Protein

MCA_06058_1

Length
219 amino acids

Gene name: TAD2

Description: tRNA-specific adenosine deaminase subunit TAD2

Browser: contigD:3138177-3139028+

RNA-seq: read pairs 184, FPKM 10.3, percentile rank 26.4% (100% = highest expression)

Protein function

Annotation:TAD2tRNA-specific adenosine deaminase subunit TAD2
KEGG:K15441TAD2 tRNA-specific adenosine deaminase 2 [EC:3.5.4.-]
EGGNOG:0PHDPTAD2adenosine deaminase
SGD closest match:S000003572TAD2tRNA-specific adenosine deaminase subunit TAD2
CGD closest match:CAL0000197395orf19.1458tRNA(Adenine34) deaminase

Protein alignments

%idAln lengthE-value
MIA_00153_167.20%1895e-95MIA_00153_1
A0A1E3PKX8_9ASCO65.56%1808e-88tRNA specific adenosine deaminase (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_7868 PE=4 SV=1
Q6C5Z8_YARLI65.38%1827e-87YALI0E13728p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E13728g PE=4 SV=1
UniRef50_Q6C5Z865.38%1822e-83YALI0E13728p n=62 Tax=Dikarya TaxID=451864 RepID=Q6C5Z8_YARLI
A0A060TEE8_BLAAD60.96%1874e-87ARAD1D06710p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D06710g PE=4 SV=1
A0A1E4TKA5_9ASCO63.53%1703e-78Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_83584 PE=4 SV=1
A0A0J9XFE3_GEOCN67.74%1247e-60Similar to Saccharomyces cerevisiae YJL035C TAD2 Subunit of tRNA-specific adenosine-34 deaminase, forms a heterodimer with Tad3p OS=Geotrichum candidum GN=BN980_GECA11s04014g PE=4 SV=1
TAD2_YEAST45.05%2027e-51tRNA-specific adenosine deaminase subunit TAD2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TAD2 PE=1 SV=1
A0A1D8PGE9_CANAL45.86%1818e-46tRNA(Adenine34) deaminase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1458 PE=4 SV=1
A0A167D456_9ASCO66.07%565e-20Tad2p OS=Sugiyamaella lignohabitans GN=TAD2 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0692

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 20 40 60 80 100 120 140 160 180 200 219

Detailed signature matches

  1. Domain IPR016193
    Cytidine deaminase-like
    1. SSF53927 (Cytidine ...)
  2. Domain IPR002125
    Cytidine and deoxycytidylate deaminase domain
    1. PF00383 (dCMP_cyt_d...)
    2. PS51747 (CYT_DCMP_D...)
  3. SITE IPR016192
    APOBEC/CMP deaminase, zinc-binding
    1. PS00903 (CYT_DCMP_D...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.14...
  2. cd01285 (nucleoside...)
  3. mobidb-lite (disord...)

Residue annotation

  1. nucleoside/Zn bind...
  2. dimer interface cd...
  3. catalytic motif cd...

Protein sequence

>MCA_06058_1
MLERSDQDIEMTTATTIENSNDASNKSIIPDMKSNQHLAEKALNDGEVPVGCILVYNDKIIGNGLNDTNRTMCGVRHAEF
IAIEQALKTYTTSIFPQTDLYVTVEPCIMCASALRQLGIRRVFYGCANDRFGGCGSVLWVNNNPSPVPSYKCYPGFYREE
AIILLRKFYVQENEKAPTPKNKKLRQLKFEVEPLDYKKYVESLEEFVEVYGEDQKHLYC

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0003824 catalytic activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity

Cellular Component

None predicted.