Protein

MCA_05968_1

Length
469 amino acids


Browser: contigD:2894994-2896436+

RNA-seq: read pairs 2017, FPKM 53.0, percentile rank 66.6% (100% = highest expression)

Protein function

KEGG:K01867WARS tryptophanyl-tRNA synthetase [EC:6.1.1.2]
EGGNOG:0PII1FG10139.1Tryptophanyl-tRNA synthetase
SGD closest match:S000005457WRS1Tryptophan--tRNA ligase, cytoplasmic
CGD closest match:CAL0000182691WRS1Tryptophan--tRNA ligase

Protein alignments

%idAln lengthE-value
MIA_00436_183.00%4000.0MIA_00436_1
A0A1E3PH69_9ASCO71.32%4010.0Tryptophanyl-tRNA synthetase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52191 PE=3 SV=1
Q6CFA0_YARLI68.92%4150.0YALI0B08943p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B08943g PE=3 SV=1
A0A060T430_BLAAD69.15%4020.0ARAD1C01342p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C01342g PE=3 SV=1
A0A1E4TMB0_9ASCO69.77%3970.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_94510 PE=3 SV=1
Q5A3P4_CANAL66.92%4020.0Tryptophan--tRNA ligase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=WRS1 PE=3 SV=1
A0A0J9X393_GEOCN65.36%4070.0Similar to Saccharomyces cerevisiae YOL097C WRS1 Cytoplasmic tryptophanyl-tRNA synthetase OS=Geotrichum candidum GN=BN980_GECA01s09954g PE=3 SV=1
A0A167DZ31_9ASCO65.22%3910.0Tryptophan--tRNA ligase WRS1 OS=Sugiyamaella lignohabitans GN=WRS1 PE=3 SV=1
UniRef50_C5DEJ464.18%4020.0KLTH0C09768p n=7 Tax=saccharomyceta TaxID=716545 RepID=C5DEJ4_LACTC
SYWC_YEAST64.75%4000.0Tryptophan--tRNA ligase, cytoplasmic OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=WRS1 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0063

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 469

Detailed signature matches

    1. PF00579 (tRNA-synt_1b)
    1. cd00806 (TrpRS_core)
    2. PR01039 (TRNASYNTHTRP)
    1. PS00178 (AA_TRNA_LI...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF52374 (Nucleotid...)
  2. mobidb-lite (disord...)

Residue annotation

  1. active site cd00806
  2. HIGH motif cd00806
  3. dimer interface cd...
  4. KMSKS motif cd00806

Protein sequence

>MCA_05968_1
MSTENENSGTPAPAAKAEQKVTPWEVEGAIVDGQAVGIDYDKLIEQFGTNKINEATLKRFEEATGHKPHRLMRRGIFFSE
RDLNVILDRYEHGQPFFLYTGRGPSSDSMHLGHMIPFLFTKWLQDVFDVPLVVELTDDEKFLFKQNLTIDNVKAFAKENC
KDIIAAGFDVDKTLIFSDLEFVGGAFYENVVKTSRQITISTAKSVFGFQDSDNIGKIHFASIQISTSFSTSFPTIFGKDH
KPIPCLIPCAIDQDPYFRVSRDVAVKLKYPKPSLIHSTFIPALQGVTTKMSASVASSTIYLSDTPNQIKNKINKHAFSGG
RATKEEQEKYGGNPDIDVSFLYLSFFEEDDEKLADIADKYRKGQLLTGDLKKECIKVLQEFIIGFQKARSEITDETLKKF
MSADREFKWGTKPRRVPIKELEKKSEKEGESVAAAAAAGEEGSKKLRWFNVSRKQNPNKEAEKTEEEKA

GO term prediction

Biological Process

GO:0006418 tRNA aminoacylation for protein translation
GO:0006436 tryptophanyl-tRNA aminoacylation

Molecular Function

GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004830 tryptophan-tRNA ligase activity
GO:0005524 ATP binding

Cellular Component

GO:0005737 cytoplasm