Protein
MCA_05708_1
Length
322 amino acids
Gene name: COQ3
Description: Ubiquinone biosynthesis O-methyltransferase, mitochondrial
Browser: contigD:2091486-2092455-
RNA-seq: read pairs 1794, FPKM 68.6, percentile rank 72.1% (100% = highest expression)
Protein function
| Annotation: | COQ3 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial | |
|---|---|---|---|
| KEGG: | K00591 | COQ3 | polyprenyldihydroxybenzoate methyltransferase / 3-demethylubiquinol 3-O-methyltransferase [EC:2.1.1.114 2.1.1.64] |
| EGGNOG: | 0PG9Z | COQ3 | hexaprenyldihydroxybenzoate methyltransferase |
| SGD closest match: | S000005456 | COQ3 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial |
| CGD closest match: | CAL0000180484 | COQ3 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_02751_1 | 72.28% | 285 | 1e-138 | MIA_02751_1 |
| A0A0J9XDC2_GEOCN | 59.03% | 288 | 2e-114 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Geotrichum candidum GN=COQ3 PE=3 SV=1 |
| A0A1E3PQL6_9ASCO | 58.06% | 279 | 3e-107 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Nadsonia fulvescens var. elongata DSM 6958 GN=COQ3 PE=3 SV=1 |
| UniRef50_A0A1E3PQL6 | 58.06% | 279 | 8e-104 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial n=2 Tax=Saccharomycetales TaxID=4892 RepID=A0A1E3PQL6_9ASCO |
| A0A060T7Z8_BLAAD | 53.57% | 280 | 2e-97 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Blastobotrys adeninivorans GN=COQ3 PE=3 SV=1 |
| Q6CEG2_YARLI | 54.15% | 277 | 6e-94 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=COQ3 PE=3 SV=1 |
| Q5A4P2_CANAL | 50.71% | 282 | 4e-93 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=COQ3 PE=3 SV=1 |
| A0A167ENB4_9ASCO | 53.98% | 226 | 4e-84 | Hexaprenyldihydroxybenzoate methyltransferase OS=Sugiyamaella lignohabitans GN=COQ3 PE=4 SV=1 |
| COQ3_YEAST | 45.74% | 282 | 2e-73 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=COQ3 PE=1 SV=2 |
| A0A1E4TEG8_9ASCO | 36.43% | 280 | 4e-59 | Uncharacterized protein (Fragment) OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_11345 PE=4 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.9954
Predicted cleavage: 31
Protein family membership
- Ubiquinone biosynthesis O-methyltransferase (IPR010233)
Domains and repeats
-
Domain
1
50
100
150
200
250
322
Detailed signature matches
-
-
SSF53335 (S-adenosy...)
-
no IPR
Unintegrated signatures
Residue annotation
-
S-adenosylmethioni...
Protein sequence
>MCA_05708_1 MISGRVSSRISPSSIRVFKATLLTRQSVRLHSHLSSSSTTGTTSNELSHFAQLADSWWDVNGPQRILHKMNLLRLDFILN LLKSNWNKNSTSKKFIPGYSFDLLPDELRAKYTKQVQEHETELFDSKSPDSPQYKVLDIGCGGGILSECLARLPFTSQVR GIDLSPDVIKVAKAHMAKDPKLAGKLDYRLIELSKLDPKVEKYDIITLFEVLEHVEYPSEVLSQALDRLNPGGWMFLSTM NRTAVSYFTTIFVGEYILKVVPKGTHTLSKYINEEELREWFEQRDDCDVISSEGCIYIPAYGWKLTGPVRMGNYFMAIRK KN
GO term prediction
Biological Process
GO:0006744 ubiquinone biosynthetic process
Molecular Function
GO:0008425 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity
Cellular Component
None predicted.