Protein

MCA_05693_1

Length
1,772 amino acids

Gene name: YBT1

Description: ATP-binding cassette (ABC) transporter; involved in bile acid transport

Browser: contigD:2055130-2060529-

RNA-seq: read pairs 4862, FPKM 33.9, percentile rank 56.1% (100% = highest expression)

Protein function

Annotation:YBT1ATP-binding cassette (ABC) transporter; involved in bile acid transport
EGGNOG:0PHP4PGUG_02215ATP-dependent bile acid permease
SGD closest match:S000003971YBT1ATP-dependent bile acid permease
CGD closest match:CAL0000179549YCF1ATP-binding cassette glutathione S-conjugate transporter

Protein alignments

%idAln lengthE-value
MIA_00322_162.82%18020.0MIA_00322_1
A0A0J9XJ63_GEOCN56.68%16250.0Similar to Saccharomyces cerevisiae YLL048C YBT1 Transporter of the ATP-binding cassette (ABC) family involved in bile acid transport OS=Geotrichum candidum GN=BN980_GECA22s01187g PE=4 SV=1
A0A060SZS5_BLAAD51.46%16460.0ARAD1C02970p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C02970g PE=4 SV=1
A0A1E3PRZ0_9ASCO52.68%16230.0Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_76405 PE=4 SV=1
Q6C5X7_YARLI51.95%15130.0YALI0E14234p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_E14234g PE=4 SV=1
UniRef50_Q6C5X751.95%15130.0YALI0E14234p n=2 Tax=Yarrowia lipolytica TaxID=4952 RepID=Q6C5X7_YARLI
A0A167FTX5_9ASCO52.81%14430.0Bile acid-transporting ATPase YBT1 OS=Sugiyamaella lignohabitans GN=YBT1 PE=4 SV=1
YBT1_YEAST47.06%15320.0ATP-dependent bile acid permease OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YBT1 PE=1 SV=2
A0A1E4TKL2_9ASCO46.52%15240.0Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30494 PE=4 SV=1
A0A1D8PR42_CANAL32.35%14620.0ATP-binding cassette glutathione S-conjugate transporter OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=YCF1 PE=4 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.0536

Protein family membership

None predicted.

Domains and repeats

  1. Domain
  2. Domain
1 200 400 600 800 1000 1200 1400 1600 1772

Detailed signature matches

  1. Domain IPR011527
    ABC transporter type 1, transmembrane domain
    1. PS50929 (ABC_TM1F)
    2. PF00664 (ABC_membrane)
    3. SSF90123 (ABC trans...)
  2. Domain IPR027417
    P-loop containing nucleoside triphosphate hydrolase
    1. SSF52540 (P-loop co...)
  3. Domain IPR003439
    ABC transporter-like
    1. PF00005 (ABC_tran)
    2. PS50893 (ABC_TRANSP...)
  4. Domain IPR003593
    AAA+ ATPase domain
    1. SM00382 (AAA_5)
  5. SITE IPR017871
    ABC transporter, conserved site
    1. PS00211 (ABC_TRANSP...)
Unintegrated signatures no IPR
Unintegrated signatures
  1. CYTOPLASMIC_D... (C...)
  2. G3DSA:1.20.15...
  3. G3DSA:3.40.50...
  4. NON_CYTOPLASM... (N...)
  5. TMhelix
  6. TRANSMEMBRANE (Tran...)
  7. cd03250 (ABCC_MRP_d...)
  8. mobidb-lite (disord...)

Residue annotation

  1. Walker A/P-loop cd...
  2. ATP binding site c...
  3. Q-loop/lid cd03250
  4. ABC transporter si...
  5. Walker B cd03250
  6. D-loop cd03250
  7. H-loop/switch regi...

