Protein
MCA_05951_2
Length
305 amino acids
Gene name: YDC1
Description: Alkaline ceramidase
Browser: contigD:2850445-2851434+
RNA-seq: read pairs 4719, FPKM 190.5, percentile rank 87.5% (100% = highest expression)
Protein function
| Annotation: | YDC1 | Alkaline ceramidase | |
|---|---|---|---|
| KEGG: | K04711 | ACER3 | dihydroceramidase [EC:3.5.1.-] |
| EGGNOG: | 0PJEF | PGUG_02307 | alkaline |
| SGD closest match: | S000006008 | YDC1 | Alkaline ceramidase YDC1 |
| CGD closest match: | CAL0000177800 | YDC1 | Alkaline dihydroceramidase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_00688_1 | 72.04% | 279 | 4e-134 | MIA_00688_1 |
| A0A060SXS7_BLAAD | 62.94% | 286 | 2e-119 | ARAD1A06996p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A06996g PE=4 SV=1 |
| A0A0J9XH35_GEOCN | 58.30% | 283 | 1e-117 | Similar to Saccharomyces cerevisiae YPL087W YDC1 Alkaline dihydroceramidase OS=Geotrichum candidum GN=BN980_GECA17s00912g PE=4 SV=1 |
| Q5A0Z2_CANAL | 58.02% | 262 | 8e-106 | Alkaline dihydroceramidase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=YDC1 PE=4 SV=1 |
| UniRef50_Q5A0Z2 | 58.02% | 262 | 2e-102 | Alkaline dihydroceramidase n=29 Tax=Saccharomycetales TaxID=4892 RepID=Q5A0Z2_CANAL |
| A0A1E3PH58_9ASCO | 56.55% | 267 | 1e-105 | Alkaline ceramidase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52520 PE=4 SV=1 |
| Q6C8E6_YARLI | 52.76% | 290 | 1e-99 | YALI0D20262p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D20262g PE=4 SV=1 |
| A0A1E4TAQ9_9ASCO | 51.99% | 277 | 4e-87 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_130320 PE=4 SV=1 |
| YDC1_YEAST | 43.96% | 298 | 4e-75 | Alkaline ceramidase YDC1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YDC1 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0733
Protein family membership
- Ceramidase (IPR008901)
Domains and repeats
None predicted.
Detailed signature matches
-
-
PF05875 (Ceramidase)
-
no IPR
Unintegrated signatures
-
CYTOPLASMIC_D... (C...)
-
NON_CYTOPLASM... (N...)
-
-
TRANSMEMBRANE (Tran...)
-
mobidb-lite (disord...)
Protein sequence
>MCA_05951_2 MWFPFSIPYPAIPKEGFWGSPTSTIDWCEENYVVTSYIAEAVNTITNAAFIALAVYALINIIKNKHERHLIFVAIGFITV GVGSWMFHATLLYEYQLLDELPMIYATCIPYWIMFSHGKPRNHSLKVAFQISSAAVTLTAIYLHYRNPTIHQTAYGVLNG IIVLKGVHLAKQHVKDPVASSNLNWLLFFGLTSFLSGYALWNADIHLCDYWRRTRRSWGMPWGFLLEGHGWWHLLTGYGV YFYIVYIEYLGLFLNGSQDKYEFIWDYYGFLPHVDLKQKSQKVSPKIESTPSSSSSSSLKENRKI
GO term prediction
Biological Process
GO:0006672 ceramide metabolic process
Molecular Function
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
Cellular Component
GO:0016021 integral component of membrane