Protein

MCA_05932_1

Length
1,188 amino acids


Gene name: INP53

Description: Polyphosphatidylinositol phosphatase

Browser: contigD:2797331-2800898-

RNA-seq: read pairs 3409, FPKM 35.4, percentile rank 57.4% (100% = highest expression)

Protein function

Annotation:INP53Polyphosphatidylinositol phosphatase
KEGG:K20279SYNJ synaptojanin [EC:3.1.3.36]
EGGNOG:0PGU5INP52SacI domain and endonuclease exonuclease phosphatase family protein
SGD closest match:S000005635INP53Polyphosphatidylinositol phosphatase INP53
CGD closest match:CAL0000196862orf19.7052Phosphatidylinositol-3-/phosphoinositide 5-phosphatase

Protein alignments

%idAln lengthE-value
MIA_00716_166.72%12020.0MIA_00716_1
A0A0J9XDV3_GEOCN56.28%12260.0Similar to Saccharomyces cerevisiae YOR109W INP53 Polyphosphatidylinositol phosphatase (Partial) (Fragment) OS=Geotrichum candidum GN=BN980_GECA11s02650g PE=4 SV=1
A0A1E3PT58_9ASCO60.27%9740.0Uncharacterized protein (Fragment) OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_4149 PE=4 SV=1
UniRef50_A0A1E3PT5860.27%9740.0Uncharacterized protein (Fragment) n=1 Tax=Nadsonia fulvescens var. elongata DSM 6958 TaxID=857566 RepID=A0A1E3PT58_9ASCO
Q6CA28_YARLI56.30%10160.0YALI0D06413p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D06413g PE=4 SV=1
A0A060T6I8_BLAAD57.81%9860.0ARAD1C20460p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C20460g PE=4 SV=1
A0A167FQT5_9ASCO59.61%8220.0Phosphatidylinositol-3-/phosphoinositide 5-phosphatase INP53 OS=Sugiyamaella lignohabitans GN=INP53 PE=4 SV=1
A0A1E4TM38_9ASCO50.05%9330.0Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_17407 PE=4 SV=1
INP53_YEAST47.25%9080.0Polyphosphatidylinositol phosphatase INP53 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=INP53 PE=1 SV=1
A0A1D8PQN8_CANAL44.08%9210.0Phosphatidylinositol-3-/phosphoinositide 5-phosphatase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.7052 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.2746
Predicted cleavage: 20

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 200 400 600 800 1000 1188

Detailed signature matches

    1. PF02383 (Syja_N)
    2. PS50275 (SAC)
    1. SSF56219 (DNase I-like)
    2. PF03372 (Exo_endo_phos)
    1. SM00128 (i5p_5)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MCA_05932_1
MQVYVNRHPRSLALAEGDYVLIIRYAVANIRSGDHHDEKSPPKCIIEFVDRASIDFKQYRLLSPHECQGCLGLIEVKNKD
RDHKDVYLCVITKGAEVARPRPGETVNRIYSVEFYCVNRGDWDFISLDLNGYAIEQNIALAGASDPLPKLHVGAEHPCAN
LRKLLSNGSFYYSTNFDLATTLQYRGVENHSSSLNMDIADRSFMWNSFMIEGLILFRSRLSESQRTALDKCNFLTSAIRG
FAESKDVRIGRFNDPGTLTIISRQSWRRAGTRFNARGVDDEGNVANFVETETILNFGDLVFGFTQIRGSVPVFWEQDASL
MSATINITRSVEATQPAFNKHFDQLVQKFGIVHVVNLLANKSGEIDLSERYKQHILEAKHLKGSLRWTWFDFHAEVAARG
YSQAGRIIPILGDSFYEISFYSDSVKNTSEKTEQMGIFRTNCLDCLDRTNMIQQLISKRALEMFFELHRIAPGVDIWSRH
NIMWADNGDQLSQIYAGTNALKTSYTRSGKMGLAGAIADVTKSVSRMYINNFVDKSRQSTMDALLGRNTDQQQVVLYDPI
NDYVNMELNRRVSDFSSTTEIKIFAGTFNLNGVMSSEDLTKWLFPVDGGDQPPDIVLVGFQEIVELTPSQILNAEPYKRE
FWEKRVLETLNQKDEYVLVRSDQLVGTALMMFVRKAEVNFVRKVEGAMIKTGLGGMAGNKGGVGVSFYFANTSFCFITAH
LAAGTNNVEERHHNYKTISSGLVFSRGRRIMKHDCIIWLGDFNYRVNLPYDVAIDAIKQKRLDILLKEDQLSQQMYRGEA
FPYYDEMEIKFYPTYKFDKDEDVYDTSDKMRTPSWTDRILRKGTNLHQTSYGCVQDIRFSDHRPVYATFKAKVTIVDEEL
KERLAKQLYDSRRAEIGDANDLVSLVDLNETTLTHGLPPPSTDSRKWWLSGGQSSKIDFQVPPGKVINPNRKPNPFIEDR
DFIDKPPLPPRPSTQGSIASIPALAPDNFKPTQIPRTSTFSEGTTSIPAVTPPARATTFTGGSSSTHHRTKSSTPPPVPR
KPTSLRAGKTAKPSESKSALPTLKTDSLPPPPPPRKTNPSPVVGENNKTLPTIRQPTNISVKKNALTSNGSSTSLMDDDA
DAESVRGWTPPPQAQIRSLANSIHSNNSVANLTTGQSTPKSLLDDDGDVGSTGDTGSVPGLTLLQPSK

GO term prediction

Biological Process

GO:0046856 phosphatidylinositol dephosphorylation

Molecular Function

GO:0042578 phosphoric ester hydrolase activity

Cellular Component

None predicted.