Protein

MCA_05783_1

Length
822 amino acids

Browser: contigD:2316656-2319217+

RNA-seq: read pairs 2629, FPKM 39.5, percentile rank 60.0% (100% = highest expression)

Protein function

EGGNOG:0PGKQPGUG_00090RhoGAP and Fes CIP4 domain protein
SGD closest match:S000001847RGD2Rho-GTPase-activating protein RGD2
CGD closest match:CAL0000176620RGD3Rgd3p

Protein alignments

%idAln lengthE-value
MIA_01882_159.40%6970.0MIA_01882_1
A0A0J9XFD4_GEOCN50.36%6910.0Similar to Saccharomyces cerevisiae YFL047W RGD2 GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p OS=Geotrichum candidum GN=BN980_GECA13s01099g PE=4 SV=1
UniRef50_A0A0J9XFD450.36%6910.0Similar to Saccharomyces cerevisiae YFL047W RGD2 GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p n=2 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XFD4_GEOCN
A0A060T6A9_BLAAD49.22%7010.0ARAD1B10450p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B10450g PE=4 SV=1
A0A167CEK8_9ASCO46.77%7440.0Rgd2p OS=Sugiyamaella lignohabitans GN=RGD2 PE=4 SV=1
Q6C6X5_YARLI47.47%7120.0YALI0E05489p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E05489g PE=4 SV=1
A0A1E3PDI3_9ASCO44.44%7560.0Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_80294 PE=4 SV=1
A0A1D8PTI9_CANAL35.63%7102e-134Rgd3p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=RGD3 PE=4 SV=1
RGD2_YEAST32.80%7535e-117Rho-GTPase-activating protein RGD2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RGD2 PE=1 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0428

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 100 200 300 400 500 600 700 822

Detailed signature matches

  1. Domain IPR027267
    Arfaptin homology (AH) domain/BAR domain
    1. SSF103657 (BAR/IMD ...)
  2. Domain IPR031160
    F-BAR domain
    1. PS51741 (F_BAR)
  3. Domain IPR001060
    FCH domain
    1. PF00611 (FCH)
    2. SM00055 (fch_2)
  4. Domain IPR011991
    Winged helix-turn-helix DNA-binding domain
    1. G3DSA:1.10.10.10
    2. SSF46785 ("Winged h...)
  5. Domain IPR000591
    DEP domain
    1. PF00610 (DEP)
    2. SM00049 (DEP_3)
    3. PS50186 (DEP)
  6. Domain IPR008936
    Rho GTPase activation protein
    1. SSF48350 (GTPase ac...)
  7. Domain IPR000198
    Rho GTPase-activating protein domain
    1. SM00324 (RhoGAP_3)
    2. PF00620 (RhoGAP)
    3. PS50238 (RHOGAP)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. G3DSA:1.10.55...
  3. mobidb-lite (disord...)

Protein sequence

>MCA_05783_1
MSFSTSFWTPDYSTGLNALFEKLNQGCNENDEILALANARAEAEYAYGSRLKDIPITLAPRKDGFGKDDGSTLKKSYEGI
VSEMGEEGDHHVQIAENIRKQVIQPFSQWADKHRQRVEYSQNFLKAGVKQYEKDEQEAQRAQYRYFNKCRLYDAKREEEA
QKLLAEGADPQSLERESSLSSVKSSATSLSTNPTVSRASTIESSNTETDKAEPKAAEEDFEDEVELADIAYSKAMLKELL
HKMLSEIPQTSIKVPIIGVYENVSIGSDIVDWLMHNQTSNSVALAEKFGQDLIQNGFLRLVGSVGSKFANSSVFKYQWKR
KAFITAGIEEEKPTQKNDLITTMAEDYLPGALSSYLNSSSNPNETQVQRLEREVQLLDKKAREAVEKCDETRTALEEQII
EHLNFMEQCERDRLKAIKVVLLDFSGAISNKFAGIKSTIDKYLLYQESIVPERDLRFLIELNKTGSFSPKPVVYDNYYNP
SEGWTFGGELELRARGDGKRMPLIVSSILRYLDELYPKLDDDGLRLAVWTVDVPLKETHKLRKELNNGGPISTEIFDKYR
PPVVGSVLKLYLLELPDSLVPHRFYDTIKELYKMNSSSENPKAKIMALISIFKQIKFSSIATMDGICMHLDRLMTIADVS
EEYRVNIGQQFGPLFLRPKVQTSVTMADRHPYLLVRDLIEHRKDIFKELKRQASMGGSRRSSARRSGSTSSLPGFADAAS
QQANVNLQRNSSFMESSESKFHFTPIAKGKGKTESSTTSSSGSERQNSISGADSAIPEVPTSPARNNVSLTDKVPTGIPS
GAEVIEVDDDDDIQEVPPPPSK

GO term prediction

Biological Process

GO:0007165 signal transduction
GO:0035556 intracellular signal transduction

Molecular Function

None predicted.

Cellular Component

None predicted.