Protein
MCA_05582_1
Length
979 amino acids
Gene name: FRE2C
Description: Ferric/cupric reductase transmembrane component 2
Browser: contigD:1708631-1711571-
RNA-seq: read pairs 40, FPKM 0.5, percentile rank 6.9% (100% = highest expression)
Protein function
| Annotation: | FRE2C | Ferric/cupric reductase transmembrane component 2 | |
|---|---|---|---|
| EGGNOG: | 0PHSN | FG01789.1 | Ferric-chelate reductase |
| SGD closest match: | S000001703 | FRE2 | Ferric/cupric reductase transmembrane component 2 |
| CGD closest match: | CAL0000193490 | CFL1 | Ferric/cupric reductase transmembrane component 1 |
Protein alignments
| %id | Aln length | E-value | ||
|---|---|---|---|---|
| MIA_05670_1 | 45.00% | 560 | 1e-161 | MIA_05670_1 |
| A0A0J9X3R7_GEOCN | 37.59% | 556 | 8e-121 | Similar to Saccharomyces cerevisiae YKL220C FRE2 Ferric reductase and cupric reductase OS=Geotrichum candidum GN=BN980_GECA01s05268g PE=4 SV=1 |
| UniRef50_A0A0J9XI25 | 34.53% | 614 | 1e-115 | Similar to Saccharomyces cerevisiae YOR384W FRE5 Putative ferric reductase with similarity to Fre2p n=2 Tax=Geotrichum candidum TaxID=1173061 RepID=A0A0J9XI25_GEOCN |
| Q6CF26_YARLI | 36.20% | 558 | 3e-110 | YALI0B10846p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_B10846g PE=4 SV=1 |
| A0A060SVU5_BLAAD | 32.02% | 559 | 1e-92 | ARAD1A00286p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A00286g PE=4 SV=1 |
| A0A167FY66_9ASCO | 33.39% | 554 | 1e-90 | Fre2p OS=Sugiyamaella lignohabitans GN=FRE2 PE=4 SV=1 |
| A0A1E3PIN1_9ASCO | 33.39% | 557 | 8e-89 | Uncharacterized protein OS=Nadsonia fulvescens var. elongata DSM 6958 GN=NADFUDRAFT_83263 PE=4 SV=1 |
| FRE1_CANAL | 32.98% | 573 | 1e-78 | Ferric/cupric reductase transmembrane component 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CFL1 PE=2 SV=2 |
| A0A1E4TLJ4_9ASCO | 28.19% | 603 | 1e-68 | Uncharacterized protein OS=Tortispora caseinolytica NRRL Y-17796 GN=CANCADRAFT_30726 PE=4 SV=1 |
| FRE2_YEAST | 30.95% | 559 | 3e-60 | Ferric/cupric reductase transmembrane component 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FRE2 PE=1 SV=1 |
Mitochondrial localization by mitoprotII
Probability of mitochondrial location: 0.7601
Predicted cleavage: 28
Protein family membership
None predicted.
Domains and repeats
-
Domain
1
100
200
300
400
500
600
700
800
900
979
Detailed signature matches
no IPR
Unintegrated signatures
-
CYTOPLASMIC_D... (C...)
-
-
-
NON_CYTOPLASM... (N...)
-
SFLDG01168 (Ferric_...)
-
SFLDS00052 (Ferric_...)
-
SIGNAL_PEPTIDE (Sig...)
-
SIGNAL_PEPTID... (S...)
-
SIGNAL_PEPTID... (S...)
-
SIGNAL_PEPTID... (S...)
-
SSF52343 (Ferredoxi...)
-
-
-
TRANSMEMBRANE (Tran...)
-
cd06186 (NOX_Duox_l...)
-
mobidb-lite (disord...)
Residue annotation
-
FAD binding pocket...
-
FAD binding motif ...
-
beta-alpha-beta st...
-
NAD pyrophosphate ...
-
NAD binding pocket...
-
NADP ribose bindin...
Protein sequence
>MCA_05582_1 MKSSAFLVLITASGAVAAGNLNGLFRSCVTLLDNLTFECPQNPPPNGIKVPRTRIPQCSCQSVEYIASYADCALRTEHAD PKPALFGLAMMCGLPGLNAGLSVEKIMSIHKNATDYFIDYDSVSIPRGSAPATKDITKKTVLYNPVRVSQEKLKKSFISH SRFYGNMYEGQFYGGIINAYFGFFVVAAMIMNFCKKFFPKQIQFASNISVIKKFRQTIANPATFNRKHGVPAKWMHIINM SVPTRAQTLVLSGYWIMFIIFNLVNYNYFDDSTVSLDSMIAARTGLLACTHLPLLFLFAGRNNILLYLTNWSYDTMSCYH RWLARGMYTMAFVHSVAFTTSYKKVGRYYSFSRSTIVWGIVATVLGAFILFFSLRHFRKHTYEFFLLFHKAFVAFFLIGM FYHVTPVAFSEWIWVTIGIWAFDRAARVIRIIYGGLLTAYFGFIVFAAVVMNFCKRVFPKQVHAVSNIYIVKKFRQYIAN PATCNQKHGVPGKWMKIINMSIPTRAQTIVIIGYWIIYLILNLIKYDVVDSKKFSLVRMIGDRTGIMATAHLPLLFLFAG RNNILLYATNWSYDTMSCYHRWVARGMYLAAFLHSVTFTVSYKSQGKYHSVISEPENIWGVVATVLGALILFTALRHFRE YTYEFFLLCHQIFVVFFLIGAYYHVRPYGYAEWVWATVGIWAFDRAVRLAKIAISGLNSNAECQYYPESDVIKIKINYSE IWGASPGAYAFVYFLKPFWRCWENHPFSLFPSPVPGEEKKLVLCVRAREGWTRYISKFLVKQPNYSMKCPILLEGPYGQH FHLQHNDNILLIAGGIGVTAVYSYVAKLRSQGQSKQITFVWIVRSVEFLSFFRDEIESLVQSDDIKFQIYISQDSTANTP STGSLSDEKRDSSTPSIDNSSSEEKCGEPVFSSRAMSCVSYGRPDLSEFIHNTVSDSAGTTGVMVCGPPSMNDDVRKFVT AEMGVSKNVIDLYVEGFNW
GO term prediction
Biological Process
GO:0055114 oxidation-reduction process
Molecular Function
GO:0016491 oxidoreductase activity
Cellular Component
None predicted.