Protein

MCA_05911_1

Length
185 amino acids

Description: protein with thioredoxin domain

Browser: contigD:2746156-2746791+

RNA-seq: read pairs 2731, FPKM 181.4, percentile rank 86.9% (100% = highest expression)

Protein function

Annotation:protein with thioredoxin domain
KEGG:K11187PRDX5 peroxiredoxin 5, atypical 2-Cys peroxiredoxin [EC:1.11.1.15]
EGGNOG:0PN2BFG00353.1AhpC TSA family protein
SGD closest match:S000004099AHP1Peroxiredoxin type-2
CGD closest match:CAL0000177771TRP99Trp99p

Protein alignments

%idAln lengthE-value
MIA_04499_168.48%1842e-89MIA_04499_1
A0A1E3PCM2_9ASCO58.29%1873e-74Redoxin OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84604 PE=4 SV=1
A0A161HN08_9ASCO57.67%1891e-73Ahp1p OS=Sugiyamaella lignohabitans GN=AHP1 PE=4 SV=1
A0A060THU2_BLAAD58.33%1682e-70ARAD1D34100p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D34100g PE=4 SV=1
A0A0J9X365_GEOCN60.47%1728e-68Similar to Saccharomyces cerevisiae YLR109W AHP1 Thiol-specific peroxiredoxin OS=Geotrichum candidum GN=BN980_GECA01s01385g PE=4 SV=1
Q6CB90_YARLI62.03%1587e-65YALI0C21043p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C21043g PE=4 SV=1
A0A1E4TGP4_9ASCO57.32%1571e-64Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_25688 PE=4 SV=1
UniRef50_A0A1E4TGP457.32%1574e-61Uncharacterized protein n=4 Tax=saccharomyceta TaxID=716545 RepID=A0A1E4TGP4_9ASCO
A0A1D8PDN3_CANAL57.76%1613e-63Trp99p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=TRP99 PE=4 SV=1
AHP1_YEAST35.86%1452e-19Peroxiredoxin type-2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AHP1 PE=1 SV=4

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9864

Protein family membership

None predicted.

Domains and repeats

  1. Domain
1 20 40 60 80 100 120 140 160 185

Detailed signature matches

  1. Domain IPR012336
    Thioredoxin-like fold
    1. SSF52833 (Thioredox...)
  2. Domain IPR013766
    Thioredoxin domain
    1. PS51352 (THIOREDOXIN_2)
  3. Domain IPR013740
    Redoxin
    1. PF08534 (Redoxin)
Unintegrated signatures no IPR
Unintegrated signatures
  1. G3DSA:3.40.30.10
  2. cd03013 (PRX5_like)

Residue annotation

  1. catalytic triad cd...
  2. dimer interface cd...

Protein sequence

>MCA_05911_1
MYAARRQLLQTATKSSSSRLFHTTPRVLLKAGDAVPSVEIHEGSPGNTVDLSKETAKGKYIIVGVPGAFSPACSSSHAPG
YIKNFDKLAQKGVDGVFVVAVNDAFVTKAWADSLNTTDKVRFLADAKGEFSKAFDTLFDASKFFGNSRTKRYAAIIQDGK
VVKEFVEPDSTGLDVSVAENILKNL

GO term prediction

Biological Process

GO:0045454 cell redox homeostasis

Molecular Function

GO:0016491 oxidoreductase activity

Cellular Component

None predicted.