Protein
MCA_05748_1
Length
546 amino acids
Gene name: ZRC1
Description: Vacuolar membrane zinc transporter
Browser: contigD:2236841-2238584-
RNA-seq: read pairs 2943, FPKM 66.5, percentile rank 71.4% (100% = highest expression)
Protein function
| Annotation: | ZRC1 | Vacuolar membrane zinc transporter | |
|---|---|---|---|
| KEGG: | K14688 | SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| EGGNOG: | 0PHDN | FG00947.1 | zinc cadmium resistance protein |
| SGD closest match: | S000004856 | ZRC1 | Zinc/cadmium resistance protein |
| CGD closest match: | CAL0000192596 | orf19.1536 | Zn(2+) transporter |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_03633_1 | 60.75% | 558 | 0.0 | MIA_03633_1 |
| A0A0J9X9X8_GEOCN | 54.56% | 537 | 3e-148 | Similar to Saccharomyces cerevisiae YMR243C ZRC1 Vacuolar membrane zinc transporter, transports zinc from the cytosol into the vacuole for storage OS=Geotrichum candidum GN=BN980_GECA06s02980g PE=4 SV=1 |
| UniRef50_P20107 | 46.49% | 456 | 4e-105 | Zinc/cadmium resistance protein n=43 Tax=Saccharomycetales TaxID=4892 RepID=ZRC1_YEAST |
| ZRC1_YEAST | 46.49% | 456 | 2e-108 | Zinc/cadmium resistance protein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ZRC1 PE=1 SV=2 |
| A0A1E3PQE1_9ASCO | 66.29% | 175 | 1e-70 | Cation efflux protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_45707 PE=4 SV=1 |
| A0A060SXD4_BLAAD | 68.28% | 186 | 8e-68 | ARAD1A12342p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A12342g PE=4 SV=1 |
| A0A167FQJ9_9ASCO | 62.43% | 173 | 1e-64 | Metal cation transporter COT1 OS=Sugiyamaella lignohabitans GN=COT1 PE=4 SV=1 |
| A0A1E4TA36_9ASCO | 54.89% | 184 | 6e-53 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_32092 PE=4 SV=1 |
| Q6C3F5_YARLI | 62.35% | 162 | 1e-52 | YALI0F00176p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F00176g PE=4 SV=1 |
| A0A1D8PGL8_CANAL | 73.64% | 129 | 3e-47 | Zn(2+) transporter OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=orf19.1536 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.0634
Protein family membership
- Cation efflux protein (IPR002524)
Domains and repeats
-
Domain
1
50
100
150
200
250
300
350
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546
Detailed signature matches
no IPR
Unintegrated signatures
-
CYTOPLASMIC_D... (C...)
-
-
NON_CYTOPLASM... (N...)
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SSF160240 (Cation e...)
-
SSF161111 (Cation e...)
-
-
TRANSMEMBRANE (Tran...)
-
mobidb-lite (disord...)
Protein sequence
>MCA_05748_1 MAKLSKEFRILFLIGLDTVFFLLEIIIGYAVNSLALIADAFHMLNDIISLIVAYWAVKVAKSKGVDSKYTYGWQRAEILG ALINAVFLIALCMTIFLEAIQRFIEVPVITNPKLVLVVGSAGLVSNILGLVLFHEHGHSHGGAGHSHGGFMEDEESALLD HDHNGHTHSHGGITESDVLGYNNNTGSSHSINIPDDNSSYTKKMLDDSGPISEVLPSSYVSRISDTPCDYGSTSTTQQTK KHDHSHDHAKENDHDESHSHSHEHSHEHSHENAHSHNHNSHPPRPRALSLTHSNHFHTKPKQVTRSRSANMEGVFLHVLG DALGNVGVIATALIIWKTDYSWKYYMDPTISLIITCIILKTTLPLFRRTSAILLQAVPQTVDANEVKEDIVSLPGVNDVH ELHIWILREDLYVATLHVSVSISPDEFMKLAQRIRTCMNGHGIASTTIQPEFIPKSRANSICGGYYSGSTSGGSNLVPVH ANEISTGGLSAVNSDNIGPLTHNHNCGHSGDAGSSHSSEEEGRITPTCVLQGNLSTGGLQKANNST
GO term prediction
Biological Process
GO:0006812 cation transport
GO:0055085 transmembrane transport
Molecular Function
GO:0008324 cation transmembrane transporter activity
Cellular Component
GO:0016021 integral component of membrane