p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C38346g PE=3 SV=1
UniRef50_A0A1S7HA8156.52%4603e-165MAS2 (YHR024C) n=10 Tax=Saccharomycetales TaxID=4892 RepID=A0A1S7HA81_9SACH
MPPA_YEAST56.62%4614e-167Mitochondrial-processing peptidase subunit alpha OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MAS2 PE=1 SV=1
Q6C1U0_YARLI56.96%4672e-165YALI0F13409p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F13409g PE=4 SV=1
A0A1E4TGG1_9ASCO54.55%4625e-159Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_26345 PE=4 SV=1
A0A1D8PN84_CANAL46.98%4643e-131Mitochondrial-processing protease subunit alpha OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MAS2 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9992
Predicted cleavage: 35

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 350 400 450 497

Detailed signature matches

    1. SSF63411 (LuxS/MPP-...)
    1. PF00675 (Peptidase_M16)
    1. PF05193 (Peptidase_...)
    1. PS00143 (INSULINASE)
Unintegrated signatures no IPR
Unintegrated signatures

Protein sequence

>MCA_06088_1
MLASVSRLSRRSIPQLSRSSRSLVRSLTSKATTTDETDSMELVTLDNGIKVAVDPNANHFSAMGLYVHAGSRYETPNLQG
LSHIVDRLAFKSTTHRSALEMQQSLESLGGNYMCASSRETMLYQASCFNSDTEQMFSLLAETVKSPSVTEEEVINELATA
EYEVNEIWQKPELILPEITHMTAYKGTLGNPLLCPKERLSVITPEHVFEYRDKFYHPDKIVAAFVGVETQRAVDMVEKYL
GDMPKRSLEQKQQEIDAQTYTQPAYYTGGEFSRPSIPPIGNLPEFVHLHIAFEGVATADPDIYALATLQMLLGGGGSFSA
GGPGKGMYSRLYTQVLNQFGYIESCIAFNHSYTDSGLFGISSSCIPNFAPYLADVLCRQLVQTFATGQGALTKAEVQRAK
NQLRSSLLMNLESKMVQLEDMGRQVLVQGYKIPVMEMCEKIDRLTVEDIRRVAKRVLTGNTNNPGMGTGKPTIVIEGRRE
LFGDVEQVIKRYGLGNY

GO term prediction

Biological Process

GO:0006508 proteolysis

Molecular Function

GO:0003824 catalytic activity
GO:0004222 metalloendopeptidase activity
GO:0046872 metal ion binding

Cellular Component

None predicted.