MCA_05898_1

Protein

Length

585 amino acids

RNA-seq: read pairs 6015, FPKM 126.8, percentile rank 82.6% (100% = highest expression)

Protein function

KEGG:	K00681	ggt	gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
EGGNOG:	0PIB1	PGUG_04562	gamma-glutamyltranspeptidase
CGD closest match:	CAL0000189923	ECM38	Ecm38p

Protein alignments

	%id	Aln length	E-value
MIA_05012_1	61.47%	597	0.0	MIA_05012_1
A0A0J9XCD0_GEOCN	50.77%	581	1e-175	Similar to Saccharomyces cerevisiae YLR299W ECM38 Gamma-glutamyltranspeptidase, major glutathione-degrading enzyme OS=Geotrichum candidum GN=BN980_GECA09s02133g PE=4 SV=1
A0A060T5W5_BLAAD	48.54%	581	2e-166	ARAD1B10934p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B10934g PE=4 SV=1
A0A167CEA5_9ASCO	48.89%	583	4e-165	Uncharacterized protein OS=Sugiyamaella lignohabitans GN=AWJ20_4400 PE=4 SV=1
A0A1E4TMA5_9ASCO	45.23%	577	7e-150	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_94507 PE=4 SV=1
UniRef50_A0A1E4TMA5	45.23%	577	2e-146	Uncharacterized protein n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A1E4TMA5_9ASCO
A0A1E3PHJ8_9ASCO	45.69%	580	1e-141	Gamma-glutamyltranspeptidase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_51489 PE=4 SV=1
Q6CBA5_YARLI	43.57%	583	4e-139	YALI0C20669p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C20669g PE=4 SV=1
A0A1D8PLV5_CANAL	39.63%	588	1e-104	Ecm38p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ECM38 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0279

Protein family membership

Gamma-glutamyltranspeptidase (IPR000101)

Domains and repeats

Domain
2 - 581
Nucleophile aminohydrolases, N-terminal (IPR029055)

1 100 200 300 400 500 585

Detailed signature matches

IPR000101

Gamma-glutamyltranspeptidase
1. PF01019 (G_glu_tran...)
  
  2 - 578
  
  Pfam
  PF01019 (G_glu_transpept)
2. PR01210 (GGTRANSPTASE)
  
  385 - 403
  
  PRINTS
  PR01210 (GGTRANSPTASE)
  
  416 - 431
  
  PRINTS
  PR01210 (GGTRANSPTASE)
  
  1 - 10
  
  PRINTS
  PR01210 (GGTRANSPTASE)
  
  248 - 267
  
  PRINTS
  PR01210 (GGTRANSPTASE)
  
  361 - 379
  
  PRINTS
  PR01210 (GGTRANSPTASE)
IPR029055

Nucleophile aminohydrolases, N-terminal
1. SSF56235 (N-termina...)
  
  2 - 581
  
  SUPERFAMILY
  SSF56235 (N-terminal nucleophile aminohydrolases (Ntn hydrolases))

no IPR

Unintegrated signatures

NON_CYTOPLASM... (N...)

19 - 585

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
SIGNAL_PEPTIDE (Sig...)

1 - 18

PHOBIUS
SIGNAL_PEPTIDE (Signal Peptide)
SIGNAL_PEPTID... (S...)

14 - 18

PHOBIUS
SIGNAL_PEPTIDE_C_REGION (Signal peptide C-region)
SIGNAL_PEPTID... (S...)

2 - 13

PHOBIUS
SIGNAL_PEPTIDE_H_REGION (Signal peptide H-region)
SIGNAL_PEPTID... (S...)

1 - 1

PHOBIUS
SIGNAL_PEPTIDE_N_REGION (Signal peptide N-region)

Protein sequence

>MCA_05898_1
MAVVAAAAVLGLLEPHMTGPGGDMFALFYDKKSRTVRGINGSGRSPKALSYDQVVRDVAEFNKKTNSKSKSSIPGIPSAL
VHSVTVPGAVAGWIDTVETFGNGKLTMAEILEPAIKLAENGTPIPEITAELWEEGAKTGLANEFLVEDKKTSTQRAPKPG
ELFINKDYAESLKRIADKGKDGFYKGETADAIVNTIQGLGGKLSHEDLQAHKSTLLKAGEPVSTHFIPSTFTSSDSKNKG
KQLRVHEIPPNGQGIVALQTLAILRVLQKEKLIDSLDKYNHNSAEYLHILIESLKGAFRDVGTHTVADLTTETNKIINVK
KVLTDDYIAEILKSSNNANIQFDSKKASTNTNITLGSASDTVYMTATDQWGNACSLINSVYGLFGSKIAPKGLGFVLQNR
GANFNLVKGSPNVYEPEKRPYHTIIPAMVTREPENTEYGKDDDFSGDLYCTYGVMGGFMQPQGHVQVLLNMTVFGYNEQE
ALDAPRICLMPGTPSENEKVVGGTPGGPTTTPETVVAIEEGMPEETIKGLEALGHKVKVIKGGDRALFGRGQVIRWNAYT
EDDEGLIYSAGSDCRGDGAAIPQVF

GO term prediction

Biological Process

GO:0006751 glutathione catabolic process

Molecular Function

GO:0036374 glutathione hydrolase activity

Cellular Component

None predicted.

Filter view on

Entry type

Status

Per-residue features