Protein

MCA_05887_1

Length
436 amino acids

Gene name: SPE2

Description: S-adenosylmethionine decarboxylase proenzyme

Browser: contigD:2649022-2650333-

RNA-seq: read pairs 1237, FPKM 35.0, percentile rank 57.0% (100% = highest expression)

Protein function

Annotation:SPE2S-adenosylmethionine decarboxylase proenzyme
KEGG:K01611speD S-adenosylmethionine decarboxylase [EC:4.1.1.50]
EGGNOG:0PHE5SPE2s-adenosylmethionine decarboxylase
SGD closest match:S000005412SPE2S-adenosylmethionine decarboxylase proenzyme
CGD closest match:CAL0000185891SPE2S-adenosylmethionine decarboxylase proenzyme

Protein alignments

%idAln lengthE-value
MIA_04528_162.03%4740.0MIA_04528_1
A0A0J9XK89_GEOCN61.50%4390.0Similar to Saccharomyces cerevisiae YOL052C SPE2 S-adenosylmethionine decarboxylase, required for the biosynthesis of spermidine and spermine OS=Geotrichum candidum GN=BN980_GECA32s02023g PE=4 SV=1
A0A1E3PSI0_9ASCO51.79%4484e-146S-adenosylmethionine decarboxylase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48553 PE=4 SV=1
UniRef50_A0A1E3PSI051.79%4481e-142S-adenosylmethionine decarboxylase n=1 Tax=Nadsonia fulvescens var. elongata DSM 6958 TaxID=857566 RepID=A0A1E3PSI0_9ASCO
A0A167F4Z8_9ASCO50.33%4495e-142Adenosylmethionine decarboxylase SPE2 OS=Sugiyamaella lignohabitans GN=SPE2 PE=4 SV=1
A0A060TBN8_BLAAD49.10%4462e-137ARAD1D28732p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D28732g PE=4 SV=1
Q6C579_YARLI47.94%4362e-131YALI0E20361p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E20361g PE=4 SV=1
A0A1E4TLB4_9ASCO47.28%4231e-120Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_17174 PE=4 SV=1
DCAM_YEAST38.96%4446e-90S-adenosylmethionine decarboxylase proenzyme OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SPE2 PE=1 SV=1
A0A1D8PMZ8_CANAL35.73%4452e-76S-adenosylmethionine decarboxylase proenzyme OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SPE2 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0103

Protein family membership

Domains and repeats

  1. Domain
1 50 100 150 200 250 300 350 400 436

Detailed signature matches

  1. Family IPR001985
    S-adenosylmethionine decarboxylase
    1. PF01536 (SAM_decarbox)
    2. PIRSF001355 (SAM_de...)
    3. TIGR00535
  2. Domain IPR016067
    S-adenosylmethionine decarboxylase, core
    1. SSF56276 (S-adenosy...)
    2. G3DSA:3.60.90.10
  3. SITE IPR018166
    S-adenosylmethionine decarboxylase, conserved site
    1. PS01336 (ADOMETDC)
Unintegrated signatures no IPR
Unintegrated signatures
  1. mobidb-lite (disord...)

Protein sequence

>MCA_05887_1
MILDTPSKNQEYDNYVNHDLSVQLDSTDAFEGPEKLLEIWFAPDPESLPSDAYPNGLRSVSRANWETMLDIVKCKVLSTV
SSRHMDAFLLSESSMFVFPHKLILKTCGTTTTLIGIPSILDIASSVGLTEAPWRVFYSRKSFMFPEMQLHPHRSWEDEVA
FLDNYFGNGSSYMVGNTNADHWHLYTTEPSPKFPHIFSGTPSSEYFMDFQDETLEVLMTDLDPSAAAQFFTHRLPGAEKL
NFAEDVCGMSDVESSSSLEDSNHDDQDTNSSHVMNNNNKSHSNNGIVVHDDPGHELGALVTKHAKIDEIYHGVNQTIDSF
GFTPCGYSCNTLVGNDGGHYFTIHVTPEKGFSYASFESNVPAGKYGITNSQVLERVVNIFKPGKFSLTLFEAHSKNGSGA
YKIRNLFQNLSGYKRTDRIIYEFDGYDLVFMSFAAR

GO term prediction

Biological Process

GO:0006597 spermine biosynthetic process
GO:0008295 spermidine biosynthetic process

Molecular Function

GO:0004014 adenosylmethionine decarboxylase activity

Cellular Component

None predicted.