Protein

MCA_05806_1

Length
308 amino acids

Gene name: GLC7

Description: Type 1 S/T protein phosphatase (PP1) catalytic subunit

Browser: contigD:2388854-2390151+

RNA-seq: read pairs 9662, FPKM 386.4, percentile rank 93.3% (100% = highest expression)

Protein function

Annotation:GLC7Type 1 S/T protein phosphatase (PP1) catalytic subunit
KEGG:K06269PPP1C serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
EGGNOG:0QDCNPP1serine threonine-protein phosphatase
SGD closest match:S000000935GLC7Serine/threonine-protein phosphatase PP1-2
CGD closest match:CAL0000191628GLC7Serine/threonine-protein phosphatase

Protein alignments

%idAln lengthE-value
MIA_00777_196.04%3030.0MIA_00777_1
A0A060SWU9_BLAAD95.32%2990.0Serine/threonine-protein phosphatase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A08338g PE=3 SV=1
UniRef50_A0A1B8G1L994.39%3030.0Serine/threonine-protein phosphatase n=89 Tax=Eukaryota TaxID=2759 RepID=A0A1B8G1L9_9PEZI
Q59N42_CANAL93.67%3000.0Serine/threonine-protein phosphatase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=GLC7 PE=3 SV=1
A0A1E3PJM5_9ASCO93.38%3020.0Serine/threonine-protein phosphatase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_82635 PE=3 SV=1
Q6CHJ9_YARLI91.78%3040.0Serine/threonine-protein phosphatase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_A08077g PE=3 SV=1
A0A0J9XLM2_GEOCN92.74%3030.0Serine/threonine-protein phosphatase OS=Geotrichum candidum GN=BN980_GECA32s01979g PE=3 SV=1
A0A1E4TF88_9ASCO90.70%3010.0Serine/threonine-protein phosphatase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_105484 PE=3 SV=1
PP12_YEAST90.97%2990.0Serine/threonine-protein phosphatase PP1-2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GLC7 PE=1 SV=1
A0A167ERF2_9ASCO81.67%3000.0Serine/threonine-protein phosphatase OS=Sugiyamaella lignohabitans GN=GLC7 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.5540

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 308

Detailed signature matches

  1. Domain IPR029052
    Metallo-dependent phosphatase-like
    1. SSF56300 (Metallo-d...)
    2. G3DSA:3.60.21.10
  2. Domain IPR031675
    Serine-threonine protein phosphatase, N-terminal
    1. PF16891 (STPPase_N)
  3. Domain IPR004843
    Calcineurin-like phosphoesterase domain, ApaH type
    1. PF00149 (Metallophos)
  4. Domain IPR006186
    Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
    1. PS00125 (SER_THR_PH...)
    2. SM00156 (pp2a_7)
    3. PR00114 (STPHPHTASE)
Unintegrated signatures no IPR
Unintegrated signatures
  1. cd07414 (MPP_PP1_PPKL)

Residue annotation

  1. metal binding site...
  2. active site cd07414
  3. natural toxin bind...
  4. MYPT1 binding site...

Protein sequence

>MCA_05806_1
MTENNSADLNSIIDRLLMVRGSRPGKQVDLLEHEIKFLCTKAREIFIQQPILLELEAPIKICGDIHGQYYDLLRLFEYGG
FPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFILRGNHECASINRIYGFYDECKRRYNVKLWKTFTDCFNCLP
IAAIIDEKIFTMHGGLSPDLNSMEQIRRVMRPTDIPDIGLLCDLLWSDPDKDIVGWSENDRGVSFTFGPDVVSRFLHKHD
MDLICRAHQVVEDGYEFFSKRQLVTLFSAPNYCGEFDNAGAMMSVDESLLCSFQILKPAEKKHSSKKF

GO term prediction

Biological Process

None predicted.

Molecular Function

GO:0016787 hydrolase activity

Cellular Component

None predicted.