Protein

MCA_05958_1

Length
446 amino acids

Gene name: GCN5

Description: Histone acetyltransferase GCN5

Browser: contigD:2866981-2868322-

RNA-seq: read pairs 533, FPKM 14.7, percentile rank 33.7% (100% = highest expression)

Protein function

Annotation:GCN5Histone acetyltransferase GCN5
KEGG:K06062PCAF histone acetyltransferase [EC:2.3.1.48]
EGGNOG:0PFEXGCN5Histone acetyltransferase gcn5
SGD closest match:S000003484GCN5Histone acetyltransferase GCN5
CGD closest match:CAL0000180088GCN5Histone acetyltransferase

Protein alignments

%idAln lengthE-value
MIA_05790_183.46%3810.0MIA_05790_1
A0A0J9X9T4_GEOCN79.14%3740.0Similar to Saccharomyces cerevisiae YGR252W GCN5 Acetyltransferase, modifies N-terminal lysines on histones H2B and H3 OS=Geotrichum candidum GN=BN980_GECA06s02045g PE=4 SV=1
GCN5_YARLI75.94%3740.0Histone acetyltransferase GCN5 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=GCN5 PE=3 SV=1
A0A167DM78_9ASCO75.20%3790.0Histone acetyltransferase GCN5 OS=Sugiyamaella lignohabitans GN=GCN5 PE=4 SV=1
A0A1E3PLZ4_9ASCO68.30%4070.0Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82268 PE=4 SV=1
UniRef50_A0A1E3PLZ468.30%4070.0Uncharacterized protein n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A1E3PLZ4_9ASCO
A0A060T9F4_BLAAD74.47%3760.0ARAD1C37620p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C37620g PE=4 SV=1
GCN5_YEAST70.86%3740.0Histone acetyltransferase GCN5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GCN5 PE=1 SV=1
Q59PZ5_CANAL68.29%3690.0Histone acetyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GCN5 PE=4 SV=1
A0A1E4TEP3_9ASCO63.87%3930.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_64384 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0753

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 446

Detailed signature matches

  1. Domain IPR016181
    Acyl-CoA N-acyltransferase
    1. SSF55729 (Acyl-CoA ...)
  2. Domain IPR000182
    GNAT domain
    1. PF00583 (Acetyltran...)
    2. PS51186 (GNAT)
  3. Domain IPR001487
    Bromodomain
    1. PR00503 (BROMODOMAIN)
    2. SSF47370 (Bromodomain)
    3. SM00297 (bromo_6)
    4. PS50014 (BROMODOMAIN_2)
    5. G3DSA:1.20.92...
    6. PF00439 (Bromodomain)
  4. SITE IPR018359
    Bromodomain, conserved site
    1. PS00633 (BROMODOMAIN_1)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.63...
  2. cd04301 (NAT_SF)
  3. cd05509 (Bromo_gcn5...)
  4. mobidb-lite (disord...)

Residue annotation

  1. Coenzyme A binding...
  2. acetyllysine bindi...

Protein sequence

>MCA_05958_1
MGTVDSPSKRKIDQSTDAESNPINKKQKLENGEDVNKDLIKDEANNNNETTEPEKKEGSDNEEEETPDKPLVTKFIFDGV
EYPYKERPAVLEEMNGIIEFRVVNNDNSKENLMVLTGLKNIFQKQLPKMPREYIARLVFDLSHVSIAVIRKPLTVVGGIT
FRPFETRHFAEIVFCAISSTEQVKGYGAHLMNHLKDYVRNAYNGEVMHFLTYADNYAIGYFKKQGFTKEISLDRSIWMGY
IKDYEGGTIMQCTMLPRIRYLDSNKILLIQKAAIMRKIRGISRSHIVHPGLDFFRKKKGNDDDKVEIKDPLKDIPGLKEA
GWTPEMDELSRRPKRSPHFAVMQVLLSEMQSHGSAWPFKEPVDHDEVADYYEVIKEPMDLSTMEQKLQADLYENFEDFIY
DARLIFNNCRKYNNDSTTYYKHATKLEKFLYSKIRDYPEYSYVLDS

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0005515 protein binding
GO:0008080 N-acetyltransferase activity

Cellular Component

None predicted.