Protein
MCA_05801_1
Length
784 amino acids
Gene name: CDC5
Description: Cell cycle serine/threonine-protein kinase CDC5/MSD2; in S. cerevisiae regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis
Browser: contigD:2373651-2376153-
RNA-seq: read pairs 1779, FPKM 28.0, percentile rank 50.6% (100% = highest expression)
Protein function
| Annotation: | CDC5 | Cell cycle serine/threonine-protein kinase CDC5/MSD2; in S. cerevisiae regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis | |
|---|---|---|---|
| KEGG: | K06660 | CDC5 | cell cycle serine/threonine-protein kinase CDC5/MSD2 [EC:2.7.11.21] |
| EGGNOG: | 0PGS0 | CDC5 | serine threonine protein kinase |
| SGD closest match: | S000004603 | CDC5 | Cell cycle serine/threonine-protein kinase CDC5/MSD2 |
| CGD closest match: | CAL0000177027 | CDC5 | Serine/threonine-protein kinase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_05165_1 | 45.50% | 811 | 0.0 | MIA_05165_1 |
| A0A0J9XHY0_GEOCN | 42.80% | 722 | 9e-173 | Serine/threonine-protein kinase OS=Geotrichum candidum GN=BN980_GECA17s01770g PE=3 SV=1 |
| UniRef50_A0A0J9XHY0 | 42.80% | 722 | 2e-169 | Serine/threonine-protein kinase n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XHY0_GEOCN |
| A0A1E3PJ95_9ASCO | 40.28% | 705 | 5e-144 | Serine/threonine-protein kinase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_52079 PE=3 SV=1 |
| CDC5_YEAST | 38.04% | 757 | 5e-136 | Cell cycle serine/threonine-protein kinase CDC5/MSD2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CDC5 PE=1 SV=1 |
| Q6C7R4_YARLI | 38.58% | 692 | 1e-132 | Serine/threonine-protein kinase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D26015g PE=3 SV=1 |
| A0A060T527_BLAAD | 54.99% | 371 | 7e-130 | Serine/threonine-protein kinase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B06974g PE=3 SV=1 |
| Q5ABG0_CANAL | 51.20% | 418 | 2e-126 | Serine/threonine-protein kinase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CDC5 PE=3 SV=1 |
| A0A167C5F0_9ASCO | 37.01% | 662 | 5e-122 | Polo kinase CDC5 OS=Sugiyamaella lignohabitans GN=CDC5 PE=4 SV=1 |
| A0A1E4TDT6_9ASCO | 43.08% | 325 | 1e-77 | Serine/threonine-protein kinase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_1662 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.8785
Predicted cleavage: 38
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
100
200
300
400
500
600
700
784
Detailed signature matches
no IPR
Unintegrated signatures
-
-
-
SSF82615 (Polo-box ...)
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cd14099 (STKc_PLK)
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mobidb-lite (disord...)
Residue annotation
-
ATP binding site c...
-
active site cd14099
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polypeptide substr...
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activation loop (A...
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phosphopeptide bin...
Protein sequence
>MCA_05801_1 MTSRQPLQSIPHMELNKVPNAPMALRSQPIYQKPSRLDSNNIANVAPQHNQAAIATPKPVKSKKEKQKISALCKTPPSTI KAQSSRGNRNFKRGYCLGQGGFARCFQVLDDSGDVYAAKTVAKTSVMSEKNRSKLLAEIKIHKGLDHPNIVKFVDCFEDD TNVYILLEICSNNSLMNMLKTRVYFTEPECRFFLTQIIGAISYMHDFSVIHRDLKLGNIFLDEHMNVKIGDFGLAARLND KSERKKTMCGTPNYIAPEVLDGKEQGGHSYEVDIWSIGIILYAMLYSKPPFQSKNVELIYEKIKATSYAFPDTPEHSDGA KDLISSILVYEPERRPSLEQILSHRFFKTDFPKCLDSSVLTEAPTQFYNMSPKEAEINFNNCKIKAKLAVPSSNSHNRIK SLVMGKSSSDPLEPIDEKHSGPGILPTSLSPASTKEKYKMVMMVKKSNSGKLERGKSGSTLGSSNGKSKLYEQKTDQYDI MPVDNENEDAEVKRSEALKEENLARRAHENNAAATAKQSNSITTNFAPYNQVPDPQSIFHTGLSLIKSLINAQEQGREEY IIQQRYNIQPPSLTYVTQWVDYSNRYGIGYMLSNSYSGLLMSDSVTILLNHNSDSGEIVRYSQSEGAIVTQNVKQIHNAP LPSQYVKRFKLAHTLHNYMNENLRSCGNIDSPCVNCRYRFERGSRSQNGQAERAVYLLNCEKRGGSFFSFQFSNGDLQVN FSDHTKFVFQSNGEGVFFIHSDNIHYLNLRNGHVCCESWYAELTNNTNLLMMVQEKMMILKNEF
GO term prediction
Biological Process
GO:0006468 protein phosphorylation
Molecular Function
GO:0004672 protein kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
Cellular Component
None predicted.