MCA_05876_1

Protein

Length

589 amino acids

Gene name: TAM41

Description: Phosphatidate cytidylyltransferase, mitochondrial

Browser: contigD:2609911-2611681-

RNA-seq: read pairs 6513, FPKM 136.4, percentile rank 83.7% (100% = highest expression)

Protein function

Annotation:		TAM41	Phosphatidate cytidylyltransferase, mitochondrial
KEGG:	K17807	TAM41	mitochondrial translocator assembly and maintenance protein 41
EGGNOG:	0PGPT	TAM41	Mitochondrial import protein MMP37
SGD closest match:	S000003278	TAM41	Phosphatidate cytidylyltransferase, mitochondrial
CGD closest match:	CAL0000196310	PTH1	Putative phosphatidate cytidylyltransferase

Protein alignments

	%id	Aln length	E-value
MIA_03017_1	61.74%	460	0.0	MIA_03017_1
A0A0J9XK45_GEOCN	67.41%	402	0.0	Similar to Saccharomyces cerevisiae YGR046W TAM41 Mitochondrial protein required for cardiolipin biosynthesis OS=Geotrichum candidum GN=BN980_GECA25s00791g PE=4 SV=1
A0A060TA93_BLAAD	59.18%	392	2e-161	ARAD1D21956p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D21956g PE=4 SV=1
A0A1E3PCS5_9ASCO	58.09%	408	6e-148	Mitochondrial matrix Mmp37 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_84402 PE=4 SV=1
Q6CC57_YARLI	53.56%	407	5e-145	YALI0C12276p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C12276g PE=4 SV=1
UniRef50_Q6CC57	53.56%	407	1e-141	YALI0C12276p n=4 Tax=Saccharomycetales TaxID=4892 RepID=Q6CC57_YARLI
A0A161HGY3_9ASCO	58.69%	305	1e-108	Tam41p OS=Sugiyamaella lignohabitans GN=TAM41 PE=4 SV=1
A0A1E4TJA3_9ASCO	44.29%	368	2e-87	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30137 PE=4 SV=1
TAM41_YEAST	48.40%	250	1e-62	Phosphatidate cytidylyltransferase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TAM41 PE=1 SV=1
A0A1D8PND1_CANAL	35.15%	367	2e-44	Putative phosphatidate cytidylyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=PTH1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.9977
Predicted cleavage: 36

Protein family membership

Phosphatidate cytidylyltransferase, mitochondrial (IPR015222)

Domains and repeats

None predicted.

Detailed signature matches

IPR015222

Phosphatidate cytidylyltransferase, mitochondrial
1. PIRSF028840 (MMP37)
  
  35 - 143
  
  PIRSF
  PIRSF028840 (MMP37)
  
  156 - 589
  
  PIRSF
  PIRSF028840 (MMP37)
2. PF09139 (Mmp37)
  
  237 - 584
  
  Pfam
  PF09139 (Mmp37)

no IPR

Unintegrated signatures

Coil

160 - 180

COILS
Coil (Coil)
NON_CYTOPLASM... (N...)

37 - 589

PHOBIUS
NON_CYTOPLASMIC_DOMAIN (Non cytoplasmic domain)
SIGNAL_PEPTIDE (Sig...)

1 - 36

PHOBIUS
SIGNAL_PEPTIDE (Signal Peptide)
SIGNAL_PEPTID... (S...)

32 - 36

PHOBIUS
SIGNAL_PEPTIDE_C_REGION (Signal peptide C-region)
SIGNAL_PEPTID... (S...)

20 - 31

PHOBIUS
SIGNAL_PEPTIDE_H_REGION (Signal peptide H-region)
SIGNAL_PEPTID... (S...)

1 - 19

PHOBIUS
SIGNAL_PEPTIDE_N_REGION (Signal peptide N-region)
mobidb-lite (disord...)

44 - 156

MobiDB Lite
mobidb-lite (disorder_prediction)

Protein sequence

>MCA_05876_1
MISRISNRSINMRTLMRSSSLARPSGFLLSTSCRYASIDSQSLANDKTSQNVPLASEQSQNLKSSNSSSSTLVSSSNNFN
SESLGKQNQGSDSSSTTTIHVKVKLSNHSSDNSTDASSSGSKKSVEESIDESDIPRVTPVTNKAHFSEPPPAIEDSDISL
ENLKKTVSEEKLRLLNSNANPIIRKSSKSPKITAQEAKSYLDLNAIPYEKISSFSDLPLEFGYNQHMAIDNQLKEKLRSI
LWKFNAPIKYAFAYGSGVFSQGKASDSTKPQVDMIFGVSYTQHWHSLNMRQNPQHYSFLRHFGSGLVSKVQDNMGSGVYF
NPFVEIDGIKIKYGVVNIDTLLTDLTNWNTLYLAGRLHKPVKILRDEPRIRFTNQANLISALRTALLILPEEFSELDLYR
TLAGISYMGDLRTTFKGLENPHKVENIVQNQFLNFRNLYSPLLDILPNVNLNSSAAFPLDSNHDIGVATMKQDMNPVKRG
NMVVRLPNDFRNRVYQRYQSKYQRIESDFSIKNLDILDPSKNKNLRREGTAFDRAIASDPELPQIISNAIRNTVAWPSFT
QSAKGILTAGIGRSIKYAMAKLSKAQQKK

GO term prediction

Biological Process

GO:0032049 cardiolipin biosynthetic process

Molecular Function

GO:0004605 phosphatidate cytidylyltransferase activity

Cellular Component