Protein sequence

>MCA_05693_1
MPGKCASSSWWVYDDFNPCYRHRYTQIIPLSILVISSVLLILYSLVSNKRRNRGLLLREPSLETLEPEQQPLLSTDGENG
SSSYSSTPSTIIVDPTKDILPSEIASYDQDEILVSKVVPFKPLEGLESHHKINQDLESTPLLNDTASITSISSQKLQEEQ
DKEDYAQLSAAGHITIVTVKRSPSEYFKLFVELLGNLLLVGSSVAAFFIPSIYKEWTSTDGTLTALKVIAGFWSYSLLIV
LVRLYLIRISATPTIPLWAHSTTLYLFAFCFYLVTFRSSILHPYSYPSKYFNIFQSLCVLGLFWANFSAKIGDKPGKLYV
KGDIFPSLEPISSIFSLITFSWIDPMIWKGYFHPLTAKDIWELRTDDHSAFAIQAFRSLGSTASLIRRLLKYFLSALVIS
NSWTFIYSLLSFAPPFLLKKILEFVDDPTQTARSVVWLYVVSFLICGIFTNIVQGQSLFIGRRICIRLRSILIGEIYSKT
LRRRATTTKDSKLGKSKEDTDDQVQETDSKDDKEDKEEDEGQANHGAIINLMAVDTFKVSEICAYLHFISQGIFVVLMSA
VFLYILIGWSGFVGIGSTIILMPIQYRISTIYSEYQDKLMTATDKRINKLNEVLQSIRIIKFFAWEEKFADTVMEIREEE
LKHLKIRYILWGLTGLVFYITPVIVTVLTFSCFIFIQKQTLTAPIAFTTLSILNIMSNPLYQLSEMINELLQAKVSLDRI
DDFLSEKETSKYDQLFRANKNRTANSPVIGFEHATFSWESSNALATSKTDFKLRDLDISFKVGELNLIVGPTGSGKTSLL
LALLGEMELVSGNVFIPGGCLRNSVTPDPSTGLAETIAYCSQSAWLLNDTLRNNILFGSEYDPERYKAVINACALSRDLE
ILDAGDKTEIGEKGITLSGGQKQRVSLARAFYSNSKHLILDDCLSAVDSHTALWIYENCLVGPVAKNRTIILVTHNVALT
ISQASFMVIMDNGRVKGQGAPGDMLAQGLLGDDELLTSASITRNASSANLQNNQNPKRVDPETMGEELARKLTAEPPIEI
IEEEEDTKKIKSTKRKGQLIDEESKAEGKVSSEVYLMYMRAMGTKPFWIFLIVLYLCEPGLNIAQSWWIKIWTAAIVDHG
DNNSTSSVYLYNTQVNSITYNAPIYTHVSSFIYNTIGYYYHQAVDSVHTTIHTMDTDSKKSVYYMGIYIFLGVLFAVFSS
FKEIVTFFAGINASRKLFKKLLDNVLQSKIRFFDSTPIGRIMNRFSKDMEGVDQDLSSMASAVFRCVLGALSTTILIAYI
TPMFLVFACFIVVLYWIIGSLYLTMSREVKRIDSISKSPIYQHFGETLSGVSTIRAYGVGDRFIEDNLAKVDNNNRPFFY
LWVANRWLSFRIDFAGSLVSFFAAAMIILSVHRLDAGLAGLSLSYALTFNDYVLWIVRLYAVVEMNMNSVERLQEYMNLD
KEAPAVIPDSRPPSDWPSKGEIKVSNLSLRYAPDLPLVIKNVSFEVPAHSKIGIVGRTGAGKSTIITAFFRFLEADSGSI
IIDGIDISTIGLRDLRQGLAIIPQDPTLFQGTIRSNLDPFNQYSDDEIFEALRRVHLIKAEDLSTIRNNNNNKNKGKGKQ
LPAATTAVETAASTSTATRRHSKRDSIASLEENANLFHDLSTKISEGGSNLSQGQRQLVCLARSLLKAPKVLLLDEATAS
IDYESDAQIQKTIRDEFSQTTILTIAHRLRSIADYDKILVMDAGRAVEYDHPYKLIEDTSTIFHSMCMNSGEFDALVSIS
REAWEKKKNNNS

GO term prediction

Biological Process

GO:0006810 transport
GO:0055085 transmembrane transport

Molecular Function

GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0042626 ATPase activity, coupled to transmembrane movement of substances

Cellular Component

GO:0016021 integral component of membrane