Protein

MCA_06049_1

Length
1,156 amino acids


Gene name: HIR1

Description: Protein HIR1

Browser: contigD:3115783-3119423+

RNA-seq: read pairs 1668, FPKM 17.8, percentile rank 38.2% (100% = highest expression)

Protein function

Annotation:HIR1Protein HIR1
KEGG:K11293HIRA protein HIRA/HIR1
EGGNOG:0PG3QHIR1Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle (By similarity)
SGD closest match:S000000104HIR1Protein HIR1
CGD closest match:CAL0000197832HIR1Protein HIR1

Protein alignments

%idAln lengthE-value
MIA_00148_177.38%3053e-159MIA_00148_1
UniRef50_A0A1G4MAZ249.19%4961e-146Protein HIR n=2 Tax=Lachancea TaxID=300275 RepID=A0A1G4MAZ2_LACFM
A0A0J9XKV2_GEOCN73.38%3082e-148Protein HIR OS=Geotrichum candidum GN=BN980_GECA25s01088g PE=3 SV=1
A0A1E3PI95_9ASCO67.60%3212e-139Protein HIR OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_35209 PE=3 SV=1
A0A060T5P3_BLAAD70.89%2921e-134Protein HIR OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C14102g PE=3 SV=1
HIR1_YARLI64.59%3052e-132Protein HIR1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=HIR1 PE=3 SV=2
A0A1E4TBD3_9ASCO66.33%2944e-125Protein HIR OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_133403 PE=3 SV=1
HIR1_YEAST59.87%2992e-116Protein HIR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HIR1 PE=1 SV=3
A0A167D8K1_9ASCO77.73%2291e-113Protein HIR OS=Sugiyamaella lignohabitans GN=HIR1 PE=3 SV=1
HIR1_CANAL53.31%3174e-105Protein HIR1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=HIR1 PE=3 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1944

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
  3. Domain
  4. Repeat
1 200 400 600 800 1000 1156

Detailed signature matches

    1. SSF50978 (WD40 repe...)
    2. PS50294 (WD_REPEATS...)
    1. SSF50969 (YVTN repe...)
    1. PF07569 (Hira)
    1. PF00400 (WD40)
    2. PS50082 (WD_REPEATS_2)
    3. SM00320 (WD40_4)
    1. PS00678 (WD_REPEATS_1)
    1. PF09453 (HIRA_B)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MCA_06049_1
MRLLKPAWLNHSDEHRLYEIYSIHVSPDGERLATGGLDGKIRIWSTKAVFNSANESTNSFNEKHLLCSMSTHTGAVTVVR
FSPCGRWLASGSDDRVVLIWELDESRAPRAPEFGTPASEANSETWVARKRLIGHDNDVQDLAWSPDSSLLVTVGLDSAII
IWSGTTFEKLKRFDIHQSHVKGVTFDPANKYFATASDDRTVKIIRYHHNHHQQAETSFNIEATISQPFKGSPLSTYYRRC
SWSPDGNHIAAANATNGPVTTVTIINRGTWDSDISLVGHDAPCEIASFCPRMFSMDKDPIYEEELIEEEDDEEEQEHAKE
ETITKSSSGDINTNENKQDGNNNNLTVKKMKKKNKKKKSQPIYPNLITVIATAGQDKTLAIWNTSNPRPLLVARNIASKS
ITDIAWSNSGQALFASSLDGSILVALFEPGELGWVVPLEENKVQLVRYGGGQEASQIPESTGLLQLEKIESKKQKDEKEE
DATKIKKDQDGDAIILEAEAKKSSPLQNPSSSSSGIPQKPDLNTKDRKKILDNVMGNSSGTIQNDSNTTSTPPPSITSDT
PTTTTNTTTPNTNTPTFKKKLSSQKITITKDGKKRVAPMLISSGSIPTSNASSSSAAHRKVSLNAGNIASSPMVVDYTPP
SNALPQGGIPSLLISSKRKQDVLGPNALLDGSSTNDPSSNTGATGTAATGATTTAASTNAANSATNGGISSTNGTNGHHN
KKPRFTEIQYIRPPIFSPAATVAQVRLGVPKVRTYLGRSAPSSSSLPNCILEIRNNPKDSEIVPTKITVTNNGEVLFVDY
LPRYAILAAGDGSKYWAVATEDGSVYIYSINGRRIAPGIVLESCIAFLESNEQWLLAISSVGIVHLWNIDELQGIDSPSS
SSSSSSSSSSGYYSMMLKQGVSLAPILDSSSKHSAEDGLVRAPKITAAMVTDKGNVVVTLSNGDSFTFSQQLCVWVRVSE
SWWAAGSQYWDTTTNAVTSFTSNGSNNTTGLIKTSNSSSPGVISLLEQRANEDTSNTFDMLTGNVRKGTNPRGKYLQHLA
RKRMLKEGYEHFEQYVSTSHLETRMASAQTLQSWDEFCVFTLMYAERLADEGQSGKLDELCGQLFSSSSKDNDKEKEEKH
QLLKKVIAKIGKYRQVSKISGKYAVALGIIPDIDTI

GO term prediction

Biological Process

GO:0006355 regulation of transcription, DNA-templated

Molecular Function

GO:0005515 protein binding

Cellular Component

GO:0005634 nucleus