Protein

MCA_06034_1

Length
328 amino acids

Gene name: NFU1

Description: NifU-like protein, mitochondrial; protein involved in Fe-S cluster transfer to mitochondrial clients

Browser: contigD:3082412-3083399+

RNA-seq: read pairs 4681, FPKM 175.8, percentile rank 86.6% (100% = highest expression)

Protein function

Annotation:NFU1NifU-like protein, mitochondrial; protein involved in Fe-S cluster transfer to mitochondrial clients
EGGNOG:0PJ96FG00654.1HIRA-interacting protein 5
SGD closest match:S000001523NFU1NifU-like protein, mitochondrial
CGD closest match:CAL0000194822CAALFM_CR07670WAUncharacterized protein

Protein alignments

%idAln lengthE-value
MIA_05056_170.82%2576e-119MIA_05056_1
A0A0J9X547_GEOCN67.49%2438e-115Similar to Saccharomyces cerevisiae YKL040C NFU1 Protein involved in iron metabolism in mitochondria OS=Geotrichum candidum GN=BN980_GECA03s00131g PE=4 SV=1
A0A167C680_9ASCO64.94%2519e-112Nfu1p OS=Sugiyamaella lignohabitans GN=NFU1 PE=4 SV=1
UniRef50_A0A167C68064.94%2512e-108Nfu1p n=17 Tax=cellular organisms TaxID=131567 RepID=A0A167C680_9ASCO
A0A1E4TGH5_9ASCO62.30%2444e-104Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_57204 PE=4 SV=1
Q6CG73_YARLI51.75%3156e-100YALI0B00264p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B00264g PE=4 SV=2
A0A060TBY2_BLAAD60.50%2386e-90ARAD1D31570p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D31570g PE=4 SV=1
Q59N44_CANAL54.31%2322e-78Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CAALFM_CR07670WA PE=4 SV=1
A0A1E3PNA0_9ASCO46.67%2705e-69HIRA-interacting protein 5 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45175 PE=4 SV=1
NFU1_YEAST38.43%2683e-47NifU-like protein, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NFU1 PE=1 SV=2

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9949
Predicted cleavage: 66

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 328

Detailed signature matches

  1. Family IPR035433
    NFU1-like
    1. PIRSF036773 (HIRIP5)
  2. Domain IPR014824
    Scaffold protein Nfu/NifU, N-terminal
    1. SSF110836 (Hypothet...)
    2. G3DSA:3.30.13...
    3. SM00932 (Nfu_N_3a)
    4. PF08712 (Nfu_N)
  3. Domain IPR034904
    Fe-S cluster assembly domain
    1. SSF117916 (Fe-S clu...)
    2. G3DSA:3.30.30...
  4. Domain IPR001075
    NIF system FeS cluster assembly, NifU, C-terminal
    1. PF01106 (NifU)
    2. PD002830
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MCA_06034_1
MINSSRIHMLVKSARLVSSTVRPVVMTRRNYIASSYPQNTSTLRRPTSASYTSNTKTIQSLSPRIPVRSMFIQTSPTPND
DALKFLPSQRVLPESYGNKTIEFLSGREAHSSPLARKLFAIDGVKSVMLGPDFLTVEKVPTDHTAAASSGDLSGPSSSSE
GGAGDGSNTPSGGHSWMLLKPEIFAVLTEHLTAGLPVLIPGTEIAHDTQPNEDDDDVVAMIKELIDTRIRPAIQEDGGDI
EYMGFTDDGIVQLKLQGACRSCDSSSVTLKNGIENMLMHYVEEVNGVEQVLDPGEQAALQEFEKFEAKLKNQKGDTAEPE
TSSSPPPL

GO term prediction

Biological Process

GO:0016226 iron-sulfur cluster assembly

Molecular Function

GO:0005506 iron ion binding
GO:0051536 iron-sulfur cluster binding

Cellular Component

None predicted.