Protein

MCA_05596_1

Length
233 amino acids


Gene name: VMA4

Description: V-type proton ATPase subunit E

Browser: contigD:1763055-1763932+

RNA-seq: read pairs 11356, FPKM 599.6, percentile rank 95.0% (100% = highest expression)

Protein function

Annotation:VMA4V-type proton ATPase subunit E
KEGG:K02150ATPeV1E V-type H+-transporting ATPase subunit E
EGGNOG:0PJA9VMA4Vacuolar ATP synthase subunit e
SGD closest match:S000005859VMA4V-type proton ATPase subunit E

Protein alignments

%idAln lengthE-value
MIA_01897_171.67%2333e-90MIA_01897_1
A0A0J9XAK2_GEOCN64.38%2337e-73Similar to Saccharomyces cerevisiae YOR332W VMA4 Subunit E of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase) OS=Geotrichum candidum GN=BN980_GECA07s00835g PE=3 SV=1
A0A060T3R2_BLAAD61.80%2331e-71ARAD1A11594p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A11594g PE=3 SV=1
A0A1E3PGM7_9ASCO59.83%2296e-70Vacuolar ATP synthase subunit E OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83526 PE=3 SV=1
A0A167EDX8_9ASCO57.51%2334e-68H(+)-transporting V1 sector ATPase subunit E OS=Sugiyamaella lignohabitans GN=VMA4 PE=3 SV=1
A0A1D8PS38_CANAL54.87%2262e-65H(+)-transporting V1 sector ATPase subunit E OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=VMA4 PE=3 SV=1
UniRef50_K0KQH452.33%1933e-57V-type proton ATPase subunit E n=1 Tax=Wickerhamomyces ciferrii (strain F-60-10 / ATCC 14091 / CBS 111 / JCM 3599 / NBRC 0793 / NRRL Y-1031) TaxID=1206466 RepID=K0KQH4_WICCF
Q6C1K0_YARLI55.02%2291e-57YALI0F15631p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_F15631g PE=3 SV=2
VATE_YEAST51.10%2272e-52V-type proton ATPase subunit E OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VMA4 PE=1 SV=4
A0A1E4TJK7_9ASCO45.08%1934e-39Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30219 PE=3 SV=1

Mitochondrial localization by mitoprotII

Probability of mitochondrial location: 0.3154

Protein family membership

Domains and repeats

None predicted.

Detailed signature matches

    1. MF_00311 (ATP_synth...)
    2. PF01991 (vATP-synt_E)
Unintegrated signatures no IPR
Unintegrated signatures
  1. SSF160527 (V-type A...)

Protein sequence

>MCA_05596_1
MPATVAKSLSDDQVAGELRKMVEFIKKEADEKAKEIELKANEEYEIEKASVVRSETAAIDALYERKYKQSKLSQQIAKST
VANKARLKVLEAREDVVTSIFEEASAQLANLTKDTDKYKKVMEGLIEEAALQLLEPSIKVKCKKGDASVVKSVLDDVVKY
YKDATKGKELEAVVDEESFLGDNIAGGVIVSNKSGKIEVNNTFDERLKLLQEQSLPAIRLAVFGPSESRKFFN

GO term prediction

Biological Process

GO:0015991 ATP hydrolysis coupled proton transport

Molecular Function

GO:0046961 proton-transporting ATPase activity, rotational mechanism

Cellular Component

GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain