MCA_05734_1
Gene name: SCS7
Description: Ceramide very long chain fatty acid hydroxylase SCS7
Browser: contigD:2200691-2201861+
RNA-seq: read pairs 13384, FPKM 424.0, percentile rank 93.7% (100% = highest expression)
Protein function
| Annotation: | SCS7 | Ceramide very long chain fatty acid hydroxylase SCS7 | |
|---|---|---|---|
| KEGG: | K19703 | FA2H | 4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase [EC:1.14.18.6] |
| EGGNOG: | 0PH7M | SCS7 | inositolphosphorylceramide-B C-26 hydroxylase |
| SGD closest match: | S000004885 | SCS7 | Ceramide very long chain fatty acid hydroxylase SCS7 |
| CGD closest match: | CAL0000201815 | SCS7 | Ceramide very long chain fatty acid hydroxylase |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_05717_1 | 72.99% | 385 | 0.0 | MIA_05717_1 |
| A0A0J9XCR1_GEOCN | 64.66% | 382 | 2e-161 | Ceramide very long chain fatty acid hydroxylase OS=Geotrichum candidum GN=BN980_GECA09s03310g PE=3 SV=1 |
| A0A1E3PND7_9ASCO | 58.09% | 377 | 1e-142 | Ceramide very long chain fatty acid hydroxylase OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_46190 PE=3 SV=1 |
| A0A167CDG4_9ASCO | 61.02% | 372 | 4e-142 | Ceramide very long chain fatty acid hydroxylase OS=Sugiyamaella lignohabitans GN=SCS7 PE=3 SV=1 |
| UniRef50_A0A167CDG4 | 61.02% | 372 | 1e-138 | Ceramide very long chain fatty acid hydroxylase n=15 Tax=Fungi TaxID=4751 RepID=A0A167CDG4_9ASCO |
| A0A060T7F4_BLAAD | 56.68% | 374 | 1e-134 | Ceramide very long chain fatty acid hydroxylase OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D02816g PE=3 SV=1 |
| Q6C1X0_YARLI | 56.57% | 373 | 2e-131 | Ceramide very long chain fatty acid hydroxylase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F12749g PE=3 SV=1 |
| A0A1E4TG83_9ASCO | 55.67% | 379 | 1e-129 | Ceramide very long chain fatty acid hydroxylase OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_44396 PE=3 SV=1 |
| SCS7_YEAST | 52.32% | 388 | 9e-129 | Ceramide very long chain fatty acid hydroxylase SCS7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SCS7 PE=1 SV=1 |
| Q5A668_CANAL | 51.91% | 393 | 2e-126 | Ceramide very long chain fatty acid hydroxylase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SCS7 PE=3 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.1428
Protein family membership
- Sterol desaturase Scs7 (IPR014430)
Domains and repeats
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Domain
Detailed signature matches
no IPR
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CYTOPLASMIC_D... (C...)
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NON_CYTOPLASM... (N...)
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TRANSMEMBRANE (Tran...)
Protein sequence
>MCA_05734_1 MEFDTTAVPVITKQELAEQVESSDKCLVTLHHRKVYDVTPFLDEHPGGDSLILAYKGMDITEALKDPMSHLHSETCYEML DEMYLVALLATDEEAKKILTDENRTSFQLQGGSSAQGSSTGIDSKTLTGDAEKELHIKTDFNADYVKHKFIDLNKPLLMQ VVFAKYDKEFYLAQIHKPRHYGKGSAPIFGNFMEPLSKTPWWVVPLVWVPVNMYCVSIALRGLPAYVVAPLYVFGLGLWT LIEYLMHRFIFHIEKLLPDHPLAFALHFLLHGVHHYLPMDRMRLVMPPSLFVILCYPIYKLCFFLFPQYYVAMSIFAGGF MGYICYDVTHYSLHHKKLPEFMKEVKKHHLDHHYKNYDLGYGVTSKFWDSVFGTSMSDDVPSRLLKSYK
GO term prediction
Biological Process
GO:0006629 lipid metabolic process
GO:0008610 lipid biosynthetic process
GO:0055114 oxidation-reduction process
Molecular Function
GO:0005506 iron ion binding
GO:0016491 oxidoreductase activity
GO:0020037 heme binding
GO:0080132 fatty acid alpha-hydroxylase activity
Cellular Component
GO:0016021 integral component of membrane