Protein
MCA_05774_1
Length
370 amino acids
Gene name: DYS1
Description: Deoxyhypusine synthase
Browser: contigD:2297903-2299016+
RNA-seq: read pairs 1293, FPKM 43.1, percentile rank 62.1% (100% = highest expression)
Protein function
| Annotation: | DYS1 | Deoxyhypusine synthase | |
|---|---|---|---|
| KEGG: | K00809 | DHPS | deoxyhypusine synthase [EC:2.5.1.46] |
| EGGNOG: | 0PHG4 | DYS1 | Deoxyhypusine synthase |
| SGD closest match: | S000001110 | DYS1 | Deoxyhypusine synthase |
| CGD closest match: | CAL0000180114 | orf19.1626 | Deoxyhypusine synthase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_04480_1 | 82.26% | 372 | 0.0 | MIA_04480_1 |
| A0A0J9X4G5_GEOCN | 79.17% | 360 | 0.0 | Similar to Saccharomyces cerevisiae YHR068W DYS1 Deoxyhypusine synthase, catalyzes formation of deoxyhypusine, the first step in hypusine biosynthesis OS=Geotrichum candidum GN=BN980_GECA02s04905g PE=4 SV=1 |
| A0A161HJG4_9ASCO | 74.59% | 362 | 0.0 | Dys1p OS=Sugiyamaella lignohabitans GN=DYS1 PE=4 SV=1 |
| A0A1E3PQC7_9ASCO | 73.89% | 360 | 0.0 | Deoxyhypusine synthase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_73437 PE=4 SV=1 |
| DHYS_YARLI | 72.50% | 360 | 1e-176 | Deoxyhypusine synthase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=DYS1 PE=3 SV=1 |
| A0A060SXE4_BLAAD | 70.70% | 355 | 5e-176 | ARAD1A12562p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A12562g PE=4 SV=1 |
| A0A1E4TDU7_9ASCO | 69.72% | 360 | 1e-172 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_97131 PE=4 SV=1 |
| DHYS_YEAST | 67.83% | 373 | 2e-171 | Deoxyhypusine synthase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DYS1 PE=1 SV=1 |
| UniRef50_P38791 | 67.83% | 373 | 5e-168 | Deoxyhypusine synthase n=75 Tax=Eukaryota TaxID=2759 RepID=DHYS_YEAST |
| A0A1D8PJD2_CANAL | 68.28% | 372 | 4e-169 | Deoxyhypusine synthase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1626 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0301
Protein family membership
- Deoxyhypusine synthase (IPR002773)
Domains and repeats
-
Domain
1
50
100
150
200
250
300
370
Detailed signature matches
-
-
SSF52467 (DHS-like ...)
-
no IPR
Unintegrated signatures
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CYTOPLASMIC_D... (C...)
-
NON_CYTOPLASM... (N...)
-
TRANSMEMBRANE (Tran...)
Protein sequence
>MCA_05774_1 MTDKKEPIVESTGPNLATDAVLKPSVSLDDAVPVSGVDFEKSPNISAFDLVEGMKNMGFQASNLGKACEIINEMRAWRGT HPETGAEQKCTIFLGYTSNLISSGLRSVLKYLVKNKMVSAIVTTAGGVEEDLIKCLAKTYIGEFSLPGADLREKGLNRIG NLLVPNDNYVKFEEWIIPIYDQMLKEQEEAAEQRLAAGSDVNDPTSPGWWTPSEVIHRLGKEIDNEDSVLYWAYKNDIPV FCPALTDGSIGDMLFFHTYKAAPRQLRIDIVADIRKINAMAMAAPKAGMIILGGGIIKHHIANACLMRNGADYAVYINTG QEFDGSDAGARPDEAISWGKIRADAKRVKLYADVTLVFPLIVAATFASGK
GO term prediction
Biological Process
GO:0008612 peptidyl-lysine modification to peptidyl-hypusine
Molecular Function
None predicted.
Cellular Component
None predicted.