Protein

MCA_05767_1

Length
371 amino acids

Gene name: YVH1

Description: Tyrosine-protein phosphatase YVH1

Browser: contigD:2283823-2285047-

RNA-seq: read pairs 1057, FPKM 35.1, percentile rank 57.2% (100% = highest expression)

Protein function

Annotation:YVH1Tyrosine-protein phosphatase YVH1
KEGG:K14819DUSP12 dual specificity phosphatase 12 [EC:3.1.3.16 3.1.3.48]
EGGNOG:0PHFAYVH1Dual specificity phosphatase
SGD closest match:S000001465YVH1Tyrosine-protein phosphatase YVH1
CGD closest match:CAL0000184045YVH1Tyrosine protein phosphatase

Protein alignments

%idAln lengthE-value
MIA_03492_153.94%4065e-126MIA_03492_1
A0A0J9X4M9_GEOCN43.48%3917e-76Similar to Saccharomyces cerevisiae YIR026C YVH1 Protein phosphatase involved in vegetative growth at low temperatures, sporulation, and glycogen accumulation OS=Geotrichum candidum GN=BN980_GECA01s11032g PE=4 SV=1
UniRef50_A0A0J9X4M943.48%3911e-72Similar to Saccharomyces cerevisiae YIR026C YVH1 Protein phosphatase involved in vegetative growth at low temperatures, sporulation, and glycogen accumulation n=1 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9X4M9_GEOCN
A0A1E3PPE9_9ASCO41.64%3778e-67Dual specificity protein phosphatase 12 OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_49620 PE=4 SV=1
A0A1E4TAX0_9ASCO36.64%3631e-61Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32355 PE=4 SV=1
A0A060TGI2_BLAAD35.57%4023e-60ARAD1D30734p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D30734g PE=4 SV=1
PVH1_YEAST31.17%3854e-42Tyrosine-protein phosphatase YVH1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YVH1 PE=1 SV=1
Q6CEZ6_YARLI34.81%2934e-36YALI0B11572p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B11572g PE=4 SV=1
A0A167DYS3_9ASCO34.48%2325e-34Tyrosine protein phosphatase YVH1 OS=Sugiyamaella lignohabitans GN=YVH1 PE=4 SV=1
A0A1D8PSH7_CANAL30.56%3735e-35Tyrosine protein phosphatase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=YVH1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0390

Protein family membership

Domains and repeats

  1. Domain
  2. Domain
1 50 100 150 200 250 300 371

Detailed signature matches

  1. Family IPR016278
    Dual specificity protein phosphatase 12
    1. PIRSF000941 (DUSP12)
  2. Domain IPR029021
    Protein-tyrosine phosphatase-like
    1. SSF52799 ((Phosphot...)
    2. G3DSA:3.90.19...
  3. Domain IPR000340
    Dual specificity phosphatase, catalytic domain
    1. PF00782 (DSPc)
  4. Domain IPR000387
    Tyrosine specific protein phosphatases domain
    1. PS50056 (TYR_PHOSPH...)
  5. Domain IPR020422
    Dual specificity protein phosphatase domain
    1. SM00195 (dsp_5)
    2. PS50054 (TYR_PHOSPH...)
  6. Domain IPR003595
    Protein-tyrosine phosphatase, catalytic
    1. SM00404 (ptp_7)
Unintegrated signatures no IPR
Unintegrated signatures
  1. Coil
  2. mobidb-lite (disord...)

Protein sequence

>MCA_05767_1
MGAMDKVSEDIYVGSIYSLTSVRDLENANITHILSLLRGHVNDMTESGFEHFHIEIDDDDEEDIMRFFDQTNRFIEDAAS
KGSKALVHCIAGISRSVTIATAYILQKKFRDSKMPLEEEKVARALVEETIEEIRTKRSVANPNESFREQLVIYVRSRFNI
SMDSPLYRQWILKKQAEGIPLTGQSPQNIIYLSANGQKEDAQSPSSGMKKLRSNDSSAQVEPSVRPSPLSRPINPNFGRF
QQQTQQQKGPKKSILRCKKCREPLASSTAFIAHEPSNEGYQNGSFNGAPRNGLVNSSIGSQCMQYFMEPAIWMKPELEKG
ELEGKFNCPKCNAKIGSYCWKGGKCSCGTWVTPAIEIQRSRVDEIFMRGSL

GO term prediction

Biological Process

GO:0006470 protein dephosphorylation
GO:0016311 dephosphorylation

Molecular Function

GO:0008138 protein tyrosine/serine/threonine phosphatase activity
GO:0016791 phosphatase activity

Cellular Component

None predicted.