Protein
MCA_05919_1
Length
888 amino acids
Browser: contigD:2767124-2769791+
RNA-seq: read pairs 1196, FPKM 16.6, percentile rank 36.5% (100% = highest expression)
Protein function
| KEGG: | K03327 | TC.MATE | multidrug resistance protein, MATE family |
|---|---|---|---|
| EGGNOG: | 0PFXB | FG06173.1 | MATE efflux family protein |
| SGD closest match: | S000001074 | ERC1 | Ethionine resistance-conferring protein 1 |
| CGD closest match: | CAL0000200953 | orf19.6023 | Uncharacterized protein |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_00701_1 | 42.75% | 531 | 1e-115 | MIA_00701_1 |
| UniRef50_A0A0H5C9D5 | 37.04% | 521 | 4e-86 | MTE3 protein n=9 Tax=Saccharomycetales TaxID=4892 RepID=A0A0H5C9D5_CYBJA |
| A0A0J9X518_GEOCN | 63.23% | 223 | 4e-78 | Similar to Saccharomyces cerevisiae YHR032W ERC1 Member of the multi-drug and toxin extrusion (MATE) family of the multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamily OS=Geotrichum candidum GN=BN980_GECA02s07380g PE=4 SV=1 |
| A0A1E3PIB2_9ASCO | 53.39% | 251 | 4e-72 | MATE efflux family protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83146 PE=4 SV=1 |
| A0A167D1V8_9ASCO | 58.30% | 223 | 1e-69 | Erc1p OS=Sugiyamaella lignohabitans GN=ERC1 PE=4 SV=1 |
| A0A060T8Q2_BLAAD | 55.16% | 223 | 4e-66 | ARAD1D09042p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D09042g PE=4 SV=1 |
| A0A1D8PCB5_CANAL | 50.00% | 238 | 4e-62 | Uncharacterized protein OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.6023 PE=4 SV=1 |
| A0A1E4TGI6_9ASCO | 52.91% | 223 | 5e-60 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_44452 PE=4 SV=1 |
| Q6C7N2_YARLI | 51.53% | 229 | 1e-59 | YALI0D26730p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D26730g PE=4 SV=1 |
| ERC1_YEAST | 50.23% | 219 | 5e-57 | Ethionine resistance-conferring protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ERC1 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.2421
Protein family membership
- Multi antimicrobial extrusion protein (IPR002528)
Domains and repeats
None predicted.
Detailed signature matches
no IPR
Unintegrated signatures
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CYTOPLASMIC_D... (C...)
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NON_CYTOPLASM... (N...)
-
-
TRANSMEMBRANE (Tran...)
-
cd13132 (MATE_eukar...)
-
mobidb-lite (disord...)
Residue annotation
-
putative cation bi...
Protein sequence
>MCA_05919_1 MHSHMVFNSARPAIASAPCSPTPFSFLNEQNDQNDHNSSNETESQHPPNLNYPHTSRPPSYSFSSAHIFGCPSPLSSGVD NGSPKTRPSSANRDLHALTQPHKSICMASTNTTTESTSNNISQNATVSSIDPLLDEPTNSAKNFQNTKKFGIFKSDSFNS SPLVRDSHGTTENFSGDHLGNNENNILKSGSVACESHSSTASRSNSISKKISRFGTVYIENNSTLDYEDHESCHFQSSLN GRISKKENTGQATILVASSNSKASSETSALISDYPAEYAKTHQINKVGYSTTCTTNNVGPNGYDDDDHSDSGGENCGEEP SPCQGSSLVGEQLDVTYCYHKNPYISEMIYILKHTGPIIVTFLLQFSLTVASIFSVGHLGETELAAASLAAMTANITGFA VIQGLATCLDTLCAQSFGAKKYHLVGQYLVKCILMIMTYFIFLALFWLYSEPFLELFVAYDDGDNDDNKMLVPLAACYLK TILFGIPGYIMFECGKRFIQAQGIFYASTCVLVIVAPLNAVLNYTLVWSPYIGIGFRGAPIAVAISQWLMAILLYIFIYF VVDNGKRCWPTISFTRLDSTNKQSQFLNSQSPKYENYGSISSTSSSSSSLIERELTEDEYDRDSTLYDENSLSDYRMTNS IYWCEIFKNWNELLKLAVPGVMMTEAEFLAFEVLTISASKLGTAQLAAQSVLATMSTLLYQIPFSLSIATSTRIANLLGA GCVNRAQVVKKSCLFIAIIWGSLDSFLLYYFRHWASRLFSDDETVIKYIVETIPVLVICTTADAPCAVLSGILRGLGRQC VGGYLNLFSYYTIAIPISLVLTFMYDQQLKGLWAGISVGLICIDLGEYFYTECLIDFDQLVREVKARQEEGHSTCNSRET NPDEPLMV
GO term prediction
Biological Process
GO:0006855 drug transmembrane transport
GO:0055085 transmembrane transport
Molecular Function
GO:0015238 drug transmembrane transporter activity
GO:0015297 antiporter activity
Cellular Component
GO:0016020 membrane