Protein

MCA_05923_1

Length
471 amino acids

Gene name: PEX12

Description: Peroxisome assembly protein 12

Browser: contigD:2777750-2779166-

RNA-seq: read pairs 397, FPKM 10.4, percentile rank 26.6% (100% = highest expression)

Protein function

Annotation:PEX12Peroxisome assembly protein 12
KEGG:K13345PEX12 peroxin-12
EGGNOG:0PK77PEX12Peroxisome assembly protein
SGD closest match:S000004628PEX12Peroxisome assembly protein 12
CGD closest match:CAL0000185265PEX12Ubiquitin-protein ligase peroxin 12

Protein alignments

%idAln lengthE-value
MIA_00702_152.67%4864e-169MIA_00702_1
A0A0J9XA27_GEOCN48.41%4714e-153Similar to Saccharomyces cerevisiae YMR026C PEX12 C3HC4-type RING-finger peroxin and E3 ubiquitin ligase,required for peroxisome biogenesis and peroxisomal matrix protein import OS=Geotrichum candidum GN=BN980_GECA06s04080g PE=4 SV=1
UniRef50_A0A0J9XA2748.41%4719e-150Similar to Saccharomyces cerevisiae YMR026C PEX12 C3HC4-type RING-finger peroxin and E3 ubiquitin ligase,required for peroxisome biogenesis and peroxisomal matrix protein import n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XA27_GEOCN
A0A167D1W9_9ASCO45.57%4741e-135Ubiquitin-protein ligase peroxin 12 OS=Sugiyamaella lignohabitans GN=PEX12 PE=4 SV=1
Q6C7N6_YARLI42.41%4742e-124YALI0D26642p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D26642g PE=4 SV=1
A0A060TEM7_BLAAD43.52%4718e-124ARAD1D09020p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D09020g PE=4 SV=1
A0A1E3PI04_9ASCO39.67%4895e-106Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_51638 PE=4 SV=1
A0A1E4TGL7_9ASCO34.07%4557e-82Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_17622 PE=4 SV=1
A0A1D8PGB2_CANAL28.44%5242e-63Ubiquitin-protein ligase peroxin 12 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PEX12 PE=4 SV=1
PEX12_YEAST25.70%4671e-39Peroxisome assembly protein 12 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PEX12 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0277

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 471

Detailed signature matches

  1. Domain IPR006845
    Pex, N-terminal
    1. PF04757 (Pex2_Pex12)
  2. Domain IPR013083
    Zinc finger, RING/FYVE/PHD-type
    1. G3DSA:3.30.40.10
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. NON_CYTOPLASM... (N...)
  3. SSF57850 (RING/U-box)
  4. TRANSMEMBRANE (Tran...)
  5. cd16451 (mRING_PEX12)

Residue annotation

  1. putative Zn bindin...

Protein sequence

>MCA_05923_1
MDYFSSLNASTLDPDTPTLFEIFSSKELDDLIGPCIRYILTFYAQRHPRYLLRVATKFDEIFAVLKLIVEYHHLKNWNST
FTDKFYGLKKTRVLNENLTLLKARQQQVGGSEEAVNLVEKTKRLSKYQIYGSLFIAVVWPYLKEKMDIKYEQLKARSLVR
NMDLEYKRIMEPESVSGESEDQQYQRPKISRKEKFYFLKDYWFYKLYPIVNSGHAAISLMFFLFYMFSKTSAHSLSDWIL
GVKYSRMSNFDYMLADERENQGKILPPLTGNNDEDQDDDTPLIGKVINRLFLDPKRIFSLDNIKKYPLAALSYALPTSMF
LLKFLEWWSSSDFAQKLVSKTGRSAILDGNLPIPKKHQESLETVKEEDKDEQEDEKRIGFGDEKIQEVSKETKTQLKRNS
ILCPLCAEPITNPTAIETGVVFCYTCIYKHLESCDEETGGYCPVTGTRLLQCKYNPELEQWDIGGLRRLVV

GO term prediction

Biological Process

None predicted.

Molecular Function

None predicted.

Cellular Component

None predicted.