MCA_05710_1

Protein

Length

368 amino acids

Gene name: AHA1

Description: Hsp90 co-chaperone

Browser: contigD:2096271-2097378-

RNA-seq: read pairs 2259, FPKM 75.6, percentile rank 74.2% (100% = highest expression)

Protein function

Annotation:		AHA1	Hsp90 co-chaperone
EGGNOG:	0PHXM	PGUG_02908	Aha1 domain family
SGD closest match:	S000002622	AHA1	Hsp90 co-chaperone AHA1
CGD closest match:	CAL0000188956	AHA1	Aha1p

Protein alignments

	%id	Aln length	E-value
MIA_02749_1	53.08%	373	5e-125	MIA_02749_1
A0A0J9XD35_GEOCN	50.14%	369	8e-108	Similar to Saccharomyces cerevisiae YDR214W AHA1 Co-chaperone that binds to Hsp82p and activates its ATPase activity OS=Geotrichum candidum GN=BN980_GECA10s02144g PE=4 SV=1
UniRef50_A0A0J9XD35	50.14%	369	2e-104	Similar to Saccharomyces cerevisiae YDR214W AHA1 Co-chaperone that binds to Hsp82p and activates its ATPase activity n=3 Tax=Saccharomycetales TaxID=4892 RepID=A0A0J9XD35_GEOCN
A0A060T2X2_BLAAD	41.58%	368	3e-86	ARAD1C32252p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C32252g PE=4 SV=1
Q6CEG4_YARLI	42.93%	375	2e-85	YALI0B15840p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B15840g PE=4 SV=1
A0A1E3PR52_9ASCO	41.40%	372	2e-85	Co-chaperone that binds to Hsp82p and activates its ATPase activity OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_48398 PE=4 SV=1
A0A1D8PU72_CANAL	39.40%	368	5e-81	Aha1p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=AHA1 PE=4 SV=1
AHA1_YEAST	40.59%	372	1e-77	Hsp90 co-chaperone AHA1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AHA1 PE=1 SV=1
A0A1E4TJL3_9ASCO	38.21%	369	7e-76	Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30253 PE=4 SV=1
A0A167DZ14_9ASCO	46.21%	145	6e-36	Aha1p OS=Sugiyamaella lignohabitans GN=AHA1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0337

Protein family membership

Activator of Hsp90 ATPase homologue 1-like (IPR013538)

Domains and repeats

Domain
4 - 160
Activator of Hsp90 ATPase, N-terminal (IPR015310)
226 - 357
START-like domain (IPR023393)

1 50 100 150 200 250 300 368

Detailed signature matches

IPR013538

Activator of Hsp90 ATPase homologue 1-like
1. PF08327 (AHSA1)
  
  236 - 355
  
  Pfam
  PF08327 (AHSA1)
IPR015310

Activator of Hsp90 ATPase, N-terminal
1. PF09229 (Aha1_N)
  
  13 - 158
  
  Pfam
  PF09229 (Aha1_N)
2. SM01000 (Aha1_N_2)
  
  13 - 160
  
  SMART
  SM01000 (Aha1_N_2)
3. SSF103111 (Activato...)
  
  4 - 159
  
  SUPERFAMILY
  SSF103111 (Activator of Hsp90 ATPase, Aha1)
IPR023393

START-like domain
1. G3DSA:3.30.53...
  
  226 - 357
  
  GENE3D
  G3DSA:3.30.530.20 (G3DSA:3.30.530.20)

no IPR

Unintegrated signatures

SSF55961 (Bet v1-like)

229 - 354

SUPERFAMILY
SSF55961 (Bet v1-like)
cd08892 (SRPBCC_Aha1)

230 - 364

CDD
cd08892 (SRPBCC_Aha1)
mobidb-lite (disord...)

190 - 223

MobiDB Lite
mobidb-lite (disorder_prediction)

Residue annotation

putative hydrophob...

231T

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

233M

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

242V

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

243Y

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

244E

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

246F

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

247T

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

252V

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

260P

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

279T

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

281Y

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

283L

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

285G

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

287N

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

289T

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

290G

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

292F

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

295L

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

301I

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

303Q

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

304T

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

317T

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

318L

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

320L

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

322L

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

332K

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

334K

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

336D

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

338I

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

342Q

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

343V

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

344E

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

345D

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

346V

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

347L

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

348D

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

349N

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

350F

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

353Y

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

354Y

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

355T

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)

358I

putative hydrophobic ligand binding site
231T, 233M, 242V, 243Y, 244E, 246F, 247T, 252V, 260P, 279T, 281Y, 283L, 285G, 287N, 289T, 290G, 292F, 295L, 301I, 303Q, 304T, 317T, 318L, 320L, 322L, 332K, 334K, 336D, 338I, 342Q, 343V, 344E, 345D, 346V, 347L, 348D, 349N, 350F, 353Y, 354Y, 355T, 358I
CDD
cd08892 (SRPBCC_Aha1)
putative Hsp90 bin...

292F

putative Hsp90 binding residues
292F, 304T, 317T, 327N, 328E
CDD
cd08892 (SRPBCC_Aha1)

304T

putative Hsp90 binding residues
292F, 304T, 317T, 327N, 328E
CDD
cd08892 (SRPBCC_Aha1)

317T

putative Hsp90 binding residues
292F, 304T, 317T, 327N, 328E
CDD
cd08892 (SRPBCC_Aha1)

327N

putative Hsp90 binding residues
292F, 304T, 317T, 327N, 328E
CDD
cd08892 (SRPBCC_Aha1)

328E

putative Hsp90 binding residues
292F, 304T, 317T, 327N, 328E
CDD
cd08892 (SRPBCC_Aha1)

Protein sequence

>MCA_05710_1
MVVHNPNNWHWVDKNCIDWTRTYFSEKLTEISAQTETPEKKPVTVKITKVKSCEGDVDVCQRKGKVISLFDLKLVVNYEG
EILDNEGDEPKYSRVGGDITVPEIAYDSEEDDYQFEITTLTGQSTKEKDFIKTQVRQLIIPKLRKALAIFGTDLLKEHGS
EIQHPLDQVQSNFTKSNQVESAKLIQNKLNKETSGEAGSTSSSSSTSNTTTTANGSAKSEIPIYNTESATTEMTCRAPAS
EVYETFTDKSRVAAWSRSPPKYTKSLDSSEEVSEPSVGTAYSLFGGNITGEFLSLEKGKLIKQTWRLKEWKAGHYATLTL
ALEQNENETTVKVKFDGIPVGQVEDVLDNFNQYYTKPIMITFGYGSVL

GO term prediction

Biological Process

GO:0006950 response to stress

Molecular Function

GO:0001671 ATPase activator activity
GO:0051087 chaperone binding

Cellular Component

None predicted.

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Entry type

Status

Per-residue features