Protein

MCA_05970_1

Length
284 amino acids

Gene name: THG1

Description: tRNA(His) guanylyltransferase

Browser: contigD:2898685-2899834-

RNA-seq: read pairs 263, FPKM 11.4, percentile rank 28.2% (100% = highest expression)

Protein function

Annotation:THG1tRNA(His) guanylyltransferase
KEGG:K10761THG1 tRNA(His) guanylyltransferase [EC:2.7.7.79]
EGGNOG:0PGHRTHG1tRNA(His) guanylyltransferase
SGD closest match:S000003256THG1tRNA(His) guanylyltransferase
CGD closest match:CAL0000180708THG1tRNA(His) guanylyltransferase

Protein alignments

%idAln lengthE-value
A0A0J9XDG1_GEOCN68.46%2799e-128tRNA(His) guanylyltransferase OS=Geotrichum candidum GN=BN980_GECA09s01044g PE=3 SV=1
MIA_00438_163.82%2931e-124MIA_00438_1
A0A060TCH2_BLAAD61.99%2714e-122tRNA(His) guanylyltransferase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D42152g PE=3 SV=1
A0A1E3PLC1_9ASCO61.51%2912e-117tRNA(His) guanylyltransferase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_51395 PE=3 SV=1
A0A1E4TKS5_9ASCO58.57%2804e-110tRNA(His) guanylyltransferase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_85001 PE=3 SV=1
Q6C6G1_YARLI51.41%3193e-107tRNA(His) guanylyltransferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E09823g PE=3 SV=1
A0A1D8PQL3_CANAL58.99%2787e-107tRNA(His) guanylyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=THG1 PE=3 SV=1
UniRef50_A7ELG864.19%2298e-103tRNA(His) guanylyltransferase n=2 Tax=Pezizomycotina TaxID=147538 RepID=A7ELG8_SCLS1
THG1_YEAST54.24%2362e-84tRNA(His) guanylyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=THG1 PE=1 SV=1
A0A161HIR7_9ASCO56.43%2415e-82Thg1p OS=Sugiyamaella lignohabitans GN=THG1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.1079

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 284

Detailed signature matches

  1. Family IPR007537
    tRNAHis guanylyltransferase Thg1
    1. PIRSF028980 (tRNAHi...)
  2. Domain IPR024956
    tRNAHis guanylyltransferase catalytic domain
    1. PF04446 (Thg1)
  3. Domain IPR025845
    Thg1 C-terminal domain
    1. PF14413 (Thg1C)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil

Protein sequence

>MCA_05970_1
MANSKYEYVKNFERENYLLPDTWIVVRVDGRGFHRFSDRYKFKKPNDLRALQLMNETAKSLMQSMSDIILAYGDSDEYSF
VLRKNCQLFERRECKLVSTFASTFTALYNHLWGKYFNGGGEEEEEDKEENKLDITMLPTFDARTVVYPNEKTLRDYLSWR
QVDCHINNLYNTTFWTLVLKGGLTGAQAEEKLRGTLSKDKNEILFSEFGINYNNEPEIFKKGTILVRDMSDVNLNEEGKE
LSKRQIEREEKKRRKAEILELHEDFIKDEFWQVKYPWILEKGIK

GO term prediction

Biological Process

GO:0006400 tRNA modification

Molecular Function

GO:0000287 magnesium ion binding
GO:0008193 tRNA guanylyltransferase activity

Cellular Component

None predicted